Catalyst Newsletter, May 2015
Funding Opportunities
In the News
FundingWatchlistFunding opportunity watchlist

MCIRCC's Funding Opportunity Watchlist highlights high-value funding opportunities available for 2015/16. If you are interested in forming or joining a team to pursue one of these opportunities, please contact MCIRCC's Proposal Development Unit (PDU) Manager at or 734-936-2754.

U.S. Special Operations Command BAA for Extramural Biomedical Research and Development
  • Requesting medical R&D, simple and effective devices and treatments for damage control and prolonged field care, and/or training/simulation for Special Forces use in extreme environments
  • $700,000 - $1,500,000 over 2 years
  • Pre-proposal Deadlines: 7/23/2015 and 11/19/2015
The MCIRCC Virtual Institute maintains the full list of funding opportunities, including NIBIB, DOD and NIH grants, as part of the Funding Opportunity Watchlist.

We strongly encourage you to bookmark or create a shortcut on your desktop to make regular log-in easy and hassle free. If you have yet to visit the site, be sure to revisit your instructional login communications or review the First Time Login Guide.

VIUse the Virtual Institute to fuel your proposal development know-how
Based on recent data-driven and anecdotal feedback, MCIRCC understands that a major priority for our membership is funding support, but locating the right funding opportunities, at the right time is not an easy task.

At the same time, federal research funding has leveled off in most fields, whereas opportunities are increasing for large-scale, team-driven research that tackles complex problems like critical care.

To help remedy these ongoing challenges and leverage potential opportunities, MCIRCC's Proposal Development Unit (PDU) has developed a Proposal Development Resource Center housed within the Virtual Institute.

This comprehensive library of resources is essentially an online extension of MCIRCC's PDU that enables 24/7 support. Whether you're looking to find funding opportunities, locate federal and U-M proposal guidance, or need to identify an expert collaborator, this is your one-stop shop providing access at the touch of a finger.

Key features designed to enhance your proposal development experience include:
  • the Funding Opportunity Watchlist that captures high-value funding opportunities for innovations in critical care and is updated on a continual basis;
  • Find Funding which outlines various internal U-M sources and external databases to help you locate funding opportunities;
  • the Proposal Development Toolbox where you can explore various federal agency and U-M proposal guides, templates, learning tools and more; and
  • more information About the Proposal Development Unit including key services offerings, capabilities and expertise.

The resource center also includes details on various collaboration tools, team science strategies, and recommended training and professional development opportunities.

We encourage you to bookmark or create a shortcut on your desktop to make regular login easy and hassle free.

If you have yet to visit the Virtual Institute to setup your user account, be sure to revisit your instructional login communications or click here to review the First Time Login Guide.

Contact with general questions or if you experience technical problems with the site.
Connect with us on LinkedIn

SepsisMayEngineering New Solutions: U-M redefines sepsis care & survival with MCIRCC's help

In Locating Sepsis, a feature article in the Winter 2015 edition of Medicine at Michigan, U-M researchers speak about their efforts to "improve sepsis treatment and research at the bedside, in the lab and on the policy level, at diagnosis and after recovery." These specialists from emergency medicine, physical therapy, computer science, information technology and engineering are working together to bring sepsis to the forefront. And MCIRCC's Critical Care Grand Challenge Sepsis Innovation Portfolio is part of this collaborative, multidisciplinary strategy.


Click here to read the full story...

Grand Challenge TBI Save the Date

HIMSS15HIMSS15: buzzwords, hot topics and the future of health IT
Last month more than 40,000 healthcare professionals flocked to Chicago for HIMSS15, the biggest health IT event of the year. MCIRCC was there to find out what's in store for the future of health IT to better align its strategic goals with marketplace realities. And HIMSS did not disappoint. Big topics included interoperability, analytics and population health.

