RFA-CA-14-003 Early-Stage Innovative Molecular Analysis Technology Development for Cancer Research (R21) Application due dates: February 20, 2014; May 20, 2014; September 18, 2014 Expires: September 19, 2014
RFA-CA-14-004 Validation and Advanced Development of Emerging Molecular Analysis Technologies for Cancer Research (R33) Application due dates: February 20, 2014; May 20, 2014; September 18, 2014 Expires: September 19, 2014
RFA-CA-14-005 Early-Stage Development of Innovative Technologies for Biospecimen Science (R21) Application due dates: February 20, 2014; May 20, 2014; September 18, 2014 Expires: September 19, 2014
RFA-CA-14-006 Validation and Advanced Development of Emerging Technologies for Biospecimen Science (R33) Application due dates: February 20, 2014; May 20, 2014; September 18, 2014 Expires: September 19, 2014
Cancer Genomics Cloud Pilots (Broad Agency Announcement) Response date: February 27, 2014 RFA-RM-14-001 Computational Analyses Exploiting Reference Epigenomic Maps (R01) Application due date: March 3, 2014 Expires: March 4, 2014
Cancer Research Network (CRN) Pilot Projects Letters of Intent due date: March 3, 2014 Application due date: May 16, 2014
NOT-CA-14-013 Notice of Intent to Publish a Funding Opportunity Announcement for Core Infrastructure and Methodological Research for Cancer Epidemiology Cohorts (UM1)
NOT-CA-14-019 National Cancer Institute (NCI) to Participate in RFA-HL-14-031 "Development of an NIH BD2K Data Discovery Index Coordination Consortium (U24)"
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NOT-OD-13-020 Public Access Compliance Monitor: A New Resource for Institutions to Track Public Access Compliance
NOT-OD-13-042 Changes to Public Access Policy Compliance Efforts Apply to All Awards with Anticipated Start Dates on or after July 1, 2013
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Complex Systems, Health Disparities & Population Health: Building Bridges February 24-25, 2014 in Bethesda, MD
HIV Drug Resistance Program Conference: Host Factors and Cofactors in HIV Infection February 25, 2014 in Frederick, MD (rescheduled from October 16, 2013)
Symposium on Advances in Endometrial Cancer Epidemiology and Biology March 17-18, Harvard University in Boston, MA
Emerging Issues in Head and Neck Cancer Workshop June 2-3, 2014 in San Pietro in Bevagna, Italy
Principles and Practice of Cancer Prevention and Control Course July 7 to August 1, 2014 in Bethesda, MD Applications due: March 15, 2014
Molecular Prevention Course August 4 to August 8, 2014 in Bethesda, MD Applications due: March 15, 2014
International Genetic Epidemiology Society (IGES) Annual Meeting August 28-30, 2014, in Vienna, Austria Abstracts due: June 4, 2014
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EGRP encourages readers to submit items of interest to Cancer Epidemiology Matters E-News. EGRP reserves the right to decide whether or not materials are appropriate for inclusion.
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Epidemiology and Genomics Research Program Division of Cancer Control and Population Sciences National Cancer Institute 9609 Medical Center Drive
4 East, MSC 9763
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2013 in Review
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Key Initiatives, Events, and Publications Sponsored by NCI's Epidemiology and Genomics Research Program
This first Cancer Epidemiology Matters E-News issue of 2014 features key EGRP-funded initiatives, events, and publications from 2013 that supported research into the determinants of cancer occurrence and outcomes in populations. So what exactly did NCI's Epidemiology and Genomics Research Program (EGRP) and its partners do in 2013? EGRP funded valuable research.EGRP made new resources available for cancer epidemiology and genomic research.- The Cancer Genomics and Epidemiology Navigator (CGEN)
CGEN is an integrated, searchable, and regularly updated knowledge base that collates information derived from multiple sources into a centralized search engine. Comprised of grants, publications, and resources that are interlinked, CGEN is intended to facilitate epidemiologic and genomics research. More details about CGEN's features and uses are available in this blog post from October 2013.
- Sample Cancer Epidemiology Grant Applications
In response to requests from investigators, EGRP debuted a new online resource in June 2013 that included examples of successfully funded grant applications for cancer epidemiology research projects. The resource currently has five examples of applications for R01 and R03 grants, and additional examples of applications for other funding mechanisms will be posted in the future.
