November 2015 Newsletter

news 
News
Community-Based Research Consult Service
Offered by the Center for Reducing Health Disparities
 
The Center for Reducing Health Disparities offers a free consult service to support and promote the conduct of community-based research by faculty, trainees, and health care providers. Services include, but are not limited to overall project design, survey development, data collection and analysis, grants assistance and funding, focus group creation and implementation, Spanish translation, recruitment, and research translation and dissemination. Click here for additional information. 

To schedule a consult, please contact Katrice Cain at 216-778-8467 or kcain@metrohealth.org. 

Visit www.ReduceDisparity.org to learn more about the Center for Reducing Health Disparities.
Inclusion of Children in Clinical Research: Change in NIH Definition
Issued by the National Institute of Health
 
The purpose of this notice is to notify NIH applicants/offerors and grantees/contractors about a change related to the NIH policy on the inclusion of children in clinical research.  NIH's long-standing policy has been that children must be included in all human subjects' research, conducted or supported by the NIH, unless there are scientific and ethical reasons not to include them.  The policy was developed because medical treatments applied to children are often based upon testing done only in adults, and scientifically evaluated treatments are less available to children due to barriers to their inclusion in research studies.  Therefore, applicants/offerors conducting human subjects' research must include a description of plans for including children.  If children (or a subset of children) will be excluded from the research, the application or proposal must present an acceptable justification.

For more information regarding the definition change, see the NIH Grant webpage.
Community Input Requested: Future Direction of NCATS
Response Deadline: January 8, 2016
 
NCATS seeks input on the scientific and operational opportunities, challenges and 
research needs in translational science, to help set the Center's strategic priorities and inform the development of a five-year strategic plan.

 

Some examples of particular issues of interest that apply across the translational science spectrum include:

  • Breaking down professional, cultural and scientific silos across the translational science spectrum
  • Focusing on inter-operability of data systems (such as integrating patient data and electronic health records into pre-clinical research)
  • Expanding research efforts at NCATS into new therapeutic modalities
  • Focusing on patient-driven research and patient/community engagement
  • Forming innovative partnerships with a wide variety of stakeholders
  • Identifying skillsets and competencies needed for training the next generation of translational scientists
  • Utilizing modern communication and dissemination tools to expand awareness of translational science to a wide variety of stakeholders
For more information, please visit the NIH webpage.
Coming Soon - Nominations for TS2016 Career Achievement and Contributions Awards
 
The sponsoring and partnering organizations of Translational Science 2016 will acknowledge the outstanding contributions of investigators and educators in the field at Translational Science 2016, in Washington, D.C.

Recipients of each award will be recognized during the meeting. Nominations will be accepted for the following awards:
  1. Edward H. Ahrens, Jr Distinguished Investigator Award: This award is named in honor of Edward H. (Pete) Ahrens, Jr., recognizing a senior investigator whose innovative research has had a major impact on clinical practice and health care for the benefit of the public. 
  2. Clinical and Translational Research Distinguished Educator Award: This award recognizes an investigator who has distinguished him or herself as a researcher, mentor and academic leader. Students and trainees are also invited to submit nominations. 
  3. Translational Science Outstanding New Investigator Award: This Award recognizes an investigator's pathway to excellence in achieving an independent research career in biomedical research. The recipient will be required to present his/her research at the AFMR Henry Christian Dinner.
  4. Team Science Award: This award recognizes the importance of interdisciplinary teams to the translation of research discoveries into clinical applications and eventually widespread clinical practice. 
More information about these awards coming soon!

Congratulations to the August 2015 CTSC Core Utilization Pilot Award Recipients

 

John Crabb, PhD at Cleveland Clinic Lerner College of Medicine 
Improved Quantitative Assay for CEP-Ethanolamine         Phospholipids as Plasma Biomarkers for AMD





Ofer Reizes, PhD at Cleveland Clinic Lerner College of Medicine
An Integrated Pathway Approach to Modulate Self-Renewal in Triple Negative Breast Cancer
OHRP Webinar Series on the Common Rule NPRM 

The U.S. Department of Health and Human Services and fifteen other Federal Departments and Agencies have announced proposed revisions to modernize, strengthen, and make more effective the Federal Policy for the Protection of Human Subjects that was promulgated as a Common Rule in 1991. In order to help the public better understand the goals and impact of the new proposals, the Office for Human Research Protections (OHRP) has developed six webinars covering key aspects of the NPRM. The webinars aim to explain the NPRM proposals that are most relevant to each topic.