OperationTBIOperation TBI: mission accepted on behalf of Massey Family Foundation
In mid-March, members met at MCIRCC's Ideation Lab for Operation TBI--an information and networking session--to discuss the research challenges surrounding traumatic brain injury (TBI). This was MCIRCC's first step in cultivating a TBI research community at U-M, all possible thanks to a generous gift from the Joyce and Don Massey Family Foundation.

MCIRCC salutes the achievements of it members in their pursuit of academic excellence, industry thought leadership, and initiatives of personal passion. Because together, leveraging each of our individual triumphs as team, we have the power to transform critical care medicine. If you have a recent achievement, award, or accolade to brag about contact with the details.
NeumarRobert Neumar and team receive NIH/NHBI SBIR Grant Award
Robert Neumar
Robert Neumar, MD, PhD along with a team of U-M researchers, in partnership with medical device company MC3, were awarded a $2.3 million NIH/NHLBI SBIR Phase IIb grant to advance the commercialization of the MC3 automatic perfusion system (APS) prototype, a simple-to-use, highly integrated, cardio-pulmonary support device capable of fully automated, controlled restoration of blood flow following cardiac arrest. The use of ECMO (extracorporeal membrane oxygenation) in the treatment of refractory cardiac arrest, a technique known as ECPR, has been shown to reduce central nervous system damage, improve brain function after recovery, and result in survival-to-hospital discharge rates up to 40 percent. A limiting factor for widespread adoption of ECPR is the need for a simple automatic perfusion system that is inherently safe, and provides full support with minimal operator intervention.
MeurerWilliam Meurer to receive SAEM Young Investigator Award
William Meurer

William Meurer, MD, MS has been selected to receive the 2015 Society for Academic Emergency Medicine (SAEM) Young Investigator Award. The award will be presented in May during the SAEM Annual Meeting in San Diego, CA. SAEM identifies up to three recipients for the Young Investigator Award each year. This award recognizes those SAEM members who have demonstrated commitment and achievement in research during the early stage of their academic career. The Society's core mission includes the creation of knowledge, and this award recognizes those who have achieved early success in this sphere.

BorjiginGhanbariJimo Borjigin, Hamid Ghanbari and team published in PNAS Early Edition
Hamid Ghanbari
Jimo Borjigin

A recent animal study by the Borjigin Laboratory, which included MCIRCC members Jimo Borjigin, PhD and Hamid Ghanbari, MD, MPH, found strong brain-heart connectivity just before death. The study revealed a storm of brain activity that erupts as the heart deteriorates, playing a surprising destabilizing role in heart function. According to the study, using a pharmacological blockade of the brain's electric connections to the heart during cardiac arrest may improve a patient's chances of survival. 


Click here to read the full story...

MolerFrank Moler part of NIH-funded research into therapeutic hypothermia for children
Frank Moler

Frank Moler, MD, MS was involved in a
large-scale, multicenter study that showed that emergency body cooling does not improve survival rates or reduce brain injury in infants and children with out-of-hospital cardiac arrest more than normal temperature control.

The research findings were presented at the Pediatric Academic Societies Annual Meeting in San Diego, CA and published simultaneously in the New England Journal of Medicine.

Click here to read the full story...
FuJianping Fu and Kevin Ward receive MTRAC Kickstart Award
Jianping Fu

Jianping Fu, PhD and Kevin Ward, MD propose to develop a microscale coagulation monitoring device that can continuously monitor the whole-blood clotting process in real-time, starting with fibrin formation and then continuing through to clot retraction and fibrinolysis. The project, Development of a microscale whole blood coagulation assay platform, aims to identify the cause of bleeding and guide pro- and anticoagulant therapies.

FanXudong Fan and Kevin Ward receive MTRAC Kickstart Award
Xudong Fan

Xudong Fan, PhD and Kevin Ward, MD have received funding for their project: Micro Gas Chromatography and Breathomics for Acute Point-of-Care Diagnostics

The project involves developing a small device that can be hand-held or attached to a ventilator, that is capable of continuous or intermittent monitoring of exhaled breath with a breathomic panel readout.

