Avon Foundation/NCI/The Center for Advancing Innovation Breast Cancer Start-Up Challenge
Application due date: November 29, 2013
RFA-RM-13-012
NIH Health Care Systems Collaboratory - Demonstration Projects for Pragmatic Clinical Trials Focusing on Multiple Chronic Conditions (UH2/UH3)
Application due date: December 2, 2013
Expires: December 3, 2013
RFA-CA-13-015
Cancer Detection, Diagnosis, and Treatment Technologies for Global Health (UH2/UH3)
Application due date: January 6, 2014
Expires: January 7, 2014
NCI Provocative Questions RFAs
Application due dates: January 15 and June 20, 2014
Expires: June 21, 2014
RFA-CA-13-010
Sub-Saharan African Collaborative HIV and Cancer Consortia (U54)
Application due date: January 17, 2014
Expires: January 18, 2014
RFA-HG-13-013
Interpreting Variation in Human Non-Coding Genomic Regions Using Computational Approaches and Experimental Assessment (R01)
Application due dates: January 21, 2014; January 21, 2015
Expires January 22, 2015
PAR-13-382
Analysis of Genome-Wide Gene-Environment (GxE) Interactions (R21)
Application due date: February 14, 2014
Expires: February 15, 2014
PAR-13-375
Nutrigenetics and Nutrigenomics Approaches for Nutrition Research (R01)
Application due dates: March 20, 2014; March 19, 2015; March 22, 2016
Expires: March 23, 2016
PA-13-377
PA-13-378
Research on Malignancies in the Context of HIV/AIDS (R01, R21)
Application due dates: Standard AIDS dates apply
Expires: September 8, 2016
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EGRP encourages readers to submit items of interest to Cancer Epidemiology Matters E-News. EGRP reserves the right to decide whether or not materials are appropriate for inclusion.
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Epidemiology and Genomics Research Program Division of Cancer Control and Population Sciences National Cancer Institute 9609 Medical Center Drive
4 East, MSC 9763
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EGRP Launches Searchable Online Database for Cancer Epidemiology and Genomics Researchers
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The Epidemiology and Genomics Research Program (EGRP) is excited to announce the launch of a new online resource for the research community, the Cancer Genomics and Epidemiology Navigator (CGEN). Created in response to feedback from cancer epidemiologists, CGEN is an integrated, searchable, and regularly updated knowledge base intended to facilitate epidemiologic research. It collates information derived from multiple sources into a centralized search engine. Filtering options (by cancer site, risk factors, authorship, etc.) permit users to fine-tune searches. CGEN includes linked data on:
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What Do You Think of NIH's Draft Genomic Data Sharing Policy?
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Comments Invited by November 20
On September 27, 2013, the National Institutes of Health (NIH) released a Notice in the NIH Guide for Grants and Contracts announcing that it is seeking public comments on a new draft Genomic Data Sharing (GDS) Policy. The new policy promotes sharing, for research purposes, of large-scale human and nonhuman genomic data generated from NIH-supported and NIH-conducted research. View the NIH Guide Notice.
The draft GDS Policy applies to research involving nonhuman genomic data as well as human data that are generated through array-based and high-throughput genomic technologies (e.g., SNP, whole-genome, transcriptomic, epigenomic, and gene expression data). The NIH considers broader access to such data particularly important because of the opportunities to accelerate research through the power of combining such large and information-rich datasets and making them available for re-analysis by other scientists. The draft GDS Policy is aligned with Administration priorities and a recent directive to agencies to increase public access to digital data resulting from federally-funded research.
To ensure that your comments will be considered, please submit your response to this Request for Information by 11:59 p.m. EST on November 20, 2013. Comments may be submitted using any of the following methods:
- Online
- Mail, hand delivery, or courier (for paper, disk, or CD-ROM submissions) to:
Genomic Data Sharing Policy Team
Office of Science Policy
National Institutes of Health
6705 Rockledge Drive, Suite 750
Bethesda, MD 20892.
NIH will host a webinar on the draft Policy on November 6, 2013 from 11 A.M. to 12:30 P.M. EST. The webinar will provide an overview of the draft GDS Policy and answer questions from the community. Visit the NIH GDS website to learn more about the GDS Policy, see announcements about upcoming webinars on the policy when they are posted, view FAQs, and subscribe to the NIH GDS LISTSERV.
Learn more about genomic datasets available for cancer research and the current data access request process.
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NCI Workshop Investigates Use of Existing Biospecimen Resources for Early Cancer Detection
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In an effort to improve early cancer detection by leveraging existing biospecimen resources, cancer researchers from a variety of cohort studies, HMOs, and clinical trials met on the NIH campus in Bethesda, MD, on August 28-29, 2013, to discuss re-purposing clinical and epidemiology cohort resources. The workshop, "Utilizing Existing Clinical and Population Biospecimen Resources for Discovery or Validation of Markers for Early Cancer Detection," was co-sponsored by NCI's EGRP and the Division of Cancer Prevention (DCP).
To date, very few cancer biomarkers have been approved for clinical use in cancer detection or even scientifically validated in the laboratory. One obstacle is that certain study designs result in biospecimens that are not suitable for biomarker discovery or validation. Because creating new collections of biospecimens is expensive and time-consuming, it may be useful to aggressively leverage existing clinical and epidemiology cohort resources.
Workshop participants discussed the challenges, opportunities, and best practices related to leveraging NCI-funded projects and reconsidering designs to promote unbiased studies of biomarkers and their validation to improve early cancer detection. The best practices and alternative approaches discussed during the workshop will be incorporated into a forthcoming manuscript.
We will be continuing the conversation on using existing biospecimens for early cancer detection in an upcoming Cancer Epidemiology Matters blog post. To receive notifications of new blog posts, subscribe to our blog's RSS feed.
For more information, including links to biospecimen resources, key publications, and the complete meeting agenda, visit the workshop webpage.
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New Geographic Information Systems and Science Tools for Cancer Prevention and Control |
The GIS and Science website identifies and displays the geographic patterns of cancer incidence and mortality rates in the U.S. as well as trends and changes over time. A feature of the GIS and Science website is the NCI GIS Portal, which is a web-based station for researchers to access interactive mapping and visualization tools for cancer-related geo-spatial data. The portal harmonizes large, multi-dimensional datasets that include population-based cancer statistics as well as behavioral, environmental, clinical, socioeconomic, and policy data at the state and county levels.
A recent addition to the NCI GIS Portal is the Animated Historical Cancer Atlas, which is designed to visualize the historical patterns of cancer mortality in the U.S. The interactive tool allows users to animate smoothed age-adjusted death rates over time at both the national and state levels. The age-adjusted mortality rates presented in the Atlas are calculated using SEER (Surveillance, Epidemiology, and End Results) data on cancer site, gender, and Health Service Area. This resource can be particularly useful for developing hypotheses related to geo-spatial patterns of cancer incidence and mortality. The tool also can be a building block for informing and evaluating current and future interventions and cancer control programs.
Another tool in the NCI GIS Portal is NCI Map Stories. It provides map-based explanations of incidence and mortality for a variety of cancer types allowing researchers to compare the data side by side. Additionally, a new exploratory tool, NCI GeoViewer, will enable users to construct comparative maps, graphs, and charts of cancer statistics and risk factors. The GeoViewer is set to be released before the end of 2013.
The GIS and Science for Cancer Prevention and Control website also provides information about relevant funding opportunities, and examples of the multiple ways in which GIS technology has been applied to different types of data systems and sources.
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