To watch the webinars, please visit the ACTS Advocacy page.
Consortium for the Advancement of Research Methods and Analysis Webcasts

CARMA, the Consortium for the Advancement of Research Methods and Analysis, is an interdisciplinary consortium devoted to helping faculty, graduate students and professionals learn of current developments in various areas of research methods and statistics. Its focus in research methods is relevant to the management and organizational sciences.

The Office of Research Administration sponsors a membership to CARMA to make the content and materials available to all Case Western Reserve University faculty, staff and students. Live webcasts occur on a monthly basis, and become available in the video archive for viewing at any time.

For more information visit the CARMA webpage.

Questions about CWRU's membership? Email Tracy Wilson-Holden at tjw18@case.edu

PRCHN News  from the PRCHN 
PRCHN Seminars
Mark your calendars for these upcoming PRCHN Seminars.

11/11/15- Community Voices Project: Place and Chronic Disease
Patty Marshall, PhD, Professor of Bioethics, Co-Director, Center for Genetics Research Ethics & Law, CWRU, and Aaron Goldenberg, PhD, MPH, Assistant Professor of Bioethics, Assistant Director of Center for Genetics Research Ethics & Law, CWRU

12/9/15- FreshLink 2.0 Survey Results
Sue Flocke, PhD, Associate Professor, Family Medicine, CWRU and PRCHN Associate Director; Darcy Freedman, PhD, Associate Professor, Epidemiology & Biostatistics and PRCHN Associate Director

You can find more information on these seminars and other PRCHN programs here.

For more news from PRCHN check out their e-newsletter!
The foodNEST Is Recruiting Study Participants
The Future of Food in Your Neighborhood study('foodNEST") is currently recruiting study participants in the St. Clair Superior neighborhood of Cleveland, Ohio and in the Southside neighborhood of Columbus, Ohio.

Potential Cleveland participants should email: foodNESTCLE@case.edu 
or call 216.688.5156 to learn more and see if they are eligible to participate. 

Potential Columbus participants should email: foodNESTCBUS@case.edu
 or 614.641.5359 to learn more or see if they are eligible to participate.

Urbanhealth News from the Urban Health Initiative
Highlights from visits with the Western PA Regional Data Center and FCC Connect2Health Task Force

In collaboration with the Center for Urban Poverty at the Mandel School for the Applied Social Sciences, the Healthdatamatters.org project, led jointly by UHI Director Amy Sheon and MPH Program Director Scott Frank, hosted a visit by Bob Gradeck from the University of Pittsburgh. In several workshop sessions, members of the CWRU and general community learned about how the Western Pennsylvania Regional Data Center is providing public access to community data as a collaboration among the University of Pittsburg, Allegheny County and the City of Pittsburgh. These efforts provide a model for those underway at CWRU. 

On October 26th, the UHI Director briefed the Federal Communications Commission's Connect2Health Task Force during their "Beyond the Beltway" listening session in Cleveland. In such visits, FCC Commissioners seek to understand and promote the "transformative power of broadband technologies and next-generation communications services to improve access to health care services regardless of geography, time, distance or socioeconomic factors." Sheon connected the Commission with several speakers who provided compelling testimony. CWRU faculty member Adam Perzynski spoke about emerging inequalities being seen in use of personal health records associated with disparities in access to broadband services. Sheon advised the Task Force about the inclusion of a Community Health & Wellness focus of last month's Medical Hackathon and presented some of the competitors from that event. Following their nearly 3 hour roundtable, Commissioner Mignon Clyburn gave a keynote address at the Cleveland Clinic's 2015 Medical Innovation Summit, focused on the transformative role of connectivity in health. You can find the roundtable agenda and presentations here. 

