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		|  | |      Trilogy Associates is a management consulting and business development firm that facilitates business growth and renewal through commercialization of new products.        Here you will find links to many of our email newsletters on wide-ranging topics of business, societal and personal interest.  Most topics relate in some way to our consulting practice focused on medical products and the life sciences.        I hope you find these musings helpful, interesting, even controversial.  And, if you conclude that any of these views was either "right on" or way off the mark, please let me know .       Caution: Links often break over time; it cannot be helped.    Sincerely, Joe Kalinowski Principal   | 
 | Optimize Tech TransferThe effectiveness of technology transfer from academia to industry is ripe for improvement. I tell you how to improve it.Nobody Wants to Use Your ProductProduct designers can make a great contribution to society, to their customers, and to their employers' bottom lines if they would simply do a better job. Here's how.Consider the Innovation TriadLet's agree to reduce the number of disappointing new-product launches. Try my "Innovation Triad."Don't Overspend on Your New-Product StrategyNew-product commercialization activities are always exciting. But don't get carried away. Take a stepwise approach to focus on what is most important.Another Promised "Innovation" Bites the DustMedtech innovation fascinates me. Medtech is, dare I say, cool! So I find it important to examine its failures and successes.The Power of Pre-PrototypeI'm obsessed with the importance of assessing the commercial potential of a new-product idea at the point of conception -- well before serious time and money are consumed by its development.Look before you leap: Examine the LandscapeLandscaping is an important -- often essential -- business tool. Read about landscaping and other interesting stuff.Big Data or Genuine Insight?I'm all for having access to lots of data. Show me the benefits, and let's roll. But ... don't confuse Big Data with genuine insight.How do you know what to build?Advice on the important issue of deciding what new product(s) to build to support your business.Medical Market Research at Home and AbroadThe ways you attack medical market research depend upon your goals and available tools. Here are some guidelines for two important examples.Hearing the Voices of Lead UsersWhether you call them KOLs or lead users, you need to have occasional conversations with those folks.Know a promising new product when you see one?It turns out that we humans are incredibly ill-equipped to make business decisions on a purely rational basis. You can improve your decision-making processes. But it ain't easy.The Future of MedtechMost musings on market trends and predictions tend to focus on specific new products. I think what matters even more are changes in your customers' preferences and behaviors, and the nature of your relationships with those customers.New Medtech: Boondoggle or Breakthrough?Assessing new technologies is tricky business. I try my hand at two recently announced developments, one boondoggle and one potential breakthrough.Collaborative Consulting Works for Both Buyers and SellersIf you don't know about collaborative consulting, you should. Whether you're a buyer or seller of consulting services, this business model can pay handsome dividends.Healthcare and the Apple MystiqueSilicon Valley is coming up short on innovation, especially in healthcare.Is your new-product idea worthy?New ideas are a dime a dozen; the trick is converting one to a cash-producing business.Medtech ConsolidationPerhaps you've read that Medtronic intends to acquire Covidien. This would be a big deal that would ultimately affect most players in the medtech space.Opportunities and DisruptionMust you creatively disrupt a market in order to exploit an opportunity? Maybe so. But maybe not. In either case it makes sense to first examine that opportunity beyond the view of your customer.Doing Technology DealsRoadblocks can be overcome if both seller and buyer remember a few behavioral fundamentals along the way.  Here are my suggestions for navigating this process successfully.Advice for StartupsThe quality of grant proposals from startups that I occasionally review are highly variable, some great and many terrible.  Read a few of my words of wisdom addressed to those grant-writers.Effectively Communicate Your Product Concept, or ElseNo matter where you are in this process, you need a plan, an overarching framework, a Product Concept communication tool.  