National Cancer Institute
Epidemiology and Genomics Research
August 2013

About Us 

Funding Opportunity

Sage Bionetworks/DREAM Challenges 

Breast Cancer Network Inference Challenge, Toxicogenetics Challenge, and Whole-Cell Parameter Estimation Challenge 

Submissions due by September 15, 2013 


Health Disparity Research Award and Population Science Impact Award
Pre-application submissions due by September 18, 2013
Collaborative Research Infrastructure to Develop Research Strategies to Identify Potential Therapeutic Targets Based on Genetic Factors Influencing Human Life Span and Health Span (U24)
Application due date: November 4, 2013
Expires November 5, 2013

Centers of Excellence for Big Data Computing in the Biomedical Sciences (U54)
Application due date: November 20, 2013
Expires November 21, 2013


NLM Administrative Supplements for Informationist Services in NIH-Funded Research Projects

Application due date: November 5, 2013

Expires November 6, 2013   


Research on the Role of Epigenetics in Social, Behavioral, Environmental, and Biological Relationships throughout the Life-Span and Across Generations (R21)
Application due date: November 13, 2013
Expires November 14, 2013


Bridging the Gap Between Cancer Mechanism and Population Science (U01)

Application due dates: November 4, 2013; June 17, 2014; November 4, 2014; June 17, 2015; November 4, 2015  

Expires November 5, 2015   



Research Project Grant (Parent R01)

Application due dates: Standard dates apply 

Expires September 8, 2016 


Request for InformationRequestforInfo


Request for Information (RFI): Input on Development of Analysis Methods and Software for Big Data  

Response Date: September 6, 2013 


Grants Policy AnnouncementGrantsmanshipAnnouncements


NIH to Require Use of Updated Electronic Application Forms
With some exceptions, all applicants will be required to use electronic application forms packages for due dates on or after September 25, 2013.   



Now Available: PHS 398 Application Forms and Instructions for Application Due Dates on or after September 25, 2013 and Updated Application Guides for Electronic Application Forms 

Job OpportunitiesJobOpportunity
Program Director, Cancer Epidemiology Cohort and Consortia Coordination

Program Director, Clinical and Translational Epidemiology Branch

Cancer Research Training Award Fellow, Cancer Epidemiology Cohort and Consortia Coordination

Upcoming Seminars & WorkshopsEvents
Webinar:  New Developments in the Tobacco Use Supplement to the Current Population Survey

September 17, 2013, 1:30-3:30 ET 


October, 16-17 2013 in Cambridge, UK
October 28-30, 2013 in Sioux Falls, SD

2013 Cohort Consortium Annual Meeting

November 18-19, 2013 in Rockville, MD

Blog PostBlogPost
The Epidemiology and Genomics Research Program (EGRP), in the Division of Cancer Control and Population Sciences (DCCPS) funds research in human populations to understand the causes of cancer and related outcomes.

The Program fosters interdisciplinary collaborations, as well as the development and use of resources and technologies to advance cancer research and translation of this research, which serve as the basis for clinical and public health interventions.
Send Us Your IdeasSendUsYourIdeas
EGRP encourages readers to submit items of interest to Cancer Epidemiology Matters E-News EGRP reserves the right to decide whether or not materials are appropriate for inclusion.
Contact UsContactUs
Epidemiology and Genomics Research Program
Division of Cancer Control and Population Sciences
National Cancer Institute
9609 Medical Center Drive
4 East, MSC 9763
Bethesda, MD  20892
(240) 276-6730

For UPS, FedEx, and courier services, please use:
Rockville, MD  20850


New Cancer Data Access System (CDAS) Includes Data from NLST and PLCO TrialsCancerData
NCI recently launched a new resource to provide investigators with access to data from the National Lung Screening Trial  (NLST) and the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial. The Cancer Data Access System (CDAS) website allows interested investigators to request access to data from PLCO and NLST. All requests are reviewed by NCI trial leadership; upon approval, investigators are granted access to the requested data for a limited amount of time. 


CDAS provides extensive documentation for each trial, including a summary of the trial, a description of the data collected, and a searchable list of research projects and publications. Analytic data sets for prostate, lung, colorectal, ovarian and 14 other common sites of interest are available through a standard request. These data sets contain nearly all the study data available for screening, incidence and mortality analyses. Special requests can be made for multiple cancers, other cancers, questionnaire data, or sensitive data.    

