Research News
MEDICAL SCHOOL OFFICE OF RESEARCH
May 2016

EVENTS 
Monday, May 9 - 
Thursday, May 12
Four-day workshop
9:00 AM - 5:00 PM
Kellogg Eye Center


Tuesday, May 10
Forum Hall,
Palmer Commons

This event is free and open to the public.


Tuesday, May 17
(breakfast provided) or
(lunch provided)
BSRB Seminar Rooms


Wednesday, May 18
9:00 AM - 1:00 PM
NCRC Bldgs. 10 & 18

RSVP required.
Please email Pam Campbell to register.


Tuesday, May 24
3:00 PM - 5:00 PM
Kahn Auditorium, BSRB


Wednesday, June 1
9:00 AM - 1:00 PM
Michigan League
Monday, June 6
7:30 AM - 5:00 PM
Ann Arbor Marriott Ypsilanti at Eagle Crest


Tuesday, June 7
12:00 PM - 1:00 PM

Please note: registration for this event is required.


Tuesday, June 14
8:00 AM - 12:00 PM
Forum Hall,
Palmer Commons


Tuesday, June 28
8:00 AM - 4:30 PM
BSRB Seminar Rooms

Both breakfast and
lunch will be provided.


SAVE THE DATE!
Wednesday, August 31
11:00 AM - 2:00 PM
Circle Drive in front of Med Sci I


RESEARCH NEWS 

QUICKLINKS
Fact Sheets
& Hot Topics

Find UMHS facts and figures for your next proposal!

Research Project
Route Map


Research Funding
& Grants Guide


MBECT Resources 

 

UMMS Office

of Research

 

U-M Medical School

 

Competition Space

 

IN THIS ISSUE 
 
Funding
  • Policies
  • Training & Professional Development
  • Announcements
  • FundingOpps
    Select Research Funding &
    Award Opportunities
    Pilot Grants

    External Limited Submissions
    Bridging Support
    Award
    Deadline
    BMRC Bridging Support
    for Biomedical Research
    Wednesday, June 15

    Other Opportunities

    Featured Foundation Grants

    Visit the UMHS Corporate and Foundation Relations website for more foundation funding opportunities.

    For additional details about funding resources, please visit the
    U-M Library's
    Research Funding & Grants Guide
    AAHRPP
    AAHRPP Site Visit Update
    The U-M's Association for the Accreditation of Human Research Protection Programs (AAHRPP) site visit was completed on Friday, April 1. At the closeout debrief, the AAHRPP site visit team presented a very positive report. 
        
    The site visit team had one (only one) observation to which U-M must respond by Thursday, May 5.
    The area they identified as needing improvement involved decisions of approvals with contingencies that might have been more appropriately identified as requiring deferral of approval. 
        
    The AAHRPP site visitors had many positive comments on
    U-M's Human Research Protection Program (HRPP), including:
    • the strategic and integrative nature of our HRPP,
    • our well-trained and motivated HRPP staff and
      IRB members,
    • our well informed investigators,
    • our education programs, and
    • our integrated website.
    Many thanks to everyone who contributed to this positive outcome. 
        
    We expect our final reaccreditation determination to be provided by the AAHRPP Council in mid-June. 
    MCTI.RFP
    RFP for Therapeutic Innovation Fund
    Proposals due Friday, June 17
    The Michigan Center for Therapeutic Innovation (MCTI) and Fast Forward Medical Innovation (FFMI) offer a five-year, $2.5 million fund created to accelerate the discovery and translation
    of therapeutic candidates at the University of Michigan. 

    Request for Proposals! 
       Submission Deadline: Friday, June 17 by 5:00 PM 
       Eligibility: Open to investigators across U-M

    The fund supports the discovery and optimization of small molecule lead compounds for projects with a specific, novel, and testable drug discovery hypothesis. Selected projects receive funding and resources from MCTI in the areas of drug design, cell biology, medicinal chemistry, structural biology, and pharmacology (up to $100,000 in value for each award for one to two years). The fund is jointly administered by MCTI and FFMI. 

    An advisory committee of recognized drug discovery and development experts will review and select projects for funding, and MCTI and FFMI will partner to assign funded teams with experienced mentors to guide each individual project. 
        
    Schedule your pre-submission meeting today!
    Contact Dr. Ester Fernández-Salas, MCTI Managing Director, at [email protected] or (734) 998-8301, or Casey Wegner, Senior Business Analyst, at [email protected] or (734) 764-2695.
    BRCF
    Meet with All of the Biomedical Research Core Facilities in One Room
    Join us on Thursday, June 2 at Palmer Commons
    Are you interested in learning more about Single Cell Analysis? Did you know that we have an Epigenomics Core, or that you can purchase more than 700 stocked items at five locations at our Biomedical Research Store?

