DUKE UROLOGY E-NEWS
Glenn M. Preminger, MD
James F. Glenn, MD Professor of Urology
Chief, Division of Urologic Surgery
Spring has finally arrived in Durham! After one of the coldest months of March, the flowers and trees are finally in bloom and the weather has warmed considerably. There has also been a spring awakening of the Duke University Medical Center, with the opening of the new Trent Semans Center for Health Education. This is the first new home for Duke medical student education since classes began in the Davison Building in 1930. http://construction.dukemedicine.org/projects/som-learning-center. The majority of construction has also been completed on the new Duke Medicine Pavilion, a major expansion of Duke University Hospital. One hundred and sixty (160) critical care beds and eighteen (18) new operating rooms are expected to be open to patients and families in July 2013. http://construction.dukemedicine.org/projects/duke-medicine-pavilion. The Duke Cancer Center has been open for a little over a year, providing a new home for our Urologic Oncology patients and faculty. http://www.dukehealth.org/cancer/locations/duke-cancer-center. This major transformation of the Duke Health campus in Durham ensures modern, state-of-the-art facilities for Duke Urology as we continue to pursue our missions of patient care, research and education.
This has proven to be a particularly busy and productive winter and spring for Duke Urology. We welcome Matthew O. Fraser, Ph.D., as our new Director of Urology Basic Science Research. Matt brings a wealth of experience in translational research for bladder physiology and new drug development for overactive bladder problems. His innovative approach to bladder physiology has already garnered a number of grants and awards for bladder research. In fact, Nicholas Kuntz, MD, one of our PG3 Residents working in Dr. Fraser's laboratory, recently won the James C. Kimbrough Memorial Award for Basic Science Research based on their work entitled, "Dose-Dependency of Radiation Cystitis in a Rat Model: Repeat Cystometric Evaluation with Saline Alone and KC1 Challenge."
Our clinical practices in Durham and Raleigh continue to thrive. Drs. Mike Lipkin and Aaron Lentz provide updates on our clinical activities in the Duke Urology Clinic in Durham and Duke Urology of Raleigh, respectively. Our clinical volumes continue to grow in all three practice locations, including the Urologic Oncology Clinic in the new Duke Cancer Center. In addition, our educational programs have been well received, not only at Duke but by the urologic community at large. The strong attendance at our 45th Duke Urologic Assembly meeting in Orlando, Florida was proof that the diverse curriculum provided an extensive overview of urologic practice. Guest faculty included Peter Carroll, MD from UCSF, as well as a previous Duke faculty member, David Albala, MD and former Duke Urology Chief, David Paulson, MD. Our most recent Duke Tuesday in Urology conference in February accommodated over 100 attendees who came to hear Shlomo Raz, MD from UCLA, mentor of our new faculty member, Nikki Le, MD.
Dr. John Wiener provides an update of our numerous Urology CME activities both locally and nationally. Please consider participating in an upcoming Duke Tuesday event in Durham or come to Pinehurst in April 2014 to attend the Duke Urologic Assembly.
Our research efforts continue to expand. Drs. Brant Inman, Sherry Ross and Jon Routh provide a synopsis of various research efforts and accomplishments over the last six months.
In our DYSURIA segment for this newsletter, we highlight Dr. Albert Ruenes, Jr. who continues to teach the technique of radical perineal prostatectomy that he learned as a Duke Resident in the 1990's. In addition to Al's charitable efforts, Duke Urology has been involved in medical missions to Haiti and Guatemala. Drs. Drew Peterson and Sherry Ross provide a synopsis of these humanitarian endeavors.
|Dr. Albert Ruenes, Jr. with Dr. Preminger at the SIU meeting in Fukuoka, Japan, Sept. 30 - Oct. 4, 2012|
Duke Urology also participated in the annual Movember Movement (http://us.movember.com.about) to help raise funds and bring awareness to men's health issues. The team, led by Dr. Michael A. Granieri (PGY-2) and virtually all of our male house staff and faculty, grew moustaches to show their support and helped raise approximately $1,000 for this effort. To view the local news video of Duke Urology's Movember team go to http://abclocal.go.com/wtvd/video?id=8892798.
|Duke Urology's Movember Team|
We are all busy preparing for the AUA annual meeting in May, where Duke Urology will have a strong showing with podium and poster presentations, along with faculty members leading various post-graduate courses. Please attend our annual DYSURIA Cocktail Reception to be held on Saturday evening, May 4th. And as always, if you are in the area, please stop in for a visit. I would love to show you what's going on at Duke Urology.
All the best,
Matthew O. Fraser, Ph.D.