- The OncoArray
In collaboration with the Division of Cancer Epidemiology and Genetics (DCEG) and several organizations outside the NIH, the EGRP-funded Genetic Associations and Mechanisms in Oncology initiative (GAME-ON) partnered with Illumina to design a new custom-made genotyping array, the OncoArray, which includes approximately 570,000 single nucleotide polymorphism markers (SNPs). Once completed, data from the OncoArray will be available to members of the OncoArray Network--a group of disease-based consortia interested in gaining new insights into the genetic architecture and mechanisms underlying breast, ovarian, prostate, colorectal, and lung cancers. The EGRP OncoArray web page contains additional details about the array and benefits of joining the OncoArray Network. EGRP staff published original research.Members of EGRP's scientific staff published more than 60 articles in 2013, including original research, meta-analyses, workshop summaries, and commentaries. The full list can be found here by using the CGEN search engine. In collaboration with other programs at NCI and the National Institutes of Health (NIH), EGRP brought together experts and practitioners to collaborate on finding solutions to pressing scientific questions. - Consortia
EGRP currently supports more than 60 national and international research consortia that focus on intradisciplinary and translational research on common and rare cancers. Although we cannot summarize all achievements from these consortia in 2013, notable highlights included:
- The Annual Meeting of the NCI Cohort Consortium, where Consortium members gathered to discuss scientific progress and priorities since the previous year, and identify gaps and new opportunities for collaboration. The public meeting featured presentations on new methods and technologies in cancer epidemiology; breakout sessions where participants discussed types of opportunities, challenges, short-term and long-term efforts, and infrastructure to facilitate and accelerate implementation in the Cohort Consortium; and brief updates on the latest scientific findings and future directions from five working groups. A brief synopsis of the meeting is available on the Cancer Epidemiology Matters Blog and a full summary will be available on the meeting website.
- The 10th Annual Meeting of The Breast Cancer and the Environment Research Program (BCERP), where stakeholders discussed the future of research on breast cancer and the environment and reflected on the program's accomplishments over the past decade. To date, BCERP research has resulted in the discovery of novel biomarkers and the creation of public health interventions, such as the dissemination of toolkits and educational materials about environmental exposures and breast cancer risk. More information about the Annual Meeting is available on the BCERP website and in the December issue of this newsletter.
EGRP used expert input on large-scale issues and opportunities in cancer epidemiology to develop a roadmap for the future. In 2013, EGRP drafted eight recommendations focused on accelerating translation of scientific discoveries in cancer epidemiology (and in the broader field of epidemiology in general) into individual and population health benefits. These were based on the collective intellectual discourse from the " Trends in 21st-Century Epidemiology" workshop and preceding discussions with the scientific community. The recommendations--with proposed corresponding actions for consideration by funding agencies, professional societies, and the research community--were published in a special Cancer Epidemiology, Biomarkers, and Prevention series on "Epidemiology in the 21st Century." EGRP continues to use the workshop recommendations as a framework to ground future scientific planning and priority setting in collaboration with other organizations and other groups within NCI. We look forward to continuing to fund cutting-edge epidemiology and genomics research that will have a measurable impact on reducing the burden of cancer in the United States and globally. If you have ideas for additional resources and opportunities we can provide, email us at [email protected].
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Announcing New Features for NCI-Sponsored Catalogue of Genetic Simulation Software
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The Genetic Simulation Resource (GSR), a catalogue of genetic simulation software for statistical and epidemiological studies of human diseases, was launched in 2013 to help investigators identify the genetic simulator most suitable for their research needs. The GSR website includes detailed descriptions of more than 80 software applications. Users are able to search and compare simulation software on the GSR website so that they can quickly identify the most appropriate software application for their study.
The GSR website was recently updated with new features, which will allow users and developers of genetic simulation programs to:
- Provide comments regarding suitable applications for listed software packages
- Add literature citations to any listed package
- Add new software packages, or modify information from packages already listed in the catalogue
The GSR team encourages all authors of genetic data simulators to list their packages in GSR and publish the official GSR badge--with a link to the GSR site--on their website.
If you have comments or questions about this online resource, contact the GSR team at [email protected].
The GSR is supported by EGRP and the Surveillance Research Program (SRP) in NCI's Division of Cancer Control and Population Sciences (DCCPS).
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