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Hot off the presses! Neo 40 daily improves blood pressure, functional capacity, and quality of life.
Nitric oxide is an extremely important biochemical that declines with age and can be deficient due to many other factors. I devoted three newsletters to this "anti-aging" miracle molecule (beginning with this one).  A multitude of nutritional supplements purported to boost or supply nitric oxide are being heavily marketed. Some of these are comprised of ingredients that cannot possibly work- betraying the scientific ignorance of the creators of these heavily advertised products. Over the past 25+ years I have scrutinized the field of nutritional supplements to identify the best products (available on my online store).
When it comes to nitric oxide, Neo40 daily is the premier supplement. It was created by Dr. Nathan Bryan, one of the world's leading experts on nitric oxide. Neo40 daily is a lozenge, which actually produces nitric oxide on contact in the mouth and also contains ingredients to optimize the body's own nitric oxide production over time with continued use.
One would hope and expect a high-quality nutritional formula to be backed by research. This is certainly the case with Neo40 daily. It was found in a previous study to reduce excessive inflammation and blood triglycerides. Study participants commonly reported reduced stress and increased energy. There are several other studies underway or awaiting publication. The results of the latest study on Neo40 daily were just reported. (Biswas OS, Gonzalez VR, Schwarz ER. J Cardiovasc Pharmacol Ther. 2014 Jun 18. pii: 1074248414539563. [Epub ahead of print] ). In a nutshell, the study found that Neo40 daily:
- Improved both physical and mental wellbeing
- Lowered elevated blood pressure
- Improved functional exercise capacity
One of the most-studied effects of nitric oxide is its influence on blood vessel relaxation and dilation. A "nitric oxide supplement" would be expected to lower elevated blood pressure. This recent study on Neo40 daily was carried out on 30 subjects with prehypertension. About 2 out of 3 Americans have prehypertension or hypertension. Prehypertension is the stage of blood pressure between normal and hypertension, which most individuals experience before "graduating" to frank hypertension. Although "prehypertension" may not sound dangerous, it has actually been associated with increased risk to stroke and greater than three times increased risk to heart attack. Hypertension does damage to organs, including the heart, kidneys, eyes, and brain, and is the number one risk factor for death worldwide.
In this recent 30 day study, half the subjects received Neo40 daily and the other half received a placebo, taken twice daily. The subjects started with an average blood pressure of 138/84 (138 mm of mercury systolic and 84 mm of mercury diastolic). What magnitude of reduction in blood pressure is considered significant? A drop of just 5 mm of mercury is associated with lowered risks of ischemic heart disease by 21% and stroke by 34%. The DASH (Dietary Approaches to Stop Hypertension) diet is the mainstay of prehypertension treatment and lowers blood pressure by this amount.
In this study, Neo40 daily was found to lower blood pressure from 138/84 to 126/78, a reduction of 12 mm of mercury systolic and 6 mm of mercury diastolic.
BP Reduction: Neo40 daily vs Current Guidelines
| Therapy | Systolic BP Reduction | Diastolic BP Reduction |
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| Dash Diet | 5.5 mm Hg | 3 mm Hg | | Neo 40 | 12 mm Hg | 6 mm Hg |
Functional capacity was evaluated with the standard 6-minute walk test. The study participants who received Neo 40 daily experienced a significant increase in the achieved walking distance: an average of 596 meters at baseline and 650 meters at the end of 30 days.
Using a standardized questionnaire to assess quality of life, patients receiving Neo40 daily showed improvement in the Physical Component Summary Score (PCS) and Mental Component Summary Score (MCS).
I believe Neo40 daily is one of the most valuable nutritional supplements ever created. If you have hypertension or prehypertension you should take Neo40 daily. It is a top priority for anyone with low nitric oxide levels, which can be determined with Neogenis Test Strips.
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