Dr. Fraser holds a dual-degree PhD in Physiology and Neuroscience. In addition to his academic career, he spent seven years in the pharmaceutical industry during which time he developed therapeutics for the treatment of pelvic visceral dysfunction. He has been awarded nine patents and currently has thirty-three published patent applications. Dr. Fraser's research interests have historically included pelvic visceral sensory and motor function and dysfunction with a primary focus on the lower urinary tract. As part of Duke Urology's faculty team, Dr. Fraser will develop a research effort dedicated to translational research with a focus on bladder physiology studies.
Michael E. Lipkin, MD
Clinical Operations - Duke South
Clinic 1G continues to grow and succeed. Over the past several months, the clinic has brought on several new staff members while collecting accolades from the health system. The clinic recently had the highest patient satisfaction score for all DUH clinics. Urodynamics was named the top clinic performer in the month of November.
The plans are for continued growth and excellence. There is an active search for a new nurse manager. In August, the clinic will be adding another faculty provider. In addition, work is ongoing in preparation for our conversion to Maestro in June.
Aaron C. Lentz, MD
Duke Urology of Raleigh Clinical Operations
After a successful first year, Duke Urology of Raleigh continues to offer cutting edge urologic care to the citizens of Wake County and eastern North Carolina. Headlining our effort in year two is the addition of a full-time resident to the Duke Raleigh team. Since July 1st, 2012, each PGY-2 resident has spent 3 months rotating through the OR's and clinics of Duke Raleigh Hospital. During the rotation, residents are exposed to a wide assortment of benign and malignant urologic diseases as well as robotic, laparoscopic, and endourologic approaches to treatment. The abundance of great operative cases is complimented by the opportunity to actively participate in busy clinics, multidisciplinary approaches to care, and office based procedures. The addition of a talented resident to the Raleigh practice has been an unbridled success and continues the Duke mission of world-class urologic education.
The Duke Raleigh practice also welcomed a new member in September, when Dr. Nikki Le held her first satellite clinic. Dr. Le provides cutting edge care in pelvic floor reconstruction, specializing in urinary incontinence, voiding dysfunction, and mesh-less repairs for pelvic organ prolapse. Dr. Le is the only urologist in Wake County to have completed a 2-year accredited fellowship in female urology and we are excited to have her expertise in Raleigh.
As the Raleigh practice continues to grow, we are constantly working to improve access to care and deliver on the Duke values of excellence, safety, integrity, diversity, and teamwork. These core values are at the root of our early success and provide a steady platform for new challenges that lie ahead.
John S. Wiener, MD
The 45th Duke Urologic Assembly was held at the Grand Floridian Conference Center at Walt Disney World in Orlando, January 24-27, 2013. Twelve Duke Faculty members and three guest faculty speakers presented 20 hours of lectures covering the entire breadth of urology. Peter R. Carroll, MD, MPH of UCSF gave the annual Victor A. Politano Lecture, "PSA for the Early Detection and Treatment of Prostate Cancer in the US: Always, Never or Only Sometimes", which was followed by a luncheon honoring Dr. Politano's legacy. The oncology sessions that morning were moderated by former Chief of Duke Urology, David F. Paulson, M.D. Attendance was strong this year with sixty urologists and twelve other learners (midlevel providers and residents) in attendance and hailing from twenty-three states.
Pictured left to right: David Paulson, Peter Carroll, Glenn Preminger and David Albala
The Duke Urologic Assembly will return to its roots in 2014 and be held at the Pinehurst Inn for the first time since the 1980's. It is not coincidental that the U.S. Open Men's and Women's Golf Championships will both be held at Pinehurst during this time. Please make plans to join us April 3-6 of next year.
The Duke Tuesday in Urology conference series remains a strong educational tradition for both residents and practicing urologists. Dr. Shlomo Raz of UCLA returned as a visiting professor for the second time on February 19, 2013; he had previously visited Duke over twenty years ago. Dr. Raz gave the annual John E. Dees Lecture on "Anatomy of Incontinence and Complications of Mesh". In addition to other Duke Faculty speakers presenting that day, new faculty member Nikki Le, MD who came to Duke last year after completing a fellowship in female pelvic medicine and reconstructive urology with Dr. Raz, presented "Life After Anti-Muscarinics: Treatment Options for Refractory Idiopathic Overactive Bladder."
|(left to right): Nikki Le, Shlomo Raz, Drew Peterson and Glenn Preminger|
This CME-accredited conference is held three times a year and it continues to draw urologists from the tri-state regions of N.C., S.C. and Virginia with an average attendance of 100. The upcoming July 23rd Duke Tuesday Guest Faculty speaker will be Thomas W. Jarrett, MD, Chair of Urology at George Washington University, who will give the Morris Center for Research Lecture. Guest lecturer for the November 12th Duke Tuesday will be Dean G. Assimos, MD, Chair of Urology at the University of Alabama-Birmingham.
