A dysregulated inflammatory response to endotoxin underlies many diseases.  Lipopolysaccharide-binding protein (LBP) is a component of the innate immune response that is upregulated during bacteremia or endotoxemia.  A recent study by scientists in Spain and published in PLOS-ONE showed high LBP levels in obese patients, suggesting that microbial exposure plays a role in obesity.

Determinants of Serum Concentrations of Lipopolysaccharide-Binding