I may have just what you need.Our 25th Anniversary CelebrationIt's been 25 years since I founded Trilogy Associates in March of 1989. Let me point you to some potentially useful takeaways that might help you on the path to your own "25".Rethink Your Markets and Your Business ModelsDo you have a clear understanding of your market(s) and how you address them? That's what this installment is about. Just some advice that's not exactly rocket science, but reminders of techniques that often work based upon lots of personal experience; plus, an important emerging trend in the medtech space.A Diagnostics MysteryDoes this new IVD supplier represent a radical departure, or is it more of the same wrapped in hype? Do you really know your market?Knowing you must understand your market and actually understanding it are two very different realities.  The latter takes hard work.Thinking Inside the BoxDon't start with a known problem.  Rather, start with solutions that are already familar, then modify them incrementally to innovate!Clinical Insight from Physician PanelsHosting physician panels is a bit like herding smart cats, but it's great for gathering new-product intelligence.Tapping Medical Minds Is At RiskThe newly legislated Sunshine Act is an attempt to expose and moderate physicians' conflicts of interest.  But there's a problem ...Disruption and Medical EthicsAre you undisruptable?  Can a market newcomer attack you from the bottom up?  Market leaders, beware!Healthcare Watchwords: "Cost" and "Design"Aside from clinical value, your medical product must demonstrate cost-effectiveness and user-friendliness.Screen Your New-Product Ideas (or Else)Look before you leap!  See our "Screener to Guide New-Product Assessment".Understand Market Needs: Ask ArtfullyKnowing what and how to ask are critical, rare skills.  Step up to the challenge and really make a difference.10 Guidelines for New-Product DefinitionYou need to somehow discover what folks want, i.e. what will sell.  I give you 10 tips based upon my experience.Forget Brands, Think User TypesEveryone is into branding. It's been the norm in consumer products marketing for decades, and now it's everywhere. Maybe that's wrong. Read why that might be so.Who Do You Call ... to Assess Business Opportunities?Tap the right influential sources to understand your working environment; 7 groups to consider.A POC Ecosystem and Virtual RealityWhat's a point-of-care (POC) ecosystem, and what does it mean for your POC commercialization efforts?Introverts, Partnerships and FDAIntroverts are more likely to be successful business leaders than extroverts.  Who knew?Healthcare Costs and Combination ProductsThere's a new kid on the cost-data block: The Health Care Cost Institute (HCCI)Back to the FutureAre healthcare revolutionaries often outrageous?  Yes.  Are they sometimes ultimately right?  Yes!Let Clinical Needs be Your GuideTry needs-driven innovation -- really.  Consider observational research.A Little Bit of Everything"Supreme" healthcare.  Brainstorming myth.  Pivot for success?  Focus on customer jobs, not products.Our 2011 Consulting EngagementsOur eclectic practice continues.  For proof by example, see a summary of our 2011 activities.Communicating Your VisionConsider our ConceptVision model for selling your concept internally and externally.Killing Your New-Product LaunchSome great lessons can be learned from launch failures and disappointments.China, Nukes and Business DevelopmentOpportunities in China are real, but there are considerable risks to those who do not fully understand its markets, business practices, and government policies.R&D Spending or Innovation Culture?Culture & strategy matter, R&D spending not so much.  Strive to align innovation strategy and corporate culture.Find and Engage Domain Experts for a Better OutcomeSeek out people who know the right people who can help.  Don't just tap your usual sources.Stock Market WisdomThat's an oxymoron. Relax. Focus on the fundamental drivers of success in healthcare.A Radical Proposal for Drug ApprovalsSomething needs to change!  Here's an idea similar to one I suggested several months ago.Medtech Highlights and CautionsMedtech has experienced a healthy decade, thanks partly to M&A.  But beware due diligence shortcomings.How do you innovate?There are two recognized means.  