Brant A. Inman, MD, MS
Adult Urology Research
In the past year Duke Urology has published over 180 research related manuscripts in a wide array of high quality medical journals. These publications cover all aspects of urology including oncology (over 130 manuscripts), endourology (20 manuscripts), pediatrics (17 manuscripts), and reconstruction (12 manuscripts). They include clinical trials, basic science, translational science, and health services and outcomes research. Several of our research projects have won awards at regional, national, and international meetings, reflecting the outstanding quality of research currently being done at Duke.
Innovation is another feature of the research being conducted by Duke Urology. In the past year, we have been awarded several research grants and awards for innovative ideas on the cutting edge of urology. Additionally, collaboration with a diverse group of researchers (biomedical engineers, industrial engineers, medical physicists, geneticists, nutritionists, and biochemists) has led to several innovations, including:
- novel diagnostic tests and treatment approaches for cancer
- new understanding of the impact of diet and exercise on cancer development and outcome
- new understanding of pediatric urolithiasis
- new methods of administering shock wave lithotripsy
- new animal model for genitourinary radiation toxicity
- new animal model for bladder cancer hyperthermia treatment
- new animal model for UTIs and spinal cord injury
In summary, 2012 was a fantastic year for Duke Urology. Our research portfolio continues to grow and our recruitment of new faculty members, several of whom have significant research appointments, will ensure our success going forward into 2013.
Sherry S. Ross, MD
Pediatric Urology Research
Research in the section of Duke Pediatric Urology continues to move forward and grow with exciting research in basic science, outcomes and clinical research. Dr. Rajeev Chaudhry, a 4th year Duke Urology resident spent his research year under the mentorship of Dr. Sherry Ross and Dr. Patrick Seed who directly supervised and mentored Dr. Chaudhry in the laboratory. During this time, Dr. Chaudhry discovered a profound difference in the levels of inflammatory markers of rats after spinal cord injury and significantly blunted inflammatory response after 24 hours of infection when compared to sham controls. His work titled "Inflammatory Response to Escherichia Coli Urinary Tract Infection In the Neurogenic Bladder of the Spinal Cord-Injured (SCI) Host" won 3rd place in basic science at the 2012 American Academy of Pediatrics meeting, was awarded 1st place at the Grandover Resident Retreat and was awarded second place in the Montague L. Boyd Essay competition at the Southeast Section of the American Urological Association meeting in Williamsburg, Virginia. Currently our work is ongoing with Drs. Ross and Seed mentoring Dr. Ramiro (Joe) Madden-Fuentes, a 3rd year Urology resident, as we continue to better understand infections in the neurogenic bladder. Drs. Ross, Wiener and Routh, in conjunction with our colleagues Dr. Stephen Freedland, Dr. Glenn Preminger and Dr. Michael Lipkin, reported our results evaluating the influence of diet on urine analytes that predispose to stone disease in a pediatric mouse model. We found that western diets, particularly those high in sodium and fructose, resulted in a stone promoting environment. While this was a small pilot study, it suggests that diet may play a large role in the increasing incidence of stone disease in children. The manuscript will be available in the December edition of the Journal of Urology.
Dr. Jon Routh is continuing his efforts to better understand urologic diseases in children through outcomes research efforts. Dr. Routh, along with Dr. Jessica Lloyd, a 3rd year Urology resident, has worked very hard this year on multiple projects. Recently, they performed a systematic review of the literature to determine the definition of urinary continence in patients with Spina Bifida. Interestingly, the most frequent definition of urinary continence in the spina bifida literature was "always dry". However, definitions were highly variable, and many authors did not define continence at all. Based on this research, they concluded that clinicians and researchers alike would be better able to apply research findings toward improving patient care if continence definitions were more explicitly reported and less variable. Their report titled "Reviewing definitions of urinary continence in the contemporary spina bifida literature: A call for clarity" was recently accepted for publication in the Journal of Pediatric Urology. We are very proud to report that Dr. Routh and Dr. Lloyd will represent Duke Pediatric Urology at the American Urological Association in San Diego as they present their work, "Does Regional Variation in Bladder Augmentation Rates Correlate with Variation in Renal Outcomes among Children with Spina Bifida."
