The Center on Trauma and Children (CTAC) is dedicated to the enhancement of the health and well-being of children and their families through research, service and dissemination of information about child abuse and trauma. Visit our website: www.uky.edu/CTAC
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Research to Practice- Special Edition
This edition of Evidence in Action is an annual feature in which CTAC scientist-practitioners share clinical implications of a specific research study to illustrate how the findings can be used in trauma practice. For this issue, CTAC Faculty Associate Debra Katz, M.D. discusses a 2013 paper published in the American Journal of Psychiatry on childhood trauma and psychosis. The reference for this paper is as follows:
Kelleher I, Keeley H, Corcoran P, Ramsay H, Wasserman C, Carli V, Sarchiapone M, Hoven C, Wasserman D, Cannon M: Childhood trauma and psychosis in a prospective cohort study: cause, effect, and directionality. Am J Psychiatry 2013; 170:734-741.
Psychosis and Trauma
A growing number of studies are examining childhood trauma as a risk factor for the development of psychosis (Varese et al., 2012; Read et al., 2001; Shevlin et al., 2007). Many questions remain, however, about whether experiences of physical or sexual abuse, neglect, bullying, and parental loss and separation are merely associated with psychotic symptoms or are causal.
A recent study published in the American Journal of Psychiatry (Kelleher et al., 2013) attempts to answer the following important questions:
(1) Does childhood trauma increase the likelihood of psychotic symptoms or experiences?
(2) Does the elimination of trauma exposure bring about a cessation/ reduction of psychotic experiences?
(3) What is the direction of the relationship between childhood trauma and psychotic experiences? For example, most research has focused on childhood traumatic experiences increasing the risk for psychotic symptoms, but could the direction be reversed? Could psychotic experiences increase the risk for exposure to trauma?
The answers to these questions have profound clinical implications in assessing, monitoring and treating traumatized children. For example, if psychotic symptoms are clearly linked with traumatic experiences in childhood and resolve after the traumatic exposure ends, clinicians might be able to more comfortably assess and follow these symptoms with a trauma-focused treatment approach. On the other hand, if psychotic symptoms are independent of traumatic exposure and persist or intensify despite cessation of traumatic exposure or treatment, the clinical management and prognosis would be different, and the child may need to be referred for specific evaluation and treatment of the psychotic symptoms.
The Study
As part of a collaborative, multinational European project, researchers in Ireland conducted a longitudinal, prospective study of 1,112 school-based adolescents, 13-16 years of age. Students completed self-report measures at baseline, and at 3 months and 12 months. Childhood trauma was defined as physical assault or bullying and psychotic experiences were identified by the presence of auditory hallucinations. The findings revealed a bidirectional relationship between childhood trauma and psychosis, meaning that trauma was shown to predict psychotic experiences over time and psychotic experiences were shown to predict trauma. Even after accounting for this bidirectional relationship with a number of statistical adjustments, trauma was strongly predictive of psychotic experiences. A dose-response relationship was observed between the severity of bullying and the risk for psychotic experiences. Importantly, the cessation of trauma experiences predicted the cessation of psychotic symptoms. The incidence of psychotic experiences decreased significantly in adolescents whose exposure to trauma ended over the course of the study.
The authors concluded that exposure to childhood trauma predicted new incidences of psychotic experiences. This study provides the first direct evidence that the termination of traumatic experiences leads to a reduced incidence of psychotic experiences.
Implications for Practice
Psychotic symptoms in adolescents or young adults may be particularly worrisome to clinicians since serious illnesses like schizophrenia or bipolar disorder often present in adolescence or young adulthood. Trauma is often not considered when a child or adolescent endorses psychotic symptoms, which often leads to referral for psychiatric evaluation to diagnose or treat these symptoms. This article demonstrates not just a strong association between trauma exposure and the development of psychotic symptoms but confirms trauma as a causal factor for psychotic experiences. This was demonstrated by the strong temporal relationship between exposure to childhood trauma and the onset of psychotic experiences, the dose-response relationship between the two and the fact that the cessation of childhood trauma led to a cessation of psychotic experiences. |
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PRACTICE CONSIDERATIONS
- Trauma exposure should be carefully investigated in every child presenting with psychotic symptoms.
- Understanding that psychotic symptoms abate when trauma exposure ends adds a sense of urgency in ensuring that children are in safe environments. This is the highest priority in trauma treatment but may not be as strongly considered when treating a child with psychotic experiences.
- Bullying constitutes a significant trauma exposure and is strongly linked in this study with psychotic symptoms. Inquiring about bullying is an important part of a trauma assessment in children and adolescents.
- Psychosis and trauma have a bidirectional relationship. Children with psychotic symptoms are at increased risk for traumatic experiences and children who are traumatized have an increased risk of psychotic symptoms.
- Both biological and psychological factors play a role in both psychotic experiences and trauma.
- A dose response relationship exists between the number of traumatic experiences an individual has had and the later development of psychosis (Shevlin et al., 2008). This is especially relevant clinically in monitoring children and adolescents who have had multiple or ongoing traumatic experiences.
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Final Thoughts on the Study
This study investigated only physical abuse and bullying therefore other forms of trauma were not assessed. In addition, an index question for psychotic symptoms about auditory hallucinations may have left out other relevant psychotic experiences like delusions or paranoia. Nevertheless, a major finding of this study is that changes in the environment-namely, a cessation of trauma exposure---predicts a cessation of psychotic experiences. This is particularly relevant for psychiatrists and other physicians who may rush to prescribe medication or to hospitalize children who endorse psychotic symptoms. This study highlights the importance of thinking carefully and broadly about the kinds of experiences associated with psychotic symptoms and working actively to modify them. While many forms of traumatic exposure were not assessed in this study, physical abuse and bullying were clearly linked with psychotic symptoms, lending support to a careful trauma assessment, including assessment of peer victimization or bullying, in all children. The findings from this study call for the development of specific interventions to reduce traumatic exposure for individual children and for comprehensive prevention, education and intervention programs for professionals working with children and adolescents. This study provides evidence that reducing traumatic exposure in a variety of settings will lead to a reduction of psychotic experiences in children and adolescents, and may prevent mislabeling and inappropriate treatment of children with psychotic symptoms.
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References
Kelleher, I., Keeley, H., Corcoran, P., Ramsay, H., Wasserman, C.,
Carli, V., Sarchiapone, M., Hoven, C., Wasserman, D., Cannon, M.
(2013). Childhood trauma and psychosis in a prospective cohort
study: Cause, effect, and directionality. American Journal of
Psychiatry, 170, 734-741.
Read, J., Perry, B.D., Moskowitz, A., Connolly, J. (2001). The
contribution of early traumatic events to schizophrenia in some
patients: A traumagenic neurodevelopmental model.
Psychiatry, 64, 319-345.
Shevlin, M., Dorahy, M.J., Adamson, G. (2007). Trauma and
psychosis: An analysis of the National Comorbidity Survey.
American Journal of Psychiatry, 164, 166-169.
Shevlin, M., Houston, J., Dorahy, M., Adamson, G. (2008). Cumulative
traumas and psychosis: An analysis of the National Comorbidity
Survey and the British Psychiatric Morbidity Survey.
Schizophrenia Bulletin, 34, 193-199.
Varese, F., Smeets, F., Drukker, M., Lieverse, R., Lataster, T.,
Viechtbauer, W., Read, J., van Os, J., Bentall, R.P. (2012).
Childhood adversities increase the risk of psychosis: A
meta-analysis of patient- control, prospective, and cross-
sectional cohort studies. Schizophrenia Bulletin, 38, 661-671. |
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