Gene-editing technique offers hope for hereditary diseases
From left: Juan Carlos Izpisua Belmonte, Alejando Ocampo, Pradeep Reddy

For thousands of women around the globe carrying a mitochondrial disease,

having a healthy child can be a gamble. Now, Juan Carlos Izpisua Belmonte's laboratory developed a technique using molecular "scissors" to eliminate mitochondrial mutations in eggs and early embryos in mice. This gene-editing technique, detailed in Cell, has the potential to prevent babies from inheriting mitochondrial diseases.


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Press release:Salk scientists use molecular "scissors" to eliminate mitochondrial mutations in eggs and embryos


Select media coverage:  Scientific American, New Scientist, The GuardianAAAS/Science News, KPBS

Hundreds come out for a day of scientific exploration at the third annual Explore Salk


Hundreds of science and Salk Institute enthusiasts came out for a day of fun and discovery at the third annual Explore Salk on April 11. Throughout the six-hour event, the campus was buzzing with activity. Lab tours were available to adults and teens; young attendees kept busy with hands-on activities in the Kids' Discovery Zone; and science booths, staffed by Salk scientists, offered highlights from specific research areas. Topping off the day were two science talks: one by Salk Assistant Professor Saket Navlakha and the other by special guest speaker Eric Topol.


Special thanks to all of the volunteers and staff who helped make Explore Salk a fun and educational event for the community. Many thanks also to our sponsors, including our title sponsors Merck, Kyxy 96.5 and Waxie, for helping to make the day a tremendous success.  

Click here »  to view a photo gallery from the day.

Salk News

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How the brain balances risk-taking and learning 

Salk researchers Sreekanth Chalasani and Tatyana Sharpee discovered a learning circuit in roundworms that gives clues to human behavior, as detailed in Neuron. The new work reveals the function of two chemical signals critical to human behavior: dopamine----responsible for risk-taking----and CREB----needed for learning.

Press Release: How the brain balances risk-taking and learning

Select media coverage: Health CanalMedical Xpress


Food for thought: Master protein enhances memory

ERRγ is shown (stained red) in the hippocampus, the area of the brain largely responsible for memory.

Salk scientists in Ronald Evans' laboratory discovered that physical and mental activities rely on a single metabolic protein that controls the flow of blood and nutrients, as reported in Cell Metabolism. The lab had previously discovered that this protein supplies energy to the muscles. In the new work, the team showed this protein is also crucial for energizing brain cells, suggesting that it could be useful for boosting learning and memory.


Press Release: Salk scientists discover a single protein that energizes both muscles and the brain

Select media coverage:  R&D MagazineNews Medical

Watch for the new issue of

Inside Salk coming soon! 

The spring issue highlights some of the significant advancements in discovery that have developed from the "culture of collision" at the Institute.

Interested in getting on our mailing list to receive the print version of Inside Salk?

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Other Salk News

Congratulations new AAAS members!

Congratulations to Joseph Ecker and Dennis O'Leary for their election into the American Academy of Arts & Sciences (AAAS), where they join over a dozen other Salk faculty and some of the world's most accomplished leaders from academia, business, public affairs, the humanities and the arts.

Terrence Sejnowski - Peggy Peattie
Your Brain: A Special Report 
From embryo to old age, from its diseases to its future, the brain is the subject of a special 52-page U-T San Diego section, "The Wonders of Your Brain." Essays, explanatory information and scientific images provided by Salk scientists Terrence Sejnowski, Fred Gage, Ed Callaway, as well as William Brody, are featured prominently in the report produced by science reporter Gary Robbins and photographer Peggy Peattie.

To read "The Wonders of Your Brain," as well as view bonus videos and photographs, click on » 

Read President Brody's essay: Has the decade of the brain finally arrived?

Read Professor Sejnowski's essay: Tune-ups for your Ferrari of a brain

There's a lot to LIKE

There's a lot to like about the Salk Institute's Facebook page. Arty shots of the campus architecture at sunset, historical glimpses of the Institute's early years, an exciting events calendar and, best of all, the latest information on influential biological discoveries made by Salk's renowned scientists.

You love us for our science. Now, Like us on Facebook. All it takes is a simple little click right here »

Upcoming Events

Salk Science & Music Series

April 26, 2015 Sold Out

Fei-Fei Dong and
Juan Carlos Izpisua Belmonte
Conrad T. Prebys Auditorium

Salk Institute

Purchase tickets » 


43rd Annual Tax Seminar for Private Foundations

May 11 -13, 2015

Information and registration » 

Salk Science & Music Series

June 7, 2015

Brubeck Brothers Quartet & Satchin Panda

Conrad T. Prebys Auditorium

Salk Institute

Purchase tickets » 


Symphony At SalkSave the Date 

August 29, 2015

Salk science image for download 
Decorate your desktop, tablet or smartphone with some of the most intriguing images from the Salk Institute! 

This image of neurons was created using brain mapping technology developed by Salk Professor Ed Callaway. The technique uses a modified rabies virus to illuminate the connections between neighboring neurons in the brain. This image was recently featured in the U-T San Diego's special section on the brain.


 Click here  »  for instructions and downloads.

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