Dr. John Wiener continues to move forward on the clinical research front. Completion of year one for enrollment in the National Spina Bifida Registry was very successful. With team effort we surpassed the required number to meet our enrollment goals. We are moving into the second phase of the registry and expect the same level of successful enrollment. Similarly, the CAKUT (Congenital Abnormalities of the Kidney and Urinary Tract) is now enrolling patients. This will be a very important study to evaluate the genetic profiles of patients and families with urinary tract abnormalities. Enrollment has just started but families are very receptive and eager to participate. We expect exciting outcomes at study end. Recently, Dr. Wiener published a very important case report documenting the first known case of symptomatic, bilateral long-term obstruction in a child treated for vesicoureteral reflux with Deflux. This is a sentinel case report since some pediatric urologists do not follow children with imaging after treatment. While rare, this report demonstrates the devastating effects of missed obstruction of the ureters after treatment and will prompt a potential change in follow-up by many pediatric urologists as they become aware of this rare but very real complication.
Jonathan C. Routh, MD, MPH
Database & Outcomes Research
The Duke Urology clinical research databases continue to be a tremendous scientific resource for the division. In the last 6 months, we have reinforced our longstanding collaborative relationships with industry and with other institutions based on the strengths of the DPC & SEARCH database models. Among recent publications, several have received significant media attention, including a BJU International paper from SEARCH examining diabetes as an effect modifier of metastatic risk in obese men after prostatectomy.
Over the last year, Duke Urology has fundamentally re-examined the way that we gather and process data. Under the leadership of our Duke and VA database managers, Leah Gerber and Robert Kundich, data-gathering and database management is in the process of becoming a much more automated process - one that is both more accurate and faster than more traditional "elbow grease" methods. This will allow us to gather clinical data - including quality-improvement data - in real time, so that clinical issues can be detected and addressed quickly.
In addition to the clinical benefits, this shift will allow us to expand our database research into areas beyond traditional strengths such as oncology - essentially allowing us to diversify our research portfolio. We are particularly excited regarding ongoing efforts in reconstruction, endourology, and pediatrics, all of which have significant potential to produce highly significant research in the near future.
Former Duke Urology Resident Teaches Minimally Invasive RPP
to African Urologists
In June 2004 the first radical perineal prostatectomy (RPP) was performed at Hopital General de Grand-Yoff in Dakar, Senegal as the start of what would grow into a formal training program to teach minimally invasive radical prostatectomy in a region of the world where prostate cancer has been termed a "malignant epidemic".
Albert Ruenes, Jr., MD met Professor Serigne Gueye while the Senegalese urologist was working with geneticists at the University of Pennsylvania Hospital. Professor Gueye travelled to Doylestown, Pennsylvania where Dr. Ruenes practices with Drs. Steven Flashner, Kevin Fitzgerald and Frank Roland at Central Bucks Urology. Taking a break from his genetics research at the university, Professor Gueye observed Dr. Ruenes perform a RPP at Doylestown Hospital. He had never before seen the operation but felt it was uniquely well suited to the treatment of prostate cancer in West Africa. He invited Dr. Ruenes to Dakar to teach the procedure to urologists visiting from several West African nations. Since that initial symposium Dr. Ruenes has made annual trips to Senegal to advance his efforts there. The procedure is now being performed independently at the Hopital General de Grand-Yoff by its staff urologists.
The America Senegal Surgical Initiative - Surgeons Teaching Surgeons (ASSISTS) www.assists.us.com was founded to support Dr. Ruenes' work in West Africa. A fundraiser was held in Bucks County, Pennsylvania in May 2011. Dr. David Paulson, former Chief of Urology at Duke, attended the event and was recognized for his contribution to the program, having served as Dr. Ruenes' mentor. It is indeed part of Dr. Paulson's legacy that radical perineal prostatectomy is now performed in Dakar, Senegal.
Dr. Ruenes, who completed his Urologic Surgery residency at Duke in 1994, teaches African urologists how to perform RPP surgery
The ultimate goal of Dr. Ruenes' teaching program is to establish a center of excellence where surgeons from throughout Africa can travel to learn radical perineal prostatectomy from other African surgeons. To help realize this goal, future instructional programs will be scheduled in Dakar. A select few West African surgeons will be chosen for the most intense training and with adequate financial support a surgeon-in-residence program can be established to provide continuous training for months at a time.
Tax Deductible Contributions to the DYSURIA program are welcomed and should be made payable to:
c/o DUKE UROLOGY ADMINISTRATION
DIVISION OF UROLOGIC SURGERY
DUKE UNIVERSITY MEDICAL CENTER
DURHAM, NC 27710
DUKE UROLOGY SUPPORTS MEDICAL HUMANITARIAN MISSIONS
IN HAITI AND GUATEMALA
The Duke Urology section of Reconstructive Urology performed the first international urological surgery/ humanitarian medical mission to Haiti from August 30 to September 5, 2012. During this time Dr. Drew Peterson and his team, Dr. Erin McNamara (genitourinary cancer survivorship fellow) and Dr. Danielle Stackhouse (reconstruction fellow) performed multiple complex urethroplasty reconstructive surgeries in conjunction with local Haitian urologists. The Duke team was also joined by teams from Washington University in St. Louis, Florida International University and the University of Miami.