Research Research Highlights
CWRU nurse scientist awarded $2.48 million to help families make critical-care decisions 
Award was granted to former CTSC KL2 Scholar Ron Hickman 
A new $2.48 million federal grant will allow researchers at Case Western Reserve University to revise and test the effectiveness of an interactive avatar-based technology that helps users make end-of-life decisions well in advance of an ICU emergency.

 

Each year, millions of Americans are admitted to an intensive care unit (ICU), which can trigger a cascade of difficult decisions about treatment and end-of-life care, especially for patients with chronic illnesses. But more than half of ICU patients haven't documented their end-of-life preferences in any formal way, such as with a living will or medical power of attorney. Click here to read more.
Live Brain Surgery Performed at UH Case Medical Center on Oct. 25th
Performed by neurosurgeon and former KL2 Scholar Jennifer Sweet
 
National Geographic Channel captured the drama of an awake deep brain stimulation (DBS) surgery of a patient with Parkinson's disease. This television event blended live coverage from the operating room at UH Case Medical Center - a first on U.S. television - with pre-produced features that chronicle what science and medicine have historically taught us about the brain, and what is yet to be discovered. The live two-hour special premiered in the U.S. Sunday, Oct. 25, at 9 p.m. on the National Geographic Channel and Nat Geo Mundo, and globally in 171 countries and 45 languages.

Click here for more information about the live two hour special.
Events Events
DataManagementData Management Education Series
All sessions are from 9am-10am in  Lakeside 1400 Conference Room

Don't miss the last three sessions of the eight part Data Management Education Series. 

11/3/15Advanced 2: The Regulations: 21 CFR Part 11
11/10/15Advanced 3: Data Safety Monitoring Board 
11/17/15Advanced 4: Study Infrastructure Template


Have questions about a missed session? Email our research concierge Carolyn Apperson-Hansen at ctsc-research-concierge@case.edu.
Research at CWRU: A boot camp for investigators
November 4, 2015 from 11:30 am- 1:00 pm 
Sears Building room 670

The Office of Research Administration welcomes all new faculty to attend this 90-minute orientation designed to help navigate the university's research grant and regulatory compliance processes and policies. Research Administration staff members will share the university's internal procedures and attendees will receive a binder of helpful information to take away from the presentation. There will be plenty of time for questions.

New faculty are specifically invited, but all faculty are welcome to attend
Done-In-A-Day Research Mob
November 7, 2015 from 10 am- 3:00 pm 
SouthPointe Commons

Recently the Case Center for Reducing Health Disparities heard of the idea of a Research Mob.  The idea was only partially developed, but the concept was intriguing-it seemed that with a little refinement it could be a new way to engage people in research affecting their lives and communities.So we decided to try it out, to learn more about how it could work and test its potential for a range of research questions.

 

The idea is to take a pre-arranged question (below), and in the space of five hours, meet at a central site (MetroHealth), develop a good survey instrument, format it, print it, give copies to teams of people, have them fan out across the community, gather results, return to MetroHealth, tabulate and aggregate results, and distribute those results to an email list of key individuals for reflection and discussion.  In five hours.


For more information see their flyer. 
2015 Neuroendocrine Tumor Regional Conference:
Multidisciplinary Management of NET Cancers
November 7, 2015 at Embassy Suites Cleveland- Independence

The diagnosed incidence of neuroendocrine tumors (NETs) is increasing. In fact, the data shows there has been a 5 fold rise over the last 30 years.  As a result, a vast number of NET patients are seeking care from physicians who may have little knowledge or experience with these diseases. Additionally, the treatment options for patients with neuroendocrine tumors are rapidly being developed. Therefore, there is a clear need to inform community physicians and allied health care providers across the US of the new advances in the field.
 

To address this educational deficit, NANETS has created a regional conference program. The one day event focuses on the standard management of patients with neuroendocrine tumors, sequence of treatments and new therapeutic approaches to these diseases.

Our goal for these conferences is to partner with centers to further develop regional NET teams, increase patient access to clinical trials and improve the ability for NET patients to receive a comprehensive, multidisciplinary management plan. 


For more information and registration, visit the NANETS Regional Conference webpage. 
Seminar in Multidisciplinary Clinical and Translational Research
November 9, 2015 from 12pm-1pm in the WRB room 6136
 
The seminar will address the processes and challenges of multidisciplinary 
clinical/translational science, through which discoveries in the laboratory or in early clinical studies are transformed into interventions, treatments and ultimately, best practices and polices on national and international levels. 

