Alzheimer's disease is a progressive, degenerative disease of the brain that results in impaired memory, thinking and behavior. Minor problems with memory, orientation and language appear initially. Patients steadily deteriorate over time and eventually become unable to care for themselves.
WHAT ARE SOME OF THE SYMPTOMS OF ALZHEIMER'S DISEASE?
There are some behavioral clues that may signal the onset of Alzheimer's disease. Common symptoms are:
- Forgetfulness, especially about recent events
- Language problems, such as trouble finding words
- Poor or impaired judgment
- Disorientation of time and place
- Changes in mood, behavior or personality
WHAT CAUSES ALZHEIMER'S DISEASE?
The cause of Alzheimer's disease is not fully understood and is the subject of intense scientific investigation. Just like people who have arthritis or migraines, no one is to blame.
HOW IS ALZHEIMER'S DISEASE DIAGNOSED?
Although recent advances have been made in the area of genetic diagnostics, there is currently no definitive clinical test available to identify Alzheimer's disease. The diagnosis is usually reached by ruling out other possible causes of the symptoms. Some treatable or reversible conditions such as depression, adverse drug reaction and metabolic changes can create symptoms confused with Alzheimer's disease. A physician can rule out other possible causes during a comprehensive evaluation. The evaluation should include:
- A complete medical history
- Neurological and physical examinations
- Mental status and/or psychiatric assessments
- Radiological brain study such as CT scan or MRI
WHAT IS A CLINICAL TRIAL?
A clinical trial is research study in volunteers conducted under the direct supervision of experienced physicians. These trials study new treatments following strict guidelines set by the Food and Drug Administration, (FDA). An independent group from the community called an IRB helps protect study participants by making sure the study is compliant with the law.
WHY WOULD I WANT TO JOIN A CLINICAL TRIAL?
It is natural to be a bit apprehensive about participation in a research study. Here are a few things many people don't realize about clinical trials:
- Study participants are closely monitored during the trial
- Study participants may receive medical tests and exams before, during and after the clinical trial.
- Some clinical trials study medicines that are already prescribed by doctors but are now being evaluated for a new use.
- Every life-saving medication that is available to the public only exists because of dedicated clinical trial volunteers
WHAT ARE THE BENEFITS OF PARTICIPATING IN A TRIAL?
People decide to participate in a clinical trial for a variety of reasons. Some of the reasons include:
- Receiving a study medication that could potentially improve the symptoms of Alzheimer's disease.
- The satisfaction of knowing they may ultimately help countless individuals struggling with Alzheimer's disease by advancing today's medical research.
- Access to no cost health assessments and investigational medicines before they become widely available.
- In addition, some studies compensate participants for their time and travel.
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