Pictured left to right: Drs. McNamara, Stackhouse and Peterson
Hosted by the Association of Haitian Urologists, the Duke surgeons worked at two separate hospitals, University Hospital and the Petion-Ville Hospital in Port-au-Prince, Haiti. In addition to performing these incredibly needed complex reconstructive procedures, the team also gave lectures for the urology residents, didactic instruction sessions and practical hands-on instruction for the staff urologists as well as professional interaction and consultation for implementation of new systems and procedures within this austere medical system.
The medical mission was supported by grant through the society of Genitourinary Reconstructive Surgeons (GURS) of which Dr. Peterson is a member of the Board of Directors. Missions such as this are planned to take place regularly in order to increase the teamwork, collaboration and surgical education between American and Haitian urologists during the rebuilding of their country.
In April of 2012, Dr. Henry Rice of Duke Pediatric General Surgery and Dr. Sherry Ross of Duke Pediatric Urology partnered with Mending Kids International and the Shalom Foundation to head a 14-member team of Duke Medicine volunteers to Guatemala City, Guatemala to perform surgery on dozens of children with multiple general and urological surgical conditions. During the 7-day trip, despite the challenges of a new working environment with limited equipment, the group performed 48 surgeries. The team implemented the same standard of care provided to children who undergo surgery at Duke. This resulted in an optimal outcome for all Guatemalan children who underwent surgical intervention. The Duke team partnered with local Guatemalan surgeons not only to help in the care of the children but also to build a long-lasting collaboration to enhance the local health care system.
Dr. Ross (right) performs surgery on Guatemalan child
In addition, Drs. Rice and Ross met with the Dean of the Universidad Francisco Marroquinlocal Medical School, pediatric residents from the Universidad de San Carlos de Guatemala and local Guatemalan pediatric surgeons where Drs. Rice and Ross discussed educational exchange opportunities, gave lectures on clinical and research topics and discussed challenging surgical cases. The mission trip was a great success in terms of patient care, education, collaboration and research opportunity. Drs. Rice and Ross are currently planning a second mission trip in August of 2013.
DUKE UROLOGY RESIDENCY TRAINING PROGRAM
John G. Mancini, MD
Suzanne B. Stewart, MD
Brian M. Whitley, MD
Senior Residents (PGY-5):
Mark R. Anderson, MD
Zarine R. Balsara, MD, PhD
David I. Chu, MD
Senior Residents (PGY-4):
Rajeev Chaudhry, MD
Zachariah G. Goldsmith, MD, PhD
Abhay A. Singh, MD
Laboratory Residents (PGY-3):
Jessica C. Lloyd, MD
Ramiro Madden-Fuentes, MD
Nicholas Kuntz, MD
Junior Residents (PGY-2):
Michael A. Granieri, MD
Richard H. Shin, MD
Tara Ortiz, MD
Hsin-Hsiao Wang, MD
Duke Urology Presentations at the 77th Annual Meeting of the Southeastern Section of the American Urological Association (SESAUA) held in Williamsburg, Virginia, March 14 - 17, 2013
OBESITY TRIPLES THE RADIATION EXPOSURE OF STONE PROTOCOL CT.
Andreas Neisius, Agnes Wang, Gaston Astroza, Zachariah Goldsmith, Chu Wang, Gia Nguyen, Nicholas Kuntz, Muhammad Iqbal*, Michael Ferrandino, Amy Neville, Carolyn Lowry, Greta Tonchewa, Terry Yoshizumi, Glenn Preminger and Michael Lipkin.
OPTICAL PERFORMANCE COMPARISON OF DEFLECTABLE LAPAROSCOPES FOR LAPAROENDOSCOPIC SINGLE-SITE (LESS) SURGERY.
Zachariah Goldsmith, Gaston Astroza, Andreas Neisius, Agnes Wang, W. Neal Simmons, Muhammad Iqbal, Ramy Youssef Yaacoub, Nicholas Kuntz*, Michael Lipkin, Glenn Preminger and Michael Ferrandino.
DEVELOPMENT AND VALIDATION OF A MULTIVARIATE MODEL COMBINING CELL CYCLE PROGRESSION SCORE WITH CAPRA TO PREDICT PROSTATE CANCER MORTALITY IN A CONSERVATIVELY MANAGED COHORT.
