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Allan Sosin, MD
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Julie K. Harden, ND, LAc
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"In 2010 I crushed my calcaneus (heel) which had to be surgically repaired.  Two years later I started having severe arthritis in the subtalar joint as a result of the injury.  After using cortisone and being told I would need surgery to fuse the joint, I heard about Dr. Sosin through a friend and thought I would give it a try ... anything to relieve the pain.


Today after three shots I am much better.   Not perfect, but 60% better at least, and not taking any pain meds.  May not eliminate the need for surgery.  We'll see, but much better thus far.


Amazing result thus far."




Ozone Therapy


"There is a noticeable difference in my energy level and ability to take in air.  Especially when running!  I went for an 8 mile run this morning and didn't feel as winded.  It's helping me run longer distances without feeling tired or out of breath.  This week the change has been really drastic as I took last week off from ozone.  I continued to run last week but would get tired sooner.  There is also a difference in recovery time too.  After my longer runs (8-10 miles), it takes me a day or so to recover and I typically feel sore and stiff.  I felt pretty good after my run this morning and haven't experienced any soreness.  The last thing I've noticed is my minute per mile has improved.  It's shaved 40 seconds off my mile per minute time. (now 9:35/mi vs 10:15/mi.  Pretty neat actually.


Plus, I haven't felt the need to have coffee this week either.  This is strange for me as I typically drink 3-4 cups a day."



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Vol. 6 Issue #3 July 2013
Exercise Combats Dementia and Cancer


Many studies over the years have demonstrated that physical activities improve brain function.  Rats subjected to spinning and turning responded with a measurable increase in size of the part of the brain regulating balance.  My own experience with brain-injured  children over several decades, including those with autism, Down syndrome, cerebral palsy, traumatic injury, and others, revealed improvements in brain function directly corresponding to the amount of sensory, intellectual and physiological input, offered to the brain.


We have seen that individuals with dementia, when isolated and lacking human contact, recede into a vegetative state.  It is apparent that the brain grows through use, and withers when dormant.


A new study reveals the connection between fitness levels in mid-life and the incidence of dementia in the next 25 years. (Annals of Internal Medicine, 5 Feb 2013, pp 162-168)


There were 19,458 men and women, ranging in age from 45-50 years.  All had a treadmill stress test, with level of fitness determined by maximum time on the treadmill.


Subjects with the lowest level of fitness had the highest incidence of dementia after 25 years of follow-up, by which time all subjects were over 65 years of age.  There were 1659 cases of dementia.  Individuals with the highest level of physical fitness had a 35% reduced risk of dementia compared to those with the lowest exercise tolerance. This finding was independent of established cardiovascular risk factors, including history of stroke, high blood pressure, diabetes, cholesterol level, smoking and alcohol use.  Thus physical fitness by itself was a determinant of later-life dementia.


How to explain this?  Improved physical fitness protects against high blood pressure and diabetes.  Improved physical fitness is also associated with greater brain volume, which may enhance cognitive function.  Magnetic resonance angiograms (MRA) have shown an increase of small caliber vessels in the brain in exercising subjects, suggesting an increase in brain blood flow. One study in exercising mice revealed a decrease in amyloid, a protein found in degenerating brains, in the hippocampus and frontal cortex.  The hippocampus is involved in the formation of new memory, and the frontal cortex in judgment and cognitive processes.  


Fitness levels are modifiable through training.  Regular exercise for 2 1/2 hours a week for 5-6 months raises maximal oxygen consumption to permit a 1-2 MET increase in exercise capacity.  (One MET is the amount of energy generated at rest.  A person in good condition should be able to achieve 10 METS at maximal capacity.) 


The best way to improve fitness is to pursue activities you enjoy.  Unpleasant forms of exercise are unlikely to be maintained over time.  I swim 2/3 of a mile two or three times a week, ride my bike twelve miles once a week, partly up a very steep hill, and work out with stretching and light weights 5 days a week.  


Tango Dancers  

Recently my wife introduced me to tango, her personal intensive exercise.  Dancing can thoroughly satisfy the exercise requirement, and is also good for your soul.  Many of my patients do tai-chi, Pilates, yoga, mountain climbing or hiking, surfing, tennis, or volleyball.  Some do intensive structured anaerobic workouts. If you have more variety you can do something every day.


A correlative finding of the exercise study was a reduced incidence of lung and colorectal cancer in men who were at the highest level of fitness.  Compared with men in the lowest quintile of fitness, those in the highest quintile had a 67% reduction in lung cancer and 33% reduction in colon cancer incidence.  


In another article (Mayo Clin Proc, Jan 2013, pp11-21), the level of prostate specific antigen (PSA) was found to be lower in men who exercised more.  A one-hour daily increase in light physical activity reduced the risk of having an elevated PSA by 18%. Exercise may effect a lower risk of developing prostate cancer, inflammation, or enlargement.  It may also reduce the risk of having to undergo painful diagnostic biopsies.


Exercise works to accelerate metabolism of toxic substances, enhance immune function, and reduce the stress known to aggravate any medical condition.  For all these reasons, and to help you feel better, utilize exercise as a core strategy for health.




Allan Sosin MD 


Always Remember Magnesium

Healthy Woman I often take magnesium for granted, assuming that everyone takes it every day, like I do.  Not everybody does.  It would be good, then, to review what magnesium can do for you.