Use both methods, and do them both right.So what's the real problem?Where are the blind spots in your organization that are retarding growth?Physician Insight and R&D InvestmentThree topics, all dealing with innovation in the life sciences and healthcare.Hear the Drumbeats on Cost EffectivenessEvidence mounts that cost effectiveness will separate winners from losers, regardless of which end of the political spectrum "wins".Innovation KillersWant to cripple your ability to innovate? Here are some sure fire ways to do it.The Year Past and Years to ComeA quick look at some highlights in medicine in 2010, then a few perspectives on our society going forward.Innovating Can Become Very ExpensiveStrive to avoid company-killing costs on the path to innovation.The Hard Part is Getting StartedInvolve helpful people early in the process for a better, and often quicker, outcome.Heed the Voice of Your CustomerRead the intriguing story of The Folding Chair and the importance of your VOC efforts.Emerging Changes to FDA's 510(k) PathwayMy critique of FDA's preliminary recommendations of August 2010Price-Setting and Diagnostics PatentsSetting prices based on customer input, and what Bilsky might mean for diagnostics patents.The Seeds and Processes of InnovationTwo key parts of the innovation puzzle, both critically important to companies and societies.Due Diligence and InnovationA new way to look at due diligence, and the innovation scores of life science firms.So you think you have a platform technology?A stepwise plan for sequential licensing and commercialization.Healthcare Blather -- What Else?Healthcare economics, the Medical Device Tax, and 510(k) overhaul.Doing Technology DealsSuggestions for greater success, for sellers and for buyers.Trends Affecting Your Business in 2010Here are some important trends that are likely to affect many, if not all, medtech businesses over the next few years.Your Future in Medical Device MarketsTry some scenario planning to position your business for 2015.Seeing the Forest for the TreesStep back to see the big picture: On your career, on healthcare, and on energy policy.Get Serious about Costs and Tech AssessmentYou must leverage your cost-effectiveness now.  And, put technology assessment to work in your favor.Get Better at Due DiligenceKeep it simple.  Focus on the decisive issues.Try a New PerspectiveThe benefits of taking a step back, plus Google's personal health records.Exploiting the Downturn for AdvantageExercise internal due diligence and get the timing right.A Little Bit of EverythingYour economic story, CER priorities, combo products, and devices shine.Comparative Effectiveness: Why should you care?Addressing the new realities of tomorrow's healthcare environment.Heed the Game-Changers & IVD Economic BenefitsMedtech interest in game-changing opportunities and threats triggers a new Trilogy initiative: Game-Changer Reports.Soon It Will Be All About CostMy prescription for dealing with the reformation of U.S. healthcare.A Business Development RoadmapGet unstuck while taking your first steps in solving a business problem.Quit Lamenting ... Start Growing!Bad news aside, here's a wealth of free business advice you can use.Healthcare Politics & New Tech for the New YearAddressing the U.S. healthcare crisis and checking out some new medtech.Gaining Clinical Insight from DocsPlanning, conducting and interpreting physician interviews.Medical Devices & America: Not to WorryAn industry exec predicts a future absent medical devices as we know them!The Demise of Medical DevicesHow does medtech measure up against biotech?Doing the Right ThingAn argument in favor of collaborating consultants and tapping manifold information sources.Escaping Your Comfort ZoneThere really is danger in your comfort zone!One Account, Multiple CustomersLeverage your existing accounts by reaching out to new users.Uncomfortable Realities and A New OfficeTrilogy relocates to the Research Triangle of North Carolina; worth a look.Spring LandscapingWho needs to understand a business "landscape"?  Why and how?Liability, Doing It Wrong and RecessionsIt's time to hunker down, right?  No!Innovation vs InventionThink they're the same?  Think again.Assessing New TechnologiesWhy do it?  How to do it right.Hearing the Voices of Lead UsersThese early adopters can put you on the path to success.  Here's how to talk with them.PositioningYes, it's Marketing 101.  Try it yourself; I did.Framing Your MessagesIs it just spin or is it vital?  You decide.Validation, Diagnostics and Disruptive TechnologiesWhat's really "disruptive"?  And why does it matter?Dimensions of Opportunity AssessmentQuestions to guide you, and our checklist too.Managing Change and InnovationThink this is essential to business success?  Me too.Innovation and Design ExcellenceSome clever new products in the medtech space.An Embarrassment of RichesAsk for too much and you ask for trouble -- or you don't get nuthin'.(Inaugural) News from Trilogy AssociatesInternal due diligence: key to new-product success.
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