Michael Brawer*, Matthew Cooperberg, Stephen Freedland, Gregory Swanson, Steve Stone, Julia Reid, Alexander Gutin, Peter Carroll and Jack Cuzick.
IS ADULT HEIGHT A RISK FACTOR FOR BIOCHEMICAL RECURRENCE AFTER RADICAL PROSTATECTOMY? RESULTS FROM THE DUKE PROSTATE CENTER.
Abhay Singh*, Judd Moul, Cagri Senocak, Leah Gerber, Cary Robertson, Thomas Polascik, Philip Walther and Lionel Baņez.
STONE FACTORS PREDICTING STONE FREE RATES IN PERCUTANEOUS NEPHROLITHOTOMY.
Gaston Astroza, Andreas Neisius, Agnes Wang, Zachariah Goldsmith, Nicholas Kuntz, Muhammad Iqbal*, Ramy Youssef Yaacoub, Lionel Baņez, Leah Gerber, Michael Ferrandino, Michael Lipkin and Glenn Preminger.
DRAMATIC EFFECTS OF A SELECTIVE BETA3-ADRENERGIC AGONIST ON INDICES OF NEUROGENIC DETRUSOR OVERACTIVITY ASSOCIATED WITH SUPRASACRAL SPINAL CORD INJURY.
Danielle Stackhouse*, Paul Dolber, Andrew Peterson and Matthew Fraser.
REMARKABLE DOSE-DEPENDENCY OF RADIATION CYSTITIS IN A RAT MODEL: REPEAT CYSTOMETRIC EVALUATION WITH SALINE ALONE AND POTASSIUM CHLORIDE CHALLENGE.
Nicholas Kuntz*, Matthew Fraser, Marcia Bentz, Abhay Singh, Paul Dolber
and Andrew Peterson.
WHAT IS THE ANTIBIOTIC OF CHOICE FOR OBSTRUCTING STONE PATIENTS WITH SEPSIS? A CONDITION-SPECIFIC ANTIBIOGRAM.
Zachariah Goldsmith*, Olugbemisola Oredein-McCoy, Leah Gerber, Agnes Wang, Muhammad Iqbal, Gaston Astroza, Andreas Neisius, Ramy Youssef Yaacoub, Nicholas Kuntz, Luke Chen, Glenn Preminger and Michael Lipkin.
EMERGENT URETERAL STENT VERSUS NEPHROSTOMY FOR OBSTRUCTIVE UROLITHIASIS WITH SEPSIS: UTLIZATION AND OUTCOMES FROM A 15-YEAR EXPERIENCE.
Zachariah Goldsmith*, Olugbemisola Oredein-McCoy, Andreas Neisius, Gaston Astroza, Leah Gerber, Lionel Baņez, David Sopko, Michael Miller, Ramy Youssef Yaacoub, Nicholas Kuntz, Glenn Preminger and Michael Lipkin.
HEART RATE VARIABILITY (HRV) DERIVED MARKER OF SENSATION DURING PHYSIOLOGICAL BLADDER FILLING IN OAB.
Xavier Preud'homme*, Danielle Stackhouse, Joshua Lohri, Cindy Amundsen, Andrew Peterson, George Webster and Adrew Krystal.
NOCTURIA IN SUBJECTS WITH OVERACTIVE BLADDER SYNDROME (OAB): WHAT WAKES THEM UP?
Xavier Preud'homme*, Danielle Stackhouse, Joshua Lohri, Cindy Amundsen, Andrew Peterson, George Webster and Adrew Krystal.
DYSREGULATION OF INFLAMMATORY RESPONSE TO ESCHERICHIA COLI URINARY TRACT INFECTION IN THE NEUROGENIC BLADDER (NB) OF THE SPINAL CORD-INJURED (SCI) RAT.
Rajeev Chaudhry*, Zarine Balsara, Yuping Tang, Unwana Nseyo, John Wiener, Sherry Ross and Patrick Seed.
INCREASING DWELL TIME OF MITOMYCIN C IN THE UPPER TRACT WITH A REVERSE THERMOSENSITIVE POLYMER.
Zachariah Goldsmith, Agnes Wang, Andreas Neisius, Gaston Astroza, Olugbemisola McCoy, Muhammad Iqbal, W. Neal Simmons, John Madden, Ramy Youssef Yaacoub*, Nicholas Kuntz, Glenn Preminger, Brant Inman, Michael Lipkin and Michael Ferrandino.
THE EFFECT OF DIETARY SODIUM AND FRUCTOSE INTAKE ON URINE AND SERUM PARAMETERS OF STONE FORMATION IN A PEDIATRIC MOUSE MODEL.