Exhaled breath contains volatile inorganic and organic compounds markers that can be used to predict the onset and severity of diseases and guide therapy.
SjodingMichael Sjoding to chair big data session at ATS 2015
Michael Sjoding

Michael Sjoding, MD will provide an introductory talk and moderate a critical care track on big data at the 2015 American Thoracic Society (ATS) International Conference on Tuesday, May 19.

The session will define "big data" and describe how it is being applied to improve the care for patients with critical illness in multiple domains: for real-time identification of patients at the highest risk of decompensation, as decision support for individualized patient treatment recommendations, as new tools for the study of critical illness, and as mechanisms for continuous quality improvement. Also covered will be challenges to "big data" adoption, technical hurdles and system support requirements.

Click here for more information...


Virtual Institute

Bookmark this page!
Follow us on LinkedIn

Don't forget your MCIRCC affiliation!

If you are speaking with the media about your work in critical care research or are working with the U-M News Service or U-M Health System Public Relations on a health care related press release, article, or other news item, please mention your MCIRCC affiliation!



Critical Care Grand Challenge: TBI

Friday, October 2 & Saturday, October 3 


Join us for MCIRCC's second Critical Care Grand Challenge where we will seek to use "integrated science teams" to develop and deliver technological solutions to impact traumatic brain injury (TBI) during the "golden hours." Once again, the Grand Challenge targets big problems in critical care and will reward big, bold solutions built by teams urgently working together to get these TBI solutions into the critical care ecosystem.


Click here to learn more... 

TBI Info Sheet


Two-page information sheet outlining the "TBI Challenge" and the Massey Foundation TBI Innovation Fund.

MCIRCC Sepsis Brochure

A comprehensive tool to narrate the complex and life-threatening sepsis story and how our Grand Challenge portfolio seeks to transform the way we diagnose, treat and monitor sepsis to improve patient care and outcomes, enhance the clinician experience and reduce healthcare costs.

U-M Training & Events
May 7
Conference Posters in PowerPoint
2:30 pm to 3:30 pm
Room G063, Building 10, NCRC

In this workshop, participants will learn how to use PowerPoint to create high quality, eye-catching scientific posters.

Participants will learn techniques for organizing materials, adding text, images and charts, as well as best practices on how to print posters.

Basic computer skills are required, but no prior experience with graphics applications is necessary. Regardless of the type of computer used in this session, everything covered is applicable whether you normally use a Mac or a Windows PC.

May 7
Microfluidics in Biomedical Sciences Training Program 2015 Symposium
4:00 pm to 8:00 pm
NCRC, Building 18, Dining Hall

Keynote Speaker Dr. Mike Ramsey of The University of North Carolina of Chapel Hill will discuss Micro- and Nanofabricated Molecular Measurement Devices in the Ramsey Lab: Past, Present, and Future.

May 29
Early Tech Development Course

This is a 4-week course designed to equip biomedical faculty and researchers at U-M with the knowledge and tools to navigate the initial process of innovation and commercialization.

Using a technique called Customer Discovery, teams conduct experiments and collect evidence on their technology's clinical utility, key partners, intellectual property, regulatory pathways, revenue model, and more.

Please contact Jon Servoss for more information and to register for the course.
August 20
Circle Drive in front of Med Sci I 

Join the UMMS Office of Research during the annual Ice Cream Social, with 50+ exhibitors from labs and offices of the Medical School and across campus. There will be ice cream, popcorn, games, and lots of giveaways.

U-M Center for Integrative Research in Critical Care (MCIRCC) is one of the world's first comprehensive research enterprises devoted to transforming critical care medicine by accelerating science and moving it from bench to bedside. To do this, MCIRCC brings together integrative teams comprised of world-class U-M scientists, clinicians, and engineers with industry partners and funding sources to develop and deploy cutting-edge solutions that elevate the care, outcomes, and quality of life of critically ill and injured patients and their families.