KRIEGER

 
Mixing & Homogenising Systems 

    

Issue 16  
March 2013 
In This Issue
New Micro Mixer
In Line Monitoring (PAT)
Balanced Shear Force
Quick Links: 

 Krieger Homepage

kriegerswitzerland.com   

New Technologie
Contained Press

 

  • Completely Contained Processing  
  • Sterility Assurance Level 100%  
  • Double Mechanical seals for 4 bar  
  • Counter rotatingdesign (low and high speed) 
  • No sealing liquid barrier system  
  • No sterilisation of cooling liquids required  
  • CIP/SIP design, no dismantling required
  • Find out more
        on our website    
    Micro Mixer
    micro mixer
    Bottem Driven 200ml
    Find out more
         on our website    
     Data Sheet
    European Version

    data sheet EU  

    Find out more
         on our website    
     Data Sheet
    American Version  

    data sheet US 

    Find out more
         on our website    
    Download
    URT
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    Dear Customer,

     

     Our aim is to develop "state of the art" mixing and homogenising equipment.

     

    In this newsletter we report on a new fascinating product that will facilitiate drug development performed on a small laboratory scale:

     

    The new Micro Mixer.

     

    Furthermore we take a look into our progress to date at our research program to develop an inline (PAT) measurement system for monitoring the homogenising process.

     

    We hope our innovative products and upcoming product pipeline will inspire you to

    "discover new horizons".

     

    Yours faithfully

     

    Krieger AG 

     

    Guy Akkermans                             

    CEO

     

    Micro Mixer

    Top Driven 200ml

    Seamless mixing of small batches under vacuum or pressure with validated mixing speeds and temperature control are all combined now in one device:

     

    The Krieger Micro Mixer

     

    The Micro Mixer allows researchers fast drug development tests on the smallest scale, where controlled process conditions are a stringent requirement.

    The portable vessel can be filled or emptied under an isolator or glove box.

     

    Visit our website for more information and to download the data sheet

    In line monitoring (PAT) of the homogenising process

    Together with our research partner, the Institute for Pharma Technology, Krieger is further developing a "real time" monitoring system for the homogenising process.

     

    Measuring instruments includes ultrasound resonator technolgy, a flow through coriolis force sensor and a few more,...

    Results show that the homogeneity status can be well monitored.

     

    Besides a final end point determination of the homogenising process, many different data can be monitored including detection of differences in the quality of the raw materials used.

    Mi Molto    

    Balanced Shear Force

    The research of the Institute for Pharma Technology proved and documented the renowned Krieger C- TF homogenisers "Balanced Shear force" characteristics.

     

    Balanced shear force combines fast homogenisation times with shear forces that keep intact the characterisitics of API's when the homogenising process runs for a longer time span.

     

    A next step in research will be done with a shear sensor that will be used to determine the effect of different shear stress situations on the homogenisation process.