Elizabeth Masko*, Michael Lipkin, Michael Abern, Emma Allott, Jonathan Routh, John Wiener, Glenn Preminger and Sherry Ross.
CONTEMPORARY EPIDEMIOLOGY OF COMPLEX GENITOURINARY DEFECTS.
Jessica Lloyd*, Brant Inman, Patricio Gargollo, Sherry Ross, John Wiener
and Jonathan Routh.
URODYNAMICS DOES NOT PREDICT RISK FOR RECURRENT URINARY TRACT INFECTION WITH SPINA BIFIDA AND NEUROGENIC BLADDER: AN ANALYSIS OF PREDICTIVE FACTORS.
Rajeev Chaudry*, Unwana Nseyo, Zarine Balsara, Ramiro Madden-Fuentes, John Wiener, Jonathan Routh, Patrick Seed and Sherry Ross.
EXTENDING THE ACADEMIC RANKING SCORE TO PEDIATRIC UROLOGY: QUANTIFYING THOUGHT LEADERSHIP WITHIN THE SUBSPECIALTY.
Ramiro Madden-Fuentes*, Jessica Lloyd, Sherry Ross, John Wiener, Alexander Kutikov and Jonathan Routh.
Congratulations to Resident's Jessica Lloyd and Rajeev Chaudhry who were tied for second place in the SESAUA's Montague L. Boyd Essay competition. In addition, Zarine Balsara, who won first prize as a discussant in the T. Leon Howard Pyelogram Hour, was also selected as part of a team to represent the SESAUA at the Resident's Urology Bowl during the AUA annual meeting in San Diego.
The 108th American Urological Association (AUA) Annual Meeting will be held in San Diego, May 4 - 8, 2013. To view or print a listing of Duke Urology presentations, please click on the following link:
While at the AUA, don't forget to join us for the DYSURIA reception to be held in the Leucadia Room at the San Diego Marriott Marquis from 6:30 - 8:30 pm on Saturday, May 4th.
RECENT PUBLICATIONS FROM DUKE UROLOGY
Tsivian M, Abern MR, Polascik TJ.
Evolution of the concept of focal therapy for prostate cancer.
Oncology 27(1): 1-8, January 2013.
Grant DJ, Hoyo C, Oliver SD, Gerber L, Shuler K, Calloway E, Gaines AR, McPhail M, Livingston JN, Richardson RM, Schildkraut JM, Freedland SJ.
Association of uridine diphosphate-glucuronosyltransferase 2B gene variants with serum glucuronide levels and prostate cancer risk.
Genet Test Mol Biomarkers 17(1): 3-9, January 2013.
Allott EH, Freedland SJ.
Words of wisdom: Re: Impact of circulating cholesterol levels on growth and intratumoral androgen concentration of prostate tumors.
Eur Urol 63(1): 178-179, January 2013.
Osmond GW, Masko EM, Tyler DS, Freedland SJ, Pizzo S.
In vitro and in vivo evaluation of resveratrol and 3,5-dihydroxy-4'-acetoxy-trans-stilbene in the treatment of human prostate carcinoma and melanoma.
J Surg Res 179(1): e141-148, January 2013.
Nseyo U, Mancini JG, Wiener JS.
Sympotomatic bilateral delayed partial ureteral obstruction after bilateral endoscopic correction of vesicoureteral reflux with dextranomer/hyaluronic acid polymer.
Urology 81(1): 184-187, January 2013.
Abern MR, Freedland SJ.
Prostate Cancer Antigen 3 to select men for prostate biopsy: Stop, go, or Proceed with caution?
Eur Urol 63(2): 210-213, February 2013.
Saylor PJ, Armstrong AJ, Fizazi K, Freedland S, Saad F, Smith MR, Tombal B, Pienta K.
New and emerging therapies for bone metastases in genitourinary cancers.
Eur Urol 63(2): 309-320, February 2013.
Ukimura O, Coleman JA, de la Taille A, Emberton M, Epstein JI, Freedland SJ, Giannarini G, Kibel AS, Montironi R, Ploussard G, Roobol MJ, Scattoni V.
Contemporary role of systematic prostate biopsies: Indications, techniques, and implications for patient care.
Eur Urol 63(2): 214-230, February 2013.
Abern MR, Freedland SJ, Inman BA.
Obesity is associated with worse oncological outcomes in patients treated with radical cystectomy.
BJU Int 111(2): 187-188, February 2013.
Lipkin ME, Preminger GM.
Imaging techniques for stone disease and methods for reducing radiation exposure.
Urol Clin North Am 40(1): 47-57, February 2013.
Chu DI, Balsara ZR, Routh JC, Ross SS, Wiener JS.
