WHAT'S NEW WITH DART® MS?                                    September 2014  
 The Latest Developments in Direct Analysis in Real Time Mass Spectrometry 

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We have three new application posters and notes that we want to share with you.  The two posters, SPME-DART of Beer and Profiling of Milk are from the recent AOAC meeting.  The application note on Rapid Identification of Contaminants in Water using the DART-Orbitrap combo is from our colleagues at Thermo.

Additionally we have an updated version of the DART Book of Food Abstracts available for downloading and there are several new publications this month.

 Feel free to contact me if you have any questions or comments.  Thanks.


Brian Musselman, Ph.D.
President and CEO

Recent Posters from AOAC 2014


Here are two posters we presented at  the AOAC meeting in Florida this month.  The first poster shows how using solid phase micro extraction with DART analysis provides a rich fingerprint of beer, showing the various types of beer as well as the degradation of hop acids.  In the second poster, statistical modeling of the DART data is able to provide a predictive model that can show milk quality as well at authentication.






The New Application Note from ThermoScientific on the DART-Orbitrap



This note shows how DART with the high-resolution Orbitraptm mass spectrometer can rapidly and confidently identify a broad range of pesticide contaminants in water down to levels of 1 ng/ml.   


The work was done in collaboration with Jaewon Choi and Wonseok Choi of the Water Analysis & Research Center of K-Water in Daejeon, Korea  




New Version of the DART Abstract Book of Food Safety and Quality Available

We have a new version of the DART Abstract
Book of Food Safety and Quality for you to download.  It has over 40 recent abstracts dealing with a range of problems - from pesticide and drug contamination to authentication and quality of beverage and supplements.  Click the link below or the image to download a copy.



Recent DART Publications

Solid phase microextraction (SPME)-transmission mode (TM) pushes down detection limits in direct analysis in real time (DART)


Germán Augusto Gómez-Ríosa and Janusz Pawliszyn  

Department of Chemistry, University of Waterloo, Waterloo, Canada  


A new SPME device was developed and applied for quick solventless extraction/enrichment of small molecules from complex matrices. Subsequently, the device was coupled as a transmission mode substrate to DART resulting in limits of detection in the low pg mL−1 level in less than 3 minutes with reproducibility below 5% RSD.  

Jürgen H. Gross
Institute of Organic Chemistry, Heidelberg University, Heidelberg, Germany

Direct analysis in real time mass spectrometry (DART-MS) has become an established technique for rapid mass spectral analysis of a large variety of samples. DART-MS is capable of analyzing the sample at atmospheric pressure, essentially in the open laboratory environment. DART-MS can be applied to compounds that have been deposited or adsorbed on to surfaces or that are being desorbed therefrom into the atmosphere. This makes DART-MS suitable and well-known for analysis of ingredients of plant materials, pesticide monitoring on vegetables, forensic and safety applications such as screening for traces of explosives, warfare agents, or illicit drugs on luggage, clothes, or bank notes, etc. DART can also be used for analysis of either solid or liquid bulk materials, as may be required in quality control, or to quickly investigate the identity of a compound from chemical synthesis. Even living organisms can be subjected to DART-MS. Driven by different needs in analytical practice, the combination of the DART ionization source and interface can be configured in multiple geometries and with various accessories to adapt the setup as required. Analysis by DART-MS relies on some sort of gas-phase ionization mechanism. In DART, initial generation of the ionizing species is by use of a corona discharge in a pure helium atmosphere which delivers excited helium atoms that, upon their release into the atmosphere, will initiate a cascade of gas-phase reactions. In the end, this results in reagent ions created from atmospheric water or (solvent) vapor in the vicinity of the surface subject to analysis where they effect a chemical ionization process. DART ionization processes may generate positive or negative ions, predominantly even-electron species, but odd-electron species do also occur. The prevailing process of analyte ion formation from a given sample is highly dependent on analyte properties.

About IonSense
IonSense, Inc. provides OpenSpot Mass Spectrometry™ solutions to the fields of food safety, forensics, drug development, and chemical analysis. We manufacture and develop direct analysis in real time (DART®) technology licensed from JEOL USA, Inc. and atmospheric solids analysis probe (ASAP™) licensed from M&M Consulting.

DART and ASAP Sources are available for most commercial LC/MS systems.  Look here to see if your system is DART-ready.  And  check here to see if your system is ASAP-ready.

For your local representative, please see our distributor network.

Phone - 781.484.1043  | |
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