November/December 2013
Table of Contents
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Shared Resource Spotlight
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Cancer Research Informatics and Services Core
The mission of the CRIS core is to provide novel informatics services that support and enhance research activities across Massey.
A highlight of the CRIS core is the Clinical Trials Eligibility Database Automatching tool, which screens patient data from a combination of sources and evaluates these data against eligibility criteria for each study.
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Leaders' Update 
A message from Laura Siminoff, Ph.D., associate director for cancer prevention and control
Cancer prevention and control (CPC) research at Massey stretches across the entire cancer continuum.
This message continues with information about:
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Research Highlights
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Waterpipe tobacco smoking found to be as harmful as cigarette smoking
Researchers worldwide met at the first ever International Conference on Waterpipe Tobacco Research to review the evidence that waterpipe tobacco smoking is as harmful as cigarette smoking and recommend actions to curb the waterpipe tobacco pandemic.
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Newly discovered gene interaction could lead to novel cancer therapies
Forced expression of MDA-7/IL-24 (melanoma differentiation associated gene-7/interlukin-24) was found to stimulate SARI (suppressor of AP-1, induced by interferon) expression in what is known as an autocrine/paracrine loop, which ultimately causes cancer cells to undergo apoptosis.
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Center News
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New Massey video provides perspective
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A new video developed by Massey introduces the idea of "perspective" through the stories of three patients.
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Massey hosts Holiday Traditions Potluck
Join Massey for a holiday potluck on Monday, December 16 at 11:30 a.m. to 2 p.m. RSVP to Courtney Culbreth at x63051 or cculbreth@vcu.edu.
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Member Showcase
Matin named medical director of community oncology and clinical
research affiliations
Massey welcomes Khalid Matin, M.D., F.A.C.P., as a new member of the Developmental Therapeutics program and medical director of community oncology and clinical research affiliations.
A board certified medical oncologist and clinical researcher, Matin is an expert in the study and treatment of gastrointestinal cancers. He has developed several clinical trials for GI cancers, and he has served as the principal investigator and co-investigator on various colorectal and lung cancer trials.
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Researcher Recognition
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Massey pilot awards and multi-investigator funding
Congratulations to the following Massey pilot grant award winners:
- Keith Ellis, Ph.D., Steven Grossman, M.D., Ph.D., and Glen Kellogg, Ph.D., for
- Youngman Oh, Ph.D., and Steven Grossman, M.D., Ph.D., for "Development of novel therapies for chronic colitis-associated colorectal cancer"
- Nicholas Farrell, Ph.D., and Lawrence Povirk, Ph.D., for
Also, congratulations to the following Massey multi-investigator award winners:
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- Andrew Larner, M.D., Ph.D., and Kazuaki Takabe, M.D., Ph.D., for "Role of mitochondrial Stat3 in breast cancer growth and progression"
- Shirley Taylor, Ph.D., and John Hackett, Ph.D., for "Structural and biochemical consequences of mitochondrial DNA methylation on function of mTERF"
- Hu Yang, Ph.D., and Kristoffer Valerie, Ph.D., for "Synthetically lethal Topol-ATM inhibitor nanoparticles for glioma therapy"
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