    Next month, you'll have a unique opportunity to answer these questions and network with the Biomedical Research Core Facilities (BRCF) and more than 25 partner vendors at the BRCF Technology & Services Showcase:

    Thursday, June 2
    Palmer Commons
    10:00 AM
    Speaking Sessions Begin

    11:30 AM
    Exhibit Hall Opens

    FREE lunch from Zingerman's Deli
    available with entry ticket

    Speaking sessions featuring top experts in biomedical research will be held in Forum Hall, across from the vendor area. Sessions include:

    10:00 AM - 11:00 AM:

    Karin Hardiman, M.D.,
    Assistant Professor of Surgery
    in the Division of Colorectal Surgery, will present on her work with colorectal cancer, tumor heterogeneity, and subclonality

    11:00 AM - 11:30 AM:

    "Identification of Low Abundance Proteins in a Highly Complex Sample" from Proteomics & Peptide Synthesis Core Director Henriette Remmer, Ph.D.
    1:30 PM - 2:00 PM:

    Discussion on STED Depletion Microscopy with Linda Barthel,
    Lead Research Laboratory Specialist, 
    Microscopy & Image Analysis Laboratory, MIL North
    2:00 PM - 2:45 PM:

    "CRISPR/Cas9 Systems:
    CRISPR Activators, Synthetic CRISPR, and the CRISPR Core Partnership Program" with Tom Lanigan, Ph.D., Director of the Vector Core, and Chris Lemke, Scientific Liaison, MilliporeSigma

    Visit the event website for a full list of participating vendors and Core exhibitors.
    Lab.Transport
    Your Lab is Spending HOW MUCH to Transport Samples Across Campus??
    Did you know that biological samples are prohibited on public buses (including AATA and U-M passenger buses), taxis/ubers, personal cars, and non-DOT regulated motor vehicles on public roads?

    Did you also know that improperly transporting samples can potentially cause personal injury as well as result in significant fines by the Department of Transportation? 

    U-M has three compliant, convenient, and cost-effective options for researchers to quickly get biological samples where they need to go around the U-M campus.

    CLICK HERE for more information about each OSEH-approved transportation option, including a side-by-side comparison chart.
    MICHR
    Apply by Friday, May 13 for MICHR Community-University Seed Funding
    & Health Research (MICHR) is now accepting applications for a funding opportunity designed to support community-engaged research partnerships and projects addressing community-identified health priorities in communities across Michigan. 
        
    The Community University Partnership Seed (CUPS) Award (up to $5,000) is open to both newly forming and previously established partnerships and will support a variety of partnership activities, such as: 
    • Developing a steering committee or other partnership infrastructure; 
    • Disseminating and translating research findings; 
    • Evaluating the partnership process. 
    CUPS applications will be accepted on a rolling basis. Applicants that would like to be considered during the upcoming round of review will need to submit their applications by Friday, May 13. 
        
    To learn more about how to apply and view the request for applications, please visit MICHR's Communities Engagement web page or contact Adam Paberzs at [email protected].
    ACUO
    Help Inform Future Communications and You Could Win $50 from Amazon!
    has crafted a brief customer satisfaction survey to better understand our research community's communication needs and usage habits as they pertain to animal care and use at U-M.

    (or paste bit.ly/acuo-comm into your web browser)

    The results will inform efforts to re-design the website and to refine communications to the U-M community. Plus, every person who submits a completed survey will be entered automatically in a prize drawing to win a $50 Amazon.com gift card!

    Thank you for your feedback.
    MedMI
    Medicine at Michigan Seeking Publications, Apps by Faculty
    Submissions due by Wednesday, June 1
    The Medicine at Michigan website is currently seeking news of publications written or edited by faculty.

    They are also interested in featuring faculty-developed health apps.

    For publications: 
    Please send title, co-authors/editors, publisher, and publication date to Lauren Crawford by June 1 for inclusion on the website. If possible, please also include a high-resolution image of the cover. 
    For mobile apps:
    Please send a short description about the purpose and intended audience of the app, as well as screenshots and/or logos, to Lauren Crawford by June 1 for inclusion on the website.
    If you have any questions, please contact Lauren Crawford at [email protected].
    MNORC
    Metabolic Test Kitchen Available
    to Meet Your Research Needs
    Are you designing a research study involving dietary, physical activity/exercise, body composition, and/or metabolic measurements or interventions in human subjects?

