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The "Vitamin D and type 2 diabetes" (D2d Study) is a research trial, designed to see whether larger than typical supplements of vitamin D can prevent or postpone the onset of type 2 diabetes in people who are at high risk for type 2 diabetes.
The study was conceived, because vitamin D levels are often low in people who develop type 2 diabetes, and vitamin D has been shown in animal studies to increase insulin production and decrease the kind of inflammation in the body that produces resistance to the effects of insulin.
Though these findings point to potential benefit of vitamin D, proof of the benefit can only come from a well-done clinical trial.
The D2d Study enrolls volunteers with "pre-diabetes", those with higher than normal blood sugar that has not reached the levels required to diagnose diabetes. Volunteers are randomly assigned to receive vitamin D or inactive placebo.
Neither the volunteer nor the researchers are told which treatment the volunteer is receiving, so the result of the Study will not be biased. They will be followed for four years to assess the effectiveness of the treatment in preventing progression of pre-diabetes to diabetes.
The study is sponsored by the National Institutes of Health (NIH) and conducted locally by Maine Medical Center. Those interested in being screened for entry in the study are asked to call 207-661-7624 or write the researchers at d2d@mmc.org.
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