Biomedical Research. Scientific departments are focused on finding answers to some of the most critical biomedical questions and, ultimately, to understanding in detail the fundamental processes of life. The overarching goal of this research focus is the development of therapeutic opportunities in several important disease areas.  Scripps Florida's research targets include, among others, neurobiology (Alzheimer's, Parkinson's, autism, schizophrenia, anxiety/depression and addiction), cancer biology, immune system studies (asthma, rheumatoid arthritis), cardiovascular and metabolic research (heart disease, diabetes, obesity and metabolic syndrome), and infectious diseases (Creutzfeldt-Jakob disease, malaria, tuberculosis, hepatitis C, HIV/AIDS).

Advanced Technologies. Scripps Florida has made a major commitment to the development, acquisition, and expanded use of advanced technologies for the post-genome era of modern biomedical research.  The Translational Research Institute combines basic research with advanced technology platforms or "cores" to develop potential lead compounds that can prevent, treat, or cure disease.

The Genomics Core generates data and manages its collection and initial processing related to micro-array analysis and new generation deep sequencing. Micro-arrays, also known as gene chips, are basically glass or silicon wafers with short fragments of RNA and/or DNA deposited on their surface. By placing cell or tissue samples on these wafers, scientists can study which genes are being expressed, the levels of expression and how that expression changes over time.

The Proteomics Core focuses on the application of liquid chromatography and mass spectrometry to identify, quantify, and characterize proteins and post-translational protein modifications. Investigators in this division are involved in scientific collaborations with numerous Scripps Florida scientists as well as several outside investigators at other State and nationally recognized research institutions.

Drug Discovery. The objective of the drug discovery group is to translate basic research into potential therapeutics by integrating the work of the biomedical faculty, who provide therapeutic area expertise and in-depth knowledge of target biology, with the advanced technology group that helps enable target validation, assay development and biological models.