In her talk today, Dr. Davis will discuss how pain perception varies from person to person and  how an individual's experience of pain can vary depending on their attentional state and other cognitive and emotional factors that can be state-dependent and thus fluctuate on a moment-by-moment basis. Her talk will review the evidence for brain features that underlie individual differences in pain and attentional effects. She will present a new concept of a "pain switch" developed to account for the nuances of individual pain experiences, the core feeling of "ouch" that is known to us all and is fundamental to pain (Davis et al, Pain 2015) that does not require intensity-coding. Understanding the dynamic pain connectome and pain switch is critical to develop further theories of pain and the practical application of developing an imaging-based objective measure of pain (i.e., a "painometer").