Of all the body's minerals, magnesium is the one most likely to be deficient.  It is required for over three hundred metabolic functions, including the utilization of cellular production of energy. Almost any gastrointestinal disturbance can cause depletion, including vomiting, diarrhea, inflammatory bowel disease, or malabsorption.  Diabetes mellitus causes magnesium deficiency through urinary losses, which in turn worsens diabetes.  Magnesium deficiency is found in 80% of people with depression. Diuretics, antibiotics and anti-cancer agents can cause depletion as well.  


The recommended daily magnesium intake is about 400 mg.  Refined foods are often low in magnesium.  Eighty-four percent of the magnesium in whole wheat is lost in the conversion to refined flour. The best food sources of magnesium are vegetables, beans and seeds: spinach, Swiss chard, figs, black beans and navy beans, sunflower and flaxseeds.


The blood level of magnesium should be over 2.0 meq/liter.  Below 1.5 meq/liter symptoms of leg cramps, weakness, fatigue, and palpitations are likely.  Symptomatic cardiac irregularities such as atrial fibrillation or atrial or ventricular arrhythmias may occur.


Magnesium is beneficial for these conditions:

  • High blood pressure
  • Heart rhythm irregularities
  • Coronary heart disease
  • Heart failure
  • Fatigue
  • Fibromyalgia
  • Muscle cramps or aching
  • Constipation
  • Toxemia
  • Seizures
  • Diabetes mellitus
  • Many neurologic conditions, including stroke and Parkinsons disease
  • Osteoporosis 
  • Asthma
  • Migraine (daily magnesium citrate intake of 600 mg reduced migraine frequency by 40%)

Oral magnesium is available in several forms, all of them effective.  However, some forms such as magnesium oxide or magnesium citrate are less well absorbed and more likely to cause diarrhea.  Chelated magnesium is better tolerated.  We usually start at 200 mg daily of elemental magnesium and go up as needed.  In patients with seizures or cardiac arrhythmias we use higher doses, up to 500-600 mg daily.  Onset of diarrhea is often the limiting factor in determining dosage.  As long as kidney function is normal, any excess magnesium will be excreted and not build up in the body.


We often give magnesium intravenously to ill or dehydrated patients, combined with other nutrients, and to those with heart rhythm abnormalities.  I have seen atrial fibrillation convert to normal rhythm in several patients, and IV magnesium is safe. Also, magnesium in liquid form can be taken by nebulizer to help relieve asthmatic symptoms. 


Magnesium can be taken at night to help with sleep, and it will also reduce the frequency and severity of nocturnal leg cramps.  I have been taking it at night in powdered form, for years, as a sleep aide.  


Magnesium should be included in any regimen of nutritional supplementation.  It should be a routine natural adjunct in the treatment of high blood pressure, diabetes, osteoporosis, and seizure disorders. 




Dr. Sosin Signature

  Allan Sosin MD


Tardigrade: The Ultimate Survivor


We read about people who exist in the extremes of environment: natives high in the mountains of Peru and Nepal, where oxygen is scarce; bushmen in the Kalahari Desert, who rarely drink water; Eskimos in the Arctic, who can function in debilitating frigidity.  


Other forms of life have their own environmental challenges.  The July 2013 issue of the National Geographic offers a 2-page color-enhanced electron microscope photo of a most remarkable creature: the tardigrade.  Also called a water bear, it is half a millimeter long, with eight legs and a mouth that looks like a fire hose nozzle.


The tardigrade can exist in temperatures approaching absolute zero (-200 degrees Centigrade), and in heat above boiling (150 degrees Centigrade).  It can tolerate a pressure of 6,000 atmospheres, more than the deepest part of the Pacific Ocean.  It can be exposed, without dying, to 1000 times more radiation than a human being.  It can live for 10 years without water, while changing its body composition from 85% to 3% water.


The tardigrade is an exceptionally hardy animal.  It demonstrates that life has the capacity to survive. We humans, in our advanced position on the evolutionary line, also possess, innate to our existence, the urge to survive. That truth, however, may be obscured by adversity and disappointment, leading us to diminish our estimates of ability, and our hopes.


At times of stress, we should remind ourselves that we are more resilient and more durable than we realize.  I have seen many people emerge at the other end of physical and emotional catastrophe.  A 90 year-old man lingering on a ventilator for three months with respiratory failure from pneumonia, recovers to roll his walker across the street to his favorite store.  An 80 year-old woman with metastatic breast cancer endures surgery after surgery to remove tumors from her body, still married and still active after 20 years.  A boy with severe cerebral palsy grows up to become the sports writer he was told he would never be.


Like the tardigrade, but in our own way, we know how to survive.



Allan Sosin MD 


July Supplement Special

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  • Myomin
  • Somnus
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  • Hylunia Facial Day Lotion (In-Office Only)  
Order online and use coupon code 7000 on checkout, or call 949-600-5100 to order by phone 




                               Discounts expire July 31st, 2013. Cannot be combined with any other offer.
The information contained in this e-mail is included for educational purposes only and is not intended to diagnose, treat or cure any disease. The above recommendations have not been reviewed by the U.S. Food and Drug Administration (FDA). Do not attempt to increase, reduce or discontinue the use of any medication except under the direct supervision of a physician. Unsolicited e-mail may not be answered and is not a substitute for obtaining medical advice in person from a qualified health professional.