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FDA approves new treatment for rare form of hemophilia


2015 PBMI Conference
SUMMARY OF TOP ARTICLES - OCTOBER 30, 2014

Sovaldi Compliance Rates Show Room for Improved Management
Specialty Pharmacy News - October 28, 2014
After Gilead Sciences, Inc.’s hepatitis C therapy Sovaldi (sofosbuvir) launched in December, much of the attention on the drug has focused on its $1,000-per-day price. But in clinical trials, the drug had sustained virologic response rates of more than 90%, making it much more effective than any previous therapy. However, a drug can be effective only if someone adheres to the proper treatment regimen, and early results are showing a mix of compliance rates among patient populations.

Powerful new class of weapons found in the war on cancer
ScienceDaily - October 23, 2014
Small molecules that can represent a new class of anticancer drugs with a novel target for the treatment of lung cancer have been identified by an interdisciplinary team of researchers. "These compounds hold potential as an entirely new class of anticancer drugs with a unique therapeutic target for the treatment of cancers," one expert noted.

Hospitals Furious at Cancer-Drug Price Hikes
Time - October 27, 2014
Some of the nation’s hospitals are seriously ticked off at Genentech, the San Francisco biotech firm, for implementing a stealth price hike for three critical cancer drugs.

Heart Drug May Help Treat ALS, Mouse Study Shows
Washington University of St. Louis - October 27, 2014
Digoxin, a medication used in the treatment of heart failure, may be adaptable for the treatment of amyotrophic lateral sclerosis (ALS), a progressive, paralyzing disease, suggests new research at Washington University School of Medicine in St. Louis.

Do the feds expect to lose the subsidy battle?
Healthcare Dive - October 28, 2014
New language in the contracts between exchange insurers and the Centers for Medicare and Medicaid Services will permit insurers to stop offering plans if federal subsidies should no longer be available.

Nanoparticle-based invention moves new drugs closer to clinical testing
ScienceDaily - October 22, 2014
A nanoparticle has been developed to deliver a melanoma-fighting drug directly to the cancer. Delivering cancer drugs directly to tumors is difficult. Scientists are working on new approaches to overcome the natural limitations of drugs, including loading them into nanoparticles.

FDA approves cancer drugs without proof they're extending lives
Journal Sentinel - October 26, 2014
Other measures are used to determine whether new medicines should reach patients.

Painkiller deaths drop for first time since 1999
USA TODAY - October 15, 2014
New federal data show deaths from prescription painkillers have decreased for the first time since 1999, while heroin deaths have surged, suggesting some addicts may have turned to illicit drugs as new federal and state restrictions made prescription narcotics harder to get.

Randomized Trial of Telephone Outreach to Improve Medication Adherence and Metabolic Control in Adults With Diabetes
American Diabetes Association - September 15, 2014
Medication nonadherence is a major obstacle to better control of glucose, blood pressure (BP), and LDL cholesterol in adults with diabetes. Inexpensive effective strategies to increase medication adherence are needed.

HHS Secretary announces $840 million initiative to improve patient care and lower costs
U.S. Department of Health & Human Services - October 23, 2014
New initiative will support networks that help doctors access information and improve health outcomes.


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