Experience with glycerin for antegrade continence enema in patients with neurogenic bowel.
J Urol 189(2): 690-693, February 2013.
Kokorowski PJ, Routh JC, Nelson CP.
Quality assessment of economic analyses in pediatric urology.
Urology 81(2): 263-268, February 2013.
J Urol 189(2): 669-670, February 2013.
Commentary to 'Selective endoscopic treatment of the non-refluxing contralateral ureter prevents new contralateral vesicoureteral reflux'.
J Pediatr Urol 9(1): 55-56, February 2013.
Routh JC, Yu RN, Kozinn SI, Nguyen HT, Borer JG.
Urological complications and vesicoureteral reflux following pediatric kidney transplantation.
J Urol 189(3): 1071-1076, March 2013.
Abern MR, Bassett MR, Tsivian M, Baņez LL, Polascik TJ, Ferrandino MN, Robertson CN, Freedland SJ, Moul JW.
Race is associated with discontinuation of active surveillance of low-risk prostate cancer: Results from the Duke Prostate Center.
Prostate Cancer Prostatic Dis. 16(1): 85-90, March 2013.
Dietrich D, Hasinger O, Baņez LL, Sun L, van Leenders GJ, Wheeler TM, Bangma CH, Wernert N, Perner S, Freedland SJ, Corman JM, Ittmann MM, Lark AL, Madden JF, Hartmann A, Schatz P, Kristiansen G.
Development and clinical validation of a real-time PCR assay for PITX2 DNA methylation to predict prostate-specific antigen recurrence in prostate cancer patients following radical prostatectomy.
J Mol Diagn 15(2): 270-279, March 2013.
Tsivian M, Baņez LL, Keto CJ, Abern MR, Qi P, Gerber L, Moul JW, Polascik TJ.
African-American men with low-grade prostate cancer have higher tumor burdens: Results from the Duke Prostate Center.
Prostate Cancer Prostatic Dis. 16(1): 91-94, March 2013.
Kimura M, Baņez LL, Polascik TJ, Bernal RM, Gerber L, Robertson CN, Donatucci CF, Moul JW.
Sexual bother and function after radical prostatectomy: Predictors of sexual bother recovery in men despite persistent post-operative sexual dysfunction.
Andrology 1(2): 256-261, March 2013.
Fu Q, Moul JW, Baņez L, Sun L, Mouraviev V, Xie D, Polascik TJ.
Preoperative predictors of pathologic stage T2a and pathologic Gleason score < 6 in men with clinical low-risk prostate cancer treated with radical prostatectomy: Reference for active surveillance.
Med Oncol 30(1): 326, March 2013.
Rajeev Chaudhry, Zarine Balsara, Yuping Tang, Unwana Nseyo.
AM Inflammatory Response to Escherichia Coli Urinary Tract Infection In the Neurogenic Bladder of the Spinal Cord-Injured (SCI) Host.
Third place winner in basic science at the American Academy of Pediatrics (AAP) National Conference in New Orleans, October 20-23, 2012.
Dr. Sherry S. Ross pictured here with Dr. Rajeev Chaudhry at the AAP National Conference
Percutaneous Management of UPJ Stone with UPJ Obstruction versus Robotic Reconstruction.
Vasovasostomy versus Sperm Aspiration.
Debate session winners at the 12th Annual North Carolina Urology Residents Retreat, November 3, 2012.
Inflammatory Response to E. coli Urinary Tract Infection in the Neurogenic Bladder of the Spinal Cord Injured Host.
Increasing Dwell Time of Mitomycin C in the Upper Tract with a Reverse Thermosensetive Polymer.
Research paper awards at the 12th Annual North Carolina Urology Residents Retreat November 3, 2012.
Dose-Dependency of Radiation Cystitis in a Rat Model: Repeat Cystometric Evaluation with Saline Alone and KC1 Challenge.
James C. Kimbrough Memorial Award for Basic Science Research at the 60th Annual Society of Government Service Urologists seminar held in Hawaii, January 20-25, 2013.
SAVE THE DATES
5/4/2013 - DYSURIA reception at the AUA Annual Meeting - San Diego, CA
5/29-31/2013 - International Symposium on Focal Therapy & Imaging in Prostate and Kidney Cancer - Amsterdam, the Netherlands
6/21-22/2013 - Resident Graduation Dinner and Alumni Reunion - Durham, NC
7/23/13 - Duke Tuesday in Urology - Duke University Searle Conference Center
11/12/13 - Duke Tuesday in Urology - Duke University Searle Conference Center
4/3-4/6/2014 - 46th Annual Duke Urologic Assembly - Pinehurst, NC