    The Michigan Nutrition Obesity Research Center (MNORC)'s Human Phenotyping Core (HPC) provides the following services: 
    • Consultation services to investigators. The HPC has the expertise to help you optimize the design of your study. 
    • Standardized and sophisticated assessment and physiological testing of human subjects. The HPC has the equipment and the expertise to implement a wide array of nutritional assessments and physiological/metabolic tests for your research studies. 
    • Services to directly assist researchers with conducting their nutritional and/or exercise interventions in human subjects. 
    Not sure how these services may apply to your study? 
    Recently, the HPC metabolic test kitchen began prepping for an intensive feeding study looking at the effects of a high-fat vs. high-carbohydrate diet on responses of the metabolome.

    With dietitians and technicians on staff, we are able to design five-day rotating menus for both study conditions that are calorie controlled to the study participant to prevent changes in weight.
    In addition, we procure and prepare the food for pickup using standardized weighing and menu development techniques. 

    For more information, including a complete list of services, please visit the MNORC website or email the Core
    Foundation
    Featured Foundation Grants
    for Biomedical Research 
    null
    UMHS Corporate and Foundation Relations would like to draw your attention to the following foundations who currently have open RFPs for biomedical research grants:

    James S. McDonnell Foundation -- Postdoctoral Fellowships
    The James S. McDonnell Foundation (JSMF) Postdoctoral Fellowship Award in Studying Complex Systems provides fellowships to students completing doctoral training in the multidisciplinary field of complex systems science. 

    Award
    Amount
    Deadline
    $200K
    Thursday, June 30
    by 4:59 PM EST
    The total amount of the JSMF Fellowship is to be expended in no less than two and no more than three years.

    Reflex Sympathetic Dystrophy Syndrome Association Research Grants
    The Reflex Sympathetic Dystrophy Syndrome Association (RSDSA) welcomes letters of inquiry throughout the year regarding possible basic science or clinical research projects that advance the understanding of Complex Regional Pain Syndrome/Reflex Sympathetic Dystrophy Syndrome

    Award
    Amount
    Deadline
    $100KRolling basis

    International Mental Health Research Organization -- Rising Star Awards
    The International Mental Health Research Organization (IMHRO)'s Rising Star Awards aim to encourage the community of neuroscience researchers to direct their efforts toward basic, translational, and clinical science while supporting the research of emerging leaders in the field. 

    Questions about these award opportunities should be directed to Joe Piffaretti in UMHS Corporate and Foundation Relations via email at [email protected] or phone at (734) 763-1318.

    If you are interested in receiving weekly funding announcements that include opportunities such as those listed above, please contact Joe Piffaretti to be added to the faculty/staff email circulation list.
    SharpFocus
    New NIH Rigor Standards: Authentication of Key Biological and/or Chemical Resources
    Sharpening Your Focus:
    Tips on Grant Proposal Preparation
    By Jill Jividen, Ph.D., Senior Manager
    for Research Development Support,
    U-M Medical School Office of Research

    (One in a series of tips published in UMMS Research News about writing proposals.) 

    The National Institutes of Health (NIH)'s 2016 Rigor & Reproducibility criteria require a new attachment to the updated SF424 form (soon to be FORMS-D). This document, called "Authentication of Key Biological and/or Chemical Resources," asks researchers to detail plans for authenticating resources that are integral to the proposed research -- resources that may differ from lab to lab (or over time), or have qualities that might influence results. Those resources include (but are not limited to) cell lines, specialty chemicals, reagents, antibodies, or other biologics.

    According to NIH instructions, the document should be brief --
    a page or less -- and should be limited to an investigator's plans to authenticate during the course of the project (not the actual results or data of resources already authenticated). Examples include plans to use flow cytometry or immunohistochemistry to identify primary cell lines, or using western blot analysis for antibody specificity.

    Study section members will be asked to review this document, but at this point it will not affect impact scores. They may follow up with questions if more information is needed on meritorious proposals.

    The challenge, NIH has acknowledged, is that there is a lack of standards and best practices for authenticating some of the relevant resources. It is a hope that this push toward transparency and detailed reporting of practices will build a consensus in the research community around best practices for authenticating critical scientific resources.

    For more information:

    Our mission in the Office of Research is to foster an environment of innovation
    and efficiency that serves the U-M Medical School community and supports
    biomedical science from insight to impact.