June 2014
Table of Contents
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Shared Resource Spotlight
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Tissue and Data Acquisition and Analysis Core
The Tissue and Data Acquisition and Analysis Core (TDAAC) is a resource designed to provide high-quality controlled human tissue samples to investigators as well as provide customized services to assist them in all tissue collection, consenting and processing needs.
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Leaders' Update 
A message from Khalid Matin, M.D., F.A.C.P.,
medical director of community oncology and clinical research affiliations
I am pleased to provide an update on clinical research affiliations at Massey, which continue to expand in several ways.
This message continues with information regarding:
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Research Highlights
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Developmental Therapeutics
member
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Landmark research establishes a new standard of care for young women with hormone-sensitive breast cancer
An international study is the first to demonstrate that exemestane is more effective than tamoxifen at preventing recurrence in young women with hormone-sensitive breast cancer.
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Developmental Therapeutics
member
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Whole exome sequencing shows potential to improve efficacy of stem cell transplantation
Researchers have sequenced the DNA of a small group of stem cell transplant recipients and their donors and discovered significant variation in their exomes that may help explain why some human leucocyte antigen-matched stem cell transplant recipients still suffer from graft-versus-host-disease.
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Center News
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 Visiting scholar researches palliative and end-of-life care at VCU Jane Seymour, Ph.D., professor of palliative and end-of-life studies in the School of Nursing, Midwifery and Physiotherapy at the University of Nottingham, traveled to VCU from the United Kingdom in April to begin her summer-long appointment as a VCU Global Visiting Scholar.
Seymour will spend her summer consulting with Massey's clinical team and others in and outside of VCU Medical Center, participating in the interdisciplinary rounds of Massey's palliative care team and giving formal talks and presentations.
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Member Showcase
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non-aligned member
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As chief research information officer, Fenstermacher leads VCU's clinical and translational informatics program
David A. Fenstermacher, Ph.D., VCU chief research information officer and a Massey research member, has a strong background in research informatics, health information systems and clinical research.
His current research focuses on developing informatics resources specifically for comparative effectiveness research and precision medicine.
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Researcher Recognition
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Reed receives $2 million grant to improve melanoma treatment
Jason Reed, Ph.D., has been awarded a roughly $2 million grant with a collaborator at the University of California, Los Angeles, to develop a new method to rapidly determine how a cancerous tumor responds to a battery of candidate therapies and then to pick the agents that are most effective for treating the patient's particular disease.
Reed has proposed to develop a new, rapid, high-throughput, real-time, generic drug response quantifier, called Live Cell Interferometry (LCI), on an open platform configuration to handle issues of tissue and growth heterogeneity that typically accompany all tumor types.
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