National Cancer Institute
Epidemiology and Genomics Research
October /
November 2013

About Us 

Funding Opportunity

Avon Foundation/NCI/The Center for Advancing Innovation Breast Cancer Start-Up Challenge  

Application due date:  November 29, 2013



NIH Health Care Systems Collaboratory - Demonstration Projects for Pragmatic Clinical Trials Focusing on Multiple Chronic Conditions (UH2/UH3)

Application due date:  December 2, 2013

Expires:  December 3, 2013



Cancer Detection, Diagnosis, and Treatment Technologies for Global Health (UH2/UH3)

Application due date: January 6, 2014

Expires: January 7, 2014


NCI Provocative Questions RFAs 

Application due dates: January 15 and June 20, 2014

Expires:  June 21, 2014



Sub-Saharan African Collaborative HIV and Cancer Consortia (U54)

Application due date:  January 17, 2014

Expires: January 18, 2014 



Interpreting Variation in Human Non-Coding Genomic Regions Using Computational Approaches and Experimental Assessment (R01)

Application due dates:  January 21, 2014; January 21, 2015

Expires January 22, 2015 



Analysis of Genome-Wide Gene-Environment (GxE) Interactions (R21)

Application due date:  February 14, 2014

Expires: February 15, 2014



Nutrigenetics and Nutrigenomics Approaches for Nutrition Research (R01)

Application due dates:  March 20, 2014; March 19, 2015; March 22, 2016

Expires:  March 23, 2016



Research on Malignancies in the Context of HIV/AIDS (R01, R21)

Application due dates:  Standard AIDS dates apply 

Expires: September 8, 2016

Grants Policy InformationGrantsmanshipAnnouncements
Resuming NIH Extramural Activities After the 2013 Government Shutdown

NIH Operates Under a Continuing Resolution


EGRP Job OpportunitiesJobOpportunity

Program Director, Clinical and Translational Epidemiology Branch

Program Director, Host Susceptibility Factors Branch
Upcoming Seminars & WorkshopsEvents
Translational Research in Clinical Oncology - Epigenetics Webinar
November 4, 2013 from 5:00 - 6:00 P.M. EST

Overview of Draft NIH Genomic Data Sharing Policy Webinar
November 6, 2013 from 11 A.M. - 12:30 P.M. EST

3rd Annual Society for Epidemiology Research Digital Student Novel Methods Web Conference
November 6, 2013 from 12:00 - 2:30 P.M. EST

Breast Cancer and the Environment Research Program Extended Environmental Exposures Annual Meeting 

November 6-8, 2013 in Madison, WI


Asia Cohort Consortium Fall Meeting 

November 11-12, 2013 in Tokyo, Japan

2013 Cohort Consortium Annual Meeting 

November 18-19, 2013 in Rockville, MD

Blog Posts


A New Resource for Researching the Epidemiology and Genomics of Cancer: CGEN


Building Team Science - Opportunities to Propose Ancillary Studies to the Framingham Heart Study 

The Epidemiology and Genomics Research Program (EGRP), in the Division of Cancer Control and Population Sciences (DCCPS) funds research in human populations to understand the causes of cancer and related outcomes.

The Program fosters interdisciplinary collaborations, as well as the development and use of resources and technologies to advance cancer research and translation of this research, which serve as the basis for clinical and public health interventions.
Send Us Your IdeasSendUsYourIdeas
EGRP encourages readers to submit items of interest to Cancer Epidemiology Matters E-News. EGRP reserves the right to decide whether or not materials are appropriate for inclusion.
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Epidemiology and Genomics Research Program
Division of Cancer Control and Population Sciences
National Cancer Institute
9609 Medical Center Drive
4 East, MSC 9763
Bethesda, MD  20892
(240) 276-6730

For UPS, FedEx, and courier services, please use:
Rockville, MD  20850
EGRP Launches Searchable Online Database for Cancer Epidemiology and Genomics Researchers CGEN
The Epidemiology and Genomics Research Program (EGRP) is excited to announce the launch of a new online resource for the research community, the Cancer Genomics and Epidemiology Navigator (CGEN).

Created in response to feedback from cancer epidemiologists, CGEN is an integrated, searchable, and regularly updated knowledge base intended to facilitate epidemiologic research.  It collates information derived from multiple sources into a centralized search engine.  Filtering options (by cancer site, risk factors, authorship, etc.) permit users to fine-tune searches.

CGEN includes linked data on:
 More details about potential uses for CGEN can be found in our recent blog post, where we invite you to post your feedback about CGEN, including any suggestions for additional informational resources.  In the coming months, a video tutorial of how to use CGEN will be available on the website.

Or, head to the website now to discover how CGEN can benefit your research. 


What Do You Think of NIH's Draft Genomic Data Sharing Policy?GDSPolicy
Comments Invited by November 20

On September 27, 2013, the National Institutes of Health (NIH) released a Notice in the NIH Guide for Grants and Contracts announcing that it is seeking public comments on a new draft Genomic Data Sharing (GDS) Policy.  The new policy promotes sharing, for research purposes, of large-scale human and nonhuman genomic data generated from NIH-supported and NIH-conducted research. View the NIH Guide Notice.

