Study found that most subjects developed new demyelinating findings during the active treatment phase of the immune globulin intravenous study even as they were improving clinically. This may reflect ongoing demyelinating activity even as other nerve segments were undergoing repair or remyelination. The appearance of new conduction blocks in patients with CIDP undergoing IVIG therapy has been reported previously. CIDP appears to be a more dynamic disease process than has been appreciated previously, with ongoing demyelination and remyelination, even during periods of apparent clinical remission, similar to what is seen in multiple sclerosis. This might limit the improvement seen in some patients undergoing treatment. Read more!