William Schiemann, PhD will discuss Targeting EMT programs and metastasis in breast cancer.

Questions? Please contact Angela Bowling at axb710@case.edu. 
Technology Transfer 101
November 13, 2015 from 12:00-1:00pm in Nord Hall room 356

Join our Technology Transfer staff for an introduction to inventions, working with the Technology Transfer Office and how your research can be translated in to commercial opportunities.
Diversity in Research
November 23, 2015 from 2:30-4:00pm in BRB room 105
 
Diversity in Research explores the scientific, ethical, and legal bases for the inclusion of diverse participants in research and the recruitment and hiring of diverse research staff. Potential barriers to diversity in the research context are discussed.
 
This workshop meets the requirements of the CWRU Office of Inclusion, Diversity, and Equal Opportunity (OIDEO) for participation on CWRU search committees.
The Shared Resource Festival 3.0
December 5, 2015 from 10am-3pm at the City Club of Cleveland

Practice-based research networks (PBRNs) are groups of individuals and agencies that collaborate with academic and community partners to facilitate scientific discovery. For nearly two decades, Ohio healthcare providers and practices have conducted ground-breaking research through participation in practice-based research networks. 

We invite clinicians, academic investigators, practice staff, and volunteers from healthcare, public health, and community settings to join us for this one-day Research Festival focusing on how we can partner to create networks in support of practice-based, population health, and outcomes research.

Join us for an opportunity to share your ideas, disseminate your research findings, get input from others, learn about funding opportunities, develop your ideas, and build collaborations future research endeavors.


 

Funding Funding Opportunities
Robert Wood Johnson Foundation 2016-2017 Health Policy Fellows
Application Deadline: November 12, 2015

The Robert Wood Johnson Foundation Health Policy Fellows program provides the nation's most comprehensive learning experience at the nexus of health, science, and policy in Washington, D.C. It is an outstanding
opportunity for exceptional midcareer health professionals and behavioral and social scientists with an interest in health and health care policy. Fellows participate in the policy process at the federal level and use that leadership experience to improve health, health care, and health policy.

Up to seven awards of up to $165,000 each will be made in 2016. Fellowship funds of up to $104,000 may be used for the residential stay (not to exceed the fellow's salary prior to entering the program) from. The continuation of fringe benefits at levels corresponding to the level of stipend support being requested may be covered with the award, and sponsoring institutions may supplement fellowship funds.

For more information visit the RWJF webpage.

Corporation for National And Community Service - AmeriCorps State and National Grants FY 2016

Letter of Intent Deadline: December 9, 2015

 

AmeriCorps grants are awarded to eligible organizations proposing to engage AmeriCorps member in evidence-based or evidence-informed interventions to strengthen communities. An AmeriCorps member is an individual who engages in community service through an approved national service position. Members may receive a living allowance and other benefits while serving. Upon successful completion of their service, members earn a Segal AmeriCorps Education Award from the National Service Trust that members can use to pay for higher education expenses or apply to qualified student loans. 

 

For more information visit the CNCS webpage.

 
American Psychological Foundation - Alexander Gralnick Research Investigator Prize
Application Deadline: April 15, 2016

The American Psychological Foundation provides financial support for innovative research and programs that enhance the power of psychology to elevate the human condition and advance human potential, both now and for generations to come. To further this goal, the foundation is accepting applications for its 2016 Alexander Gralnick Research Investigator Prize.
The goals of the annual program are to encourage psychologists to assume a leadership role for psychology in the area of serious mental illness; to encourage the training of future psychologists to become leaders in this field; and to provide funding for recipients to ensure that psychologists work to advance understanding and treatment for those who are affected by serious mental illnesses.

In 2015, a single grant of $20,000 will be awarded to an exceptional individual working in the area of serious mental illness, including but not limited to schizophrenia, bipolar disorder, and paranoia (delusional disorder).

For more information visit the APA webpage.

HUB RESOURCE CAPACITY
HubResourceCapacity

Centers of Research Translation (P50)

Application Deadline: December 11, 2015

 

This Funding Opportunity Announcement (FOA) invites applications for Centers of Research Translation (CORT). Overall, a CORT research program could be carried out by a synergistic team of scientists who will address a highly significant translational research challenge in a disease or condition within the mission of the NIAMS. 

 

The focus of research could be either: 

  1. A disease-targeted translational theme addressed by synergistic Research Projects with optional Research Cores or
  2. A disease-related critical translational research question addressed through a single collaborative Research Project enabled by a number of highly interactive Research Cores whose work is integrated over time during the development and implementation of the Project. 

A CORT must have a minimum of three highly meritorious research components consisting of one or more translational Research Projects and one or more Research Cores. An Administrative Core is required in all applications.

 

For more information visit the Grants.gov webpage.

 
Commonwealth Fund Mongan Fellowship in Minority Health Policy
Application Deadline: December 15, 2015

The Commonwealth Fund in Minority Health Policy is now accepting applications for the 2016-17 class. This unique fellowship prepares physicians for leadership roles in transforming health care delivery systems and promoting policies and practices that improve access to high-performance health care for vulnerable populations, including racial and ethnic minorities and economically disadvantaged groups.

Under the auspices of the Minority Faculty Development Program at Harvard Medical School, up to five one-year fellowships will be awarded annually. Fellows will complete academic work leading to a master of public health degree at the Harvard T.H. Chan School of Public Health, or a master of public administration degree at the Harvard Kennedy School for physicians already possessing an M.P.H. Fellows will gain an understanding of major health issues facing vulnerable and disadvantaged populations through seminars, site visits, and other fellowship activities. activities.

For more information visit the CFMF webpage.

InformaticsINFORMATICS
Seeking Innovative Ideas to Advance Open Science
Application Deadline: February 29, 2016

The National Institutes of Health has partnered with London-based Wellcome Trust to launch a global science competition for new products or services to advance "open
 science," a movement to make scientific research data broadly accessible to the public. Up to six teams of technology experts and researchers stand to win $80,000 each to develop their ideas into a prototype or to advance an existing early stage prototype. The prototype judged to have the greatest potential to further open science will receive $230,000.

For more information visit the CTSC webpage.

TrainingAndCareerDevelopmentTRAINING AND CAREER DEVELOPMENT
FDA Fellowship Research Opportunities
Multiple Proposal Deadlines

The ORISE Research Participation Programs at FDA accept applications from students, recent graduates, and faculty researchers year round.

For more information about each opportunity, including instructions concerning the process for submitting an application and other supporting documents, please visit FDA ORISE webpage.  

Henry Luce Foundation/ACLS Program in China Studies Offers Support for Early Career Scholars

Application Deadline: November 4, 2015

 

A program of the Henry Luce Foundation and the American Council of Learned Societies, the Luce Foundation/ACLS Program in China Studies seeks to maintain the vitality of China studies in the United States through fellowships and grants, primarily for scholars early in their careers.

 

The program offers three competitions:

  1. Pre-dissertation Summer Travel Grants for Research in China are designed to enable doctoral candidates to spend three to four months in 2015 gaining familiarity with work under way in archives and field sites in China and to establish formal and informal relations with Chinese institutions and colleagues in preparation for subsequent full-time research in China.
  2. Postdoctoral Fellowships provide support for scholars in preparing their Ph.D. dissertation research for publication or in embarking on new research projects. 
  3. Collaborative Reading-Workshop Grants of up to $15,000 provide opportunities for scholars of different disciplines to share in-depth investigation of texts that are essential points of entry to Chinese periods, traditions, communities, or events in contemporary or historical times. 

For more information visit the ACLS webpage.

 

Rita Allen Foundation: Scholars Program

Letter of Intent Deadline: November 16, 2015

 

The Rita Allen Foundation Scholars Program provides grants to leading medical research institutions selected by the Rita Allen Foundation Scientific Advisory Committee and
 confirmed by the Rita Allen Foundation Board of Directors. The Scholars Program supports research scientists in the early stages of their careers. Fields of research are cancer, immunology, and neuroscience. The Rita Allen Foundation reviews grant proposals by invitation only.

Individuals chosen will be designated Rita Allen Foundation Scholars and the affiliated institution will receive financial support from the Rita Allen Foundation of up to $110,000 annually, for a period of up to five years

.

For more information visit the Office of Research Administration webpage.

 
National Science Foundation Research Traineeship Program
Letter of Intent Deadline: November 20, 2015

The NSF Research Traineeship (NRT) program is designed to encourage the development and implementation of bold, new, and potentially transformative models for STEM graduate education training. The NRT program seeks proposals that ensure that graduate students in research-based master's and doctoral degree programs develop the skills, knowledge, and competencies needed to pursue a range of STEM careers.
 
The NRT program includes two tracks: 
  1. Traineeship Track- dedicated to effective training of STEM graduate students in high priority interdisciplinary research areas, through the use of a comprehensive traineeship model that is innovative, evidence-based, and aligned with changing workforce and research needs.
  2. Innovations in Graduate Education (IGE) Track- focused on test-bed projects aimed at piloting, testing, and validating innovative and potentially transformative approaches to graduate education..
For more information visit the NSF webpage.

TranslationalEndeavorsTRANSLATIONAL ENDEAVORS
BRAIN Public-Private Partnership Program: Industry Partnerships to Facilitate Early Access to Neuromodulation and Recording Devices for Human Clinical Studies 
Pre-Application Deadline: November 18, 2015
Full Application Deadline: April 26, 2016
  • Partnerships between clinical investigators and manufacturers of the latest-generation implantable devices for human clinical research
  • Template Collaborative Research Agreements to streamline agreements between academic institutions and manufacturers
  • Pre-applications (PAR-15-345) for partnering with commercial manufacturers are optional.
  • Full Proposals for Phased Translational-to-Clinical (RFA-NS-16-009) or Direct-to-Clinical (RFA-NS-16-010) Research 
For more information see the slide set and handout summarizing BRAIN Human Research Opportunities.
Lymphatic Education & Research Network Postdoctoral Fellowship Awards Program
Letter of Intent Deadline: January 15, 2016

The Lymphatic Education & Research Network (LE&RN) is committed to supporting basic
and translational research that fosters an interdisciplinary field of investigators conducting lymphatic research. The supported research will improve our understanding and advance the prevention, diagnosis, and novel treatments of lymphedema and other lymphatic disorders. In each grant cycle, at least one fellowship will specifically focus on lymphedema.

Research areas of interest include, but are not limited to:
  • lymphatic vessel biology and pathology
  • physiological mechanisms of normal and pathological lymphangiogenesis
  • animal models of the lymphatic system and its disorders
  • studies that address the regulation of lymphatic structure and function
  • Basic science and translational studies addressing normal and pathological lymphatics in organ systems
  • the signaling between lymphatics and other cell types
For more information visit the HRIA webpage.
Case-Coulter Translational Research Partnership (CCTRP)
Letter of Intent Deadline: February 13, 2016

The Translational Research Partnership (TRP) between Case Western Reserve and the Wallace H. Coulter Foundation fosters collaborations among clinicians and engineers on
 translational research projects with the potential to impact patient care. The program is led by Robert Kirsch, Ph.D, chairman of the Department of Biomedical Engineering and Stephen Fening, PhD, Coulter Program Director.

Funding for full projects can range from $50,000 to $200,000 per year. Smaller pilot grants are available as well. The funding goes towards preparing projects for commercialization, such as demonstrating technical feasibility, market feasibility and industry interest.

For more information visit the CCTRP webpage.

Department of Defense New Funding Opportunities
Have you explored SciVal yet?

Check out SciVal Experts, a directory of researcher expertise that enables collaboration among researchers!
 
Also be sure to contact our Research Concierge Service for all CTSC and research-related queries.

Researchers: Register for an
ORCID ID
NIH has now adopted the ORCID ID, a free, open-source unique identifing number. Learn more about ORCID. It is also recommended that researchers link their ORCID ID to their CV in NIH's SciENcv, which creates a current, customizable biosketch on NIH grant form pages for any NIH grant. If you would like to learn more about how to register and link your ORCID number, please contact: Clara Pelfrey, Evaluation Director at clara.pelfrey@case.edu or (216) 368-6478.

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