The draft GDS Policy applies to research involving nonhuman genomic data as well as human data that are generated through array-based and high-throughput genomic technologies (e.g., SNP, whole-genome, transcriptomic, epigenomic, and gene expression data). The NIH considers broader access to such data particularly important because of the opportunities to accelerate research through the power of combining such large and information-rich datasets and making them available for re-analysis by other scientists. The draft GDS Policy is aligned with Administration priorities and a recent directive to agencies to increase public access to digital data resulting from federally-funded research.


To ensure that your comments will be considered, please submit your response to this Request for Information by 11:59 p.m. EST on November 20, 2013. Comments may be submitted using any of the following methods:  

  • Online
  • Mail, hand delivery, or courier (for paper, disk, or CD-ROM submissions) to:

Genomic Data Sharing Policy Team

Office of Science Policy

National Institutes of Health

6705 Rockledge Drive, Suite 750

Bethesda, MD 20892.


NIH will host a webinar on the draft Policy on November 6, 2013 from 11 A.M. to 12:30 P.M. EST. The webinar will provide an overview of the draft GDS Policy and answer questions from the community. Visit the NIH GDS website to learn more about the GDS Policy, see announcements about upcoming webinars on the policy when they are posted, view FAQs, and subscribe to the NIH GDS LISTSERV.


Learn more about genomic datasets available for cancer research and the current data access request process.


NCI Workshop Investigates Use of Existing Biospecimen Resources for Early Cancer Detection  Biospecimens

In an effort to improve early cancer detection by leveraging existing biospecimen resources, cancer researchers from a variety of cohort studies, HMOs, and clinical trials met on the NIH campus in Bethesda, MD, on August 28-29, 2013, to discuss re-purposing clinical and epidemiology cohort resources. The workshop, "Utilizing Existing Clinical and Population Biospecimen Resources for Discovery or Validation of Markers for Early Cancer Detection," was co-sponsored by NCI's EGRP and the Division of Cancer Prevention (DCP).


To date, very few cancer biomarkers have been approved for clinical use in cancer detection or even scientifically validated in the laboratory. One obstacle is that certain study designs result in biospecimens that are not suitable for biomarker discovery or validation. Because creating new collections of biospecimens is expensive and time-consuming, it may be useful to aggressively leverage existing clinical and epidemiology cohort resources.


Workshop participants discussed the challenges, opportunities, and best practices related to leveraging NCI-funded projects and reconsidering designs to promote unbiased studies of biomarkers and their validation to improve early cancer detection. The best practices and alternative approaches discussed during the workshop will be incorporated into a forthcoming manuscript.


We will be continuing the conversation on using existing biospecimens for early cancer detection in an upcoming Cancer Epidemiology Matters blog post.  To receive notifications of new blog posts, subscribe to our blog's RSS feed.


For more information, including links to biospecimen resources, key publications, and the complete meeting agenda, visit the workshop webpage.
New Geographic Information Systems and Science Tools for Cancer Prevention and Control GISPortal

Have you heard about the Geographic Information Systems (GIS) and Science for Cancer Prevention and Control resources available through the NCI? Led by the Division of Cancer Control and Population Sciences' Surveillance Research Program, the GIS and Science website offers cancer researchers powerful new tools to assist in understanding the geographic patterns of cancer.

The GIS and Science website identifies and displays the geographic patterns of cancer incidence and mortality rates in the U.S. as well as trends and changes over time. A feature of the GIS and Science website is the NCI GIS Portal, which is a web-based station for researchers to access interactive mapping and visualization tools for cancer-related geo-spatial data. The portal harmonizes large, multi-dimensional datasets that include population-based cancer statistics as well as behavioral, environmental, clinical, socioeconomic, and policy data at the state and county levels.

A recent addition to the NCI GIS Portal is the Animated Historical Cancer Atlas, which is designed to visualize the historical patterns of cancer mortality in the U.S. The interactive tool allows users to animate smoothed age-adjusted death rates over time at both the national and state levels. The age-adjusted mortality rates presented in the Atlas are calculated using SEER (Surveillance, Epidemiology, and End Results) data on cancer site, gender, and Health Service Area. This resource can be particularly useful for developing hypotheses related to geo-spatial patterns of cancer incidence and mortality.  The tool also can be a building block for informing and evaluating current and future interventions and cancer control programs.

Another tool in the NCI GIS Portal is NCI Map Stories. It provides map-based explanations of incidence and mortality for a variety of cancer types allowing researchers to compare the data side by side. Additionally, a new exploratory tool, NCI GeoViewer, will enable users to construct comparative maps, graphs, and charts of cancer statistics and risk factors.  The GeoViewer is set to be released before the end of 2013.

The GIS and Science for Cancer Prevention and Control website also provides information about relevant funding opportunities, and examples of the multiple ways in which GIS technology has been applied to different types of data systems and sources.


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