In my experience the vast majority of people with amalgam fillings are observed to manifest a phenomenon called trace mineral derangement in their hair analysis. This condition was first described by Andrew Cutler, PhD in his book "Hair Test Interpretation.  It is characterized by specific  abnormalities of essential minerals which indicate that the person is no longer able to detoxify his body. Such patients frequently have symptoms and signs of glutathione depletion. They have a variety of problems which may include chemical sensitivity, chronic yeast viral or Lyme infections, chronic fatigue, hypothyroidism and brain fog. In my experience, such patients do poorly with synthetic chelators such as DMPS. 

Low glutathione levels appeared to be the key to the problem. Glutathione has several important functions including protecting the body's cells against oxidative stress due to free radicals, enabling the body to detoxify and excrete toxic chemicals and heavy metals, and making it possible for the thyroid gland and immune system to function normally. An important fact that is not well appreciate appreciated is that  DMPS in the absence of glutathione does not cause excretion of heavy metals. Several years ago I had the opportunity to speak with Dr. David Quigg, scientific director of Doctors Data Laboratory. I was fascinated to hear that when he initially began to develop the  DMPS challenge test, he found that patients who were severely toxic with low glutathione levels failed to excrete heavy metals into their urine until glutathione precursors were provided. What does this mean? Well, it shows that such patients did not have the protection of glutathione peroxidases at the time when mercury and other heavy metals were first mobilized.  It is our experience that a high proportion of patients with trace mineral derangement do have adverse side effects in response to synthetic chelators. It is for that reason that I chose to formulate Chelorex® with glutathione precursors so that as their glutathione levels rose, their ability to detoxify improved as well and the incidence of adverse effects was markedly reduced. 

Low glutathione levels in many patients will also render many highly advertised "detoxification agents" ineffectual if they are not absorbed into the body and do not actually raise glutathione levels. Consequently many persons who use synthetic chelators or who use generic remedies like clay, chlorella, citrus pectin and zeolite  and who fail to do adequate testing will experience unsatisfactory results, the main reason being that, you need ingredients that work in synergy with one another supporting the whole chelation process from beginning to end.

Chelorex® is a synergistic blend of ingredients that support glutathione levels, mobilize metals from the cell and protect from mobilized metals being redistributed through out the body something that DMPS only cannot do.