All future requests for PLCO data that do not include biospecimens will be handled through the CDAS. Any requests involving biospecimens will continue to be reviewed and tracked through the PLCO website. Existing projects that have an approved Proposal Application Form (PAF) will not need to re-apply though the CDAS system. 

Prior Approval Needed to Modify Aims and Approaches in NCI-Funded StudiesNCI_FundedStudies

It is sometimes necessary for a Principal Investigator (PI) to make modifications to the methodology, approach or other aspects of study objectives from an initial peer-reviewed application. Although a PI for an NCI-funded study is permitted to make modifications limited in scope from the initial funded application without prior program approval, it is strongly recommended that the PI contact their NCI Program Director (PD) if such a modification is anticipated. However, EGRP now requires that PIs request prior approval from NCI if those modifications result in a change of scope, specific aims, objectives, purpose, or type of research. The PI must make the initial determination of the significance of a change and must consult with the PD or Grants Management Specialist as necessary.

Potential indicators of a change in scope include, but are not limited to:  
  • Change in the specific aims approved at the time of award.
  • Substitution of one animal model for another.
  • Change from the approved use of live vertebrate animals or involvement of human subjects.  
  • Shift of the research emphasis from one disease area to another.
  • Application of a new technology, e.g., changing assays from those approved to a different type of assay.
  • Transfer of the performance of substantive programmatic work to a third party through a consortium agreement, by contract, or any other means.
  • Significant rebudgeting, when expenditures in a single budget category deviate from the commitment level established for the budget period by 25 percent or more of the total costs awarded for that year.     
  • Addition of a foreign site.
The PI is not permitted to proceed with these changes without prior approval of an NIH Grants Management Specialist and PD. To request a modification of the methodology, approach, and/or specific aims, the PI should submit a request through their Office of Sponsored Research to the NCI Grants Management Specialist and the PD. The request should not be part of the annual non-competing (type-5) progress report; instead, a separate request prior to submission of the annual progress report is preferred. This will allow adequate time for review, and for the PI to address any concerns without causing delays in the next non-competing award. The request should describe the modification(s) in detail, noting any resultant changes to the study objectives or budget.  


The Grants Management Specialist will review the request to make sure the proposed modifications are in compliance with NIH and NCI funding policies. The PD will review the request to determine if:

  • The overall study objective will still be met;
  • The budget is appropriate for the proposed modifications;
  • There is sufficient time remaining on the study to complete the original and modified aims. 
If the PI anticipates that a foreign site will be added to the study, it is important to inform your PD as soon as possible, as the addition of a foreign component requires that the PD submit a foreign clearance request . Clearance must be received before the request can be fully processed by the NCI's Office of Grants Administration.  

If questions or concerns are raised during the review, the PD will request additional information and may request a teleconference to discuss the request. PIs should direct any questions about this policy to their PD or the Grants Management Specialist noted on their last Notice of Grant Award.

OGA will inform the PI of NCI's decision about the request, and when the foreign clearance request has been approved and processed. At that time the PI may proceed with the modifications.

Learn more about activities and/or expenditures that require NIH prior approval. 
Grant Award Renewal Funding Contingent Upon Public Access to NIH-Funded PublicationsGrantRenewalFunding
Since 2008, the NIH Public Access Policy has required investigators funded by the NIH to submit an electronic version of all final, peer-reviewed manuscripts to the National Library of Medicine's PubMed Central. Compliance with the Public Access Policy has been a statutory requirement and a term and condition of all grant awards and cooperative agreements.


The NIH Guide for Grants and Contracts' Notices NOT-OD-12-160 and NOT-OD-13-042 state that non-competing continuation grant awards with a start date on or after July 1, 2013 will not be processed until a principal investigator (PI) submits a PubMed Central reference number (PMCID) or
a NIH Manuscript Submission Reference Number (NIHMSID)  for every paper cited that arose from that award. Listing one of these publications anywhere in a  Research Performance Progress Report (RPPR) or a paper progress report (PHS 2590) without the appropriate identifier is not consistent with the requirements of the public access policy and will delay the processing of the award.


Investigators will need to use My NCBI to enter papers onto progress reports. NIH has made changes to My NCBI that make it easier for PD/PIs to track compliance of all papers arising from their awards, even if they do not author those papers. Papers can be associated electronically using the RPPR or included in the PHS 2590 using the My NCBI-generated PDF report.


Learn more about using My NCBI for public access compliance tracking.


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Epidemiology and Genomics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute | 9609 Medical Center Drive | 4 East, MSC 9763 | Bethesda | MD 20892

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