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From the Directors
The CTSC is committed to bringing research from lab to life. While we excel in the lab portion of this process, it requires a significant amount of resources and know-how to bring discoveries to life.
A year ago, we set out to expedite and improve the translational process by hiring two Chief Translational Officers, Bill Harte, PhD, and Blair Geho, PhD, MD. Bill and Blair, who have pharma and biotechnology experience, are here to assess and advise research projects, educate junior faculty, fellows and graduate students in technology transfer and development of research ideas, and move promising product concepts quickly from discovery to development. These are things that our CTO's are adept at doing, having brought biomedical discoveries to market themselves prior to their hire.
Bill and Blair seek to identify and determine which discoveries can have potential for translation and possible commercialization and help expedite the process working closely with faculty. Among other things, this requires an industrial/business point of view and the ability to navigate the investment and development landscape. More importantly, this requires the savvy to expose discoveries to those in the commercial realm who will look at them from a different lens. The early stages of the process involve producing a set, of what we like to call; "Killer Experiments" which help determine a discovery's commercial potential. After this phase, the CTOs are there to guide a project on to further development. Even if a project does not pass the "Killer Experiment" phase focused on commercialization, discoveries can still produce great scientific value. The CTOs can help greatly with this determination.
As investigators ourselves, we know there can be great apprehension for a researcher regarding the commercialization process. Because it can be unfamiliar territory, there are often concerns about taking time away from the lab, potential funding opportunities and publications. The Chief Translational Officers are here to help. The CTOs can assist in all issues related to tech transfer and the patent process, and help investigators understand commercialization from start to finish. Often times, this guidance can lead to additional funding and help improve an investigator's academic career. The CTOs are available if you have any questions at all regarding this process and how it relates to and can improve your research. They are working with every CTSC partner institution and have several projects in the works. For example, a project originating at the Cleveland Clinic is under consideration for joint funding by both the Cleveland Clinic Innovations and the School of Medicine under the School of Medicine's Council for the Advancement of Human Health (CAHH). This project originated by a scientist at the Clinic who is also a CWRU professor and would involve the active participation by the School of Medicine's CTOs to determine the commercial feasibility of the project. Other projects have involved scientists at University Hospitals/Case Medical Center and Metro Health as well as the Case Western Reserve University School of Medicine. Investigators at institutions other than the CWRU School of Medicine can contact the CWRU CTOs via their own tech transfer officers.
We have a great amount of confidence that the CTO implementation will drastically shorten the discovery/commercialization timeline. Bill and Blair are willing to speak with any investigators no matter where they are in the research process.
Feel free to get started by contacting them today:
Bill Harte, PhD Blair Geho, MD, PhD
wxh179@case.edu bxg157@case.edu
805-701-0774 330-466-4100
http://casemed.case.edu/ora/chieftranslationalofficers.cfm
Pamela B. Davis, M.D., PhD Richard Rudick, M.D.
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Research Concierge Can Help You With Your Research
The RCS offers the researcher a single point of contact to 1) assist them, quickly and efficiently, at the initial project design stage and strategize the path forward; 2) shorten the amount of time researchers spend searching for valuable information; and 3) match researchers with the CTSC cores where core personnel can identify specific research needs and connect the researcher with the person whose specialized expertise can best support the project. The RCS also helps identify non-CTSC resources as well as provide education about the CTSC, the research process, and proposal development.
The services of the RCS currently provided, both in-person and virtually, are:
- Answer questions about CTSC services
- Match research needs to core services
- Navigate inexperienced researchers on the nuts and bolts of getting a study underway (e.g., discussing formats and sections for protocols, data tools, managing data, locating needed data resources)
- Assist data flow design and identification of data tools for studies (not database development but help to find the appropriate database and support for this activity)
- Administer CTSC Pilot Funding Program
- Provide guidance on regulatory requirements as well as data safety and monitoring
- Provide education on the overall research process
- Link researchers across disciplines and institutions
Reaching out for new ideas and collaborations! How can we help you?
CTSC Research Concierge Service:
BRB RM 109
ctsc-research-concierge@case.edu
216-368-0035
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Many CTSC Services Available
The CTSC has a myriad of services available no matter the stage of your scientific career. In most instances, CTSC resources are just a phone call or email away. The CTSC staff is knowledgeable in many areas of research and can respond quickly.
Provides and manage shared IT and informatics resources that make effective implementation of the entire program possible. These include a wide array of services, such as computerized tools, systems, underlying connectivity, and computer security required to support the multi-faceted clinical and translational research undertaking.
See the BRIM core for big data management guidance and consultation and informatics support.
The CTSC BERD comprises experts in epidemiology and biostatistics across the CTSC partner institutions. They provide a shared infrastructure of epidemiological and biostatistical resources to support CTSC researchers in three key areas:
- Development of optimal study designs and statistical analysis plans for study protocols: BERD experts provide free support for the development of research protocols submitted to funding agencies.
- Development of novel study designs and statistical methods that can be applied to translational research.
- Educating and mentoring early stage investigators (basic scientists, clinicians, epidemiologists, and biostatisticians) in study design and statistical analysis
Regulatory Knowledge Support:
The main goal of the Regulatory Knowledge Support Core is to build integrity into clinical and translational research programs, promote responsible conduct, and help investigators meet their regulatory responsibilities by establishing a CTSC program in which ethical values serve as the driver of regulatory knowledge and support.
Investigators can utilize the Regulatory Core for help with many applications including: Institutional Review Board (IRB), Investigational New Drug (IND) compliance, Investigational Device Exemption (IDE) guidance, as well as other regulatory burdens.
For access to these and many other CTSC services, contact:
CTSC Research Concierge Service:
BRB RM 109
ctsc-research-concierge@case.edu
216-368-0035
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NY Times Article Calls Attention to Research Participant Privacy
A recent article in the New York Times highlighted the difficulties and risks associated with research participant data and participant privacy.
Read the full article here
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CTSC Dashboard Coming Soon!
The CTSC Dashboard will launch February 4th. The Dashboard will be open to anyone to view the activities of the CTSC primary cores. This will be useful information in the tracking and planning of CTSC activities. Look for an update and link coming soon!
For more information:
CTSC Research Concierge Service
ctsc-research-concierge@case.edu
Phone: 216-368-0035
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CTSA Tool Shop Webinar:
Harvard Catalyst Profiles Research Networking Software
When:
Friday, February 15, 2013
Overview:
Profiles Research Networking Software is an NIH-funded open source tool to speed the process of finding researchers with specific areas of expertise for collaboration and professional networking. Profiles RNS imports and analyzes "white pages" information, publications, and other data sources to create and maintain a complete searchable library of web-based electronic CVs. Built-in network analysis and data visualization tools allow administrators to generate research portfolios of their institution, discover connections between parts of their organization, and understand what factors influence collaboration.
Register Now
For more information on CTSA Tool Shop Webinars click here |
University of Cincinnati Presents:
Empirical Bioethics- Emerging Trends for the 21st Century
Empirical bioethics involves the measurement and evaluation of ethical principles. During this 2-day conference, participants will learn about cutting-edge research that defines the ethical framework guiding clinical and translational studies. Speakers include internationally recognized experts in the application of bioethics to clinical research and medicine.
Keynote Presenter (Feb. 21):
Daniel Sulmasy, MD, PhD, professor of medicine and associate director of the MacLean Center for Medical Ethics, University of Chicago.
Ethics and Evidence: What Data Can and Cannot Do for Bioethics.
When:
Thurs., February 21 (1:00-6:15 PM) Fri., February 22 (8:15 AM-4:20 PM)
Where:
Kingsgate Marriott Conference Center, 151 Goodman Dr., University of Cincinnati. A limited number of guest rooms are available at the UC business rate of $145+tax. Mention the code UVCR when registering by phone at
1-800-228-9290.
Who may attend:
Open to the public. Continuing medical education (CME) and Ohio Psychological Association (OPA) continuing education Ethics credit offered.
Cost:
$100. Includes all conference materials, reception for attendees (Thursday), continental breakfast and lunch (Friday), and breaks.
Click Here for more information and registration. Registration required by February 15, 2013
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Cultural Competency Book Discussion: "The Immortal Life of Henrietta Lacks"
by Rebecca Skloot
When:
5:30pm-7:00pm
Where:
MetroHealth Medical Center,
Rammelkamp Atrium, R170
2500 MetroHealth Drive
Cleveland, Ohio 44109
The Case Center for Reducing Health Disparities presents a Cultural Competency Book Discussion on "The Immortal Life of Henrietta Lacks".
The purpose of this book discussion is to discuss cultural issues/themes found within the book and how they relate to conducting and participating in medical research.
Principle Investigators, Study Coordinators, and community members are invited to attend. Researchers will be awarded Continuing Research Education Credits
Please RSVP by March 1, 2013:
Katrice Cain
Program Development Manager
216-778-8467 kcain@metrohealth.org
More
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Slides and Videos from:
"So You Want To Do
Comparative Effectiveness
Research?"
On December 14, 2012, the CTSC hosted a symposium on Comparative Effectiveness Research entitled: "So You Want To Do Comparative Effectiveness Research?"
The Symposium featured speakers David Kaelber, MD, PhD, MPH, Anil Jain, MD, FACP, Siran Koroukian, PhD, Mendel Singer, PhD, MPH and Shari Bolen, MD, MPH
For those who may have missed it, video and slide presentations of the symposium can be found on the CTSC website here.
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