BIO Ventures for Global Health
February 2013
In This Issue
Quick Links

New WIPO Re:Search Member! 

We are pleased to announce that the
Eskitis Institute at Griffith University, in Queensland, Australia has joined WIPO Re:Search as a Provider-User Member.
Upcoming Global Health Events
What important conferences are coming in the next two months? Read more...

3rd Annual COHRED Colloquium
On 26-27 March this year, the Council on Health Research for Development (COHRED) is hosting their third COHRED Colloquium. This year's meeting is going to focus on the importance of increasing the volume and efficiency of investments in research and innovation in LMICsFind out more....

SNAPSHOT Newsletter
A Note from Jennifer
Dear WIPO Re:Search Members,

2013 has gotten off to a great start for BVGH and the Partnership Hub!  We are settled into our new Seattle offices and are co-located with the Institute for Systems Biology, a Premier nonprofit research organization based in Seattle, Washington.  Come and visit us soon!

 

WIPO Re:Search partnerships continue to be forged between member organizations to accelerate the development of new products for neglected tropical diseases.  Collaborations are taking shape in the form of hosting arrangements and compound, library and expertise sharing by WIPO Re:Search Founding members; Alnylam, AstraZeneca, Eisai, GlaxoSmithKline, Merck, Novartis, Pfizer and Sanofi.  If you have a request feel free to contact the Partnership Hub or respond to me directly.

 

We're pleased to welcome the Eskitis Institute  at Griffith University to WIPO Re:Search.  Griffith University is our first Australian member!

 

Please share this Partnership Hub Snapshot with your colleagues and send us names and contact details of any colleagues who would like to be added to our distribution list.

 

We look forward to working with you to identify collaborations to advance the development of drugs, vaccines and diagnostics for neglected tropical diseases, malaria and tuberculosis.

 

Sincerely,

 Jennifer

 

Cornerstones of Collaboration
The first anniversary of the London Declaration in support of NTD research and user-driven updates to the WIPO Re:Search database. Read more...

Partnership Hub Central
Roopa and Jennifer have been busy connecting researchers from the University of Washington, CalTech, University of Lagos in Nigeria, and others.
Read more...

Research Request
Researchers at Stanford University are seeking collaborators in leishmaniasis.  Read more...
Highlighted Contributions
University of Kansas has contributed a wide range of critical lead optimization and quantitative services into the WIPO Re:Search database. Read more... 

We've moved!

BVGH is thrilled to announce that we are settled into our new headquarters! We are now co-located with the Institute for Systems Biology in Seattle, WA.

We want to hear from you!  What do you think about the new look
of our Snapshot newsletter?
NewMember
New Member Announcements


Professor Ronald J. Quinn
Eskitis Institute Director
"We are very pleased to be the first Australian research organisation to join WIPO Re:Search and are looking forward to bringing our unique natural product expertise to new collaborations with Re:Search members," said Professor Ronald J Quinn AM, Eskitis Institute Director.

Housed within Griffith University on Australia's Gold Coast, the institute represents three unique, collaborative centres researching neurobiology, cell biology, infectious disease, natural products, and early stage drug discovery. The centres are led by Director, Dr. Ron Quinn, and hosts more than 188 researchers, students, visiting faculty, and administrative staff.

CoC
Cornerstones of Collaboration -- 2012 Partnering Highlights
BVGH and WIPO Re:Search have endorsed the London Declaration to end NTDs. Started in January 2012, the London Declaration "represents a new, coordinated push to accelerate progress toward eliminating or controlling 10 neglected tropical diseases (NTDs) by the end of the decade."   Organizations from around the world, including BVGH and WIPO Re:Search have pledged to "work together to improve the lives of the 1.4 billion people worldwide affected by NTDs, most of whom are among the world's poorest."  The first anniversary of the London Declaration was January 30, 2013. For more information, click here.

WIPO Re:Search has launched a survey to support efforts to update and improve the current online WIPO Re:Search database. All Members are encouraged to visit the web survey here to provide feedback on the current version of the database.
PHC
Partnership Hub Central
Fred Buckner (Associate Professor, Department of Medicine), University of Washington spoke with BVGH about his research to identify, select and validate compounds that target trypanosomes. BVGH is working to identify partners who can bring value to this program and help facilitate further development of these compounds.

 

Communication between faculty members at the California Institute of Technology (Caltech) with the ANDI Center of Excellence for Malaria Diagnosis at the University of Lagos, Nigeria was facilitated by BVGH. Interest in working together to develop a novel diagnostic for malaria was established. Caltech's antibody-stabilization technology will be leveraged in this potential collaboration.

 

Anacor and Pfizer Animal Health were connected to discuss how they might collaborate around onchocerciasis.

 

Progress has been made on an early WIPO Re:Search Agreement signed

Roopa meeting with Joshua Odingo, Director of Chemistry in the TB drug discovery group at Infectious Disease Research Institute (IDRI).

between AstraZeneca and UCSF. Cathepsin inhibitors provided by AstraZeneca were screened against enzyme targets and parasites at UCSF and some promising hits have been identified. Next steps in this collaboration are being determined by AstraZeneca, Jim McKerrow and Conor Caffrey from UCSF.  

 

Researchers from the Infectious Disease Research Institute (IDRI) and the Medical Research Council of South Africa and University of CapeTown will explore collaboration opportunities around anti-TB compounds developed from natural products in South Africa.

 

GALVmed's Grant Napier visited the Trypanosomiasis Research Center at the Kenyan Agricultural Research Institute (KARI) to discuss and explore collaboration opportunities with Grace Murilla, Head of the Trypanosomaisis Research Center at KARI and colleagues. The members will remain in contact and plan to work together at the right stage of product development.

HC
Highlighted Contributions
The University of Kansas (KU) Biotechnology Innovation and Optimization Center (BIO Center) supports lead optimization processes that are critical for selecting and advancing promising chemical compounds. The BIO Center is led by Dr. Michael Baltezor, a pharmaceutical industry veteran, and can characterize the physical and chemical properties of novel compounds.  The center has expertise in formulating drug products for in vivo preclinical studies and conducts pharmacokinetic and pharmacodynamic studies in rodents, dogs and non-human primates. Capabilities also include the ability to conduct limited accelerated drug product stability studies.

 

 

The Macromolecule and Vaccine Stabilization Laboratory (MVSL) within the KU Department of Pharmaceutical Chemistry specializes in the stabilization of vaccines as well as protein and DNA based pharmaceuticals. This laboratory is directed by Professor Russ Middaugh, who led the Gardasil vaccine development program while at Merck. The laboratory includes a Biosafety Level-3 (BSL-3) facility and Mass Spectrometry laboratory with MALDI-TOF and Q-TOF instrumentation.

 

These contributions were recently uploaded to the WIPO Re:Seach database . If you are interested in collaborations around these contributions please email Roopa.

ResReq  Research Request 

 

Nir Qvit, a postdoctoral researcher at Stanford University is interested in accessing expertise in peptide formulations for an inhibitor of cutaneous leishmaniasis. The inhibitor has demonstrated efficacy in an animal model. 

 

If you are interested in learning more about this research request, please email Roopa.

EventsTable
Upcoming Global Health Events

Dates

Event Title

Location

Web Link

13-18
MARCH

Keystone Symposium on Tuberculosis  

 Whistler, B.C.  

  Link 

14-16 MARCH  

4th Annual CUGH Conference on Global Health: Innovation, Implementation, Impact  

Washington, DC 

Link 

24-27
MARCH
3rd Global Forum on TB Vaccines
Cape Town,
South Africa
Link
26-27
MARCH
COHRED Colloquium 2013
Geneva, Switzerland
Link









Are you attending a global health event? Do you have a Research Request to highlight in the Snapshot?
We want to hear from you! Please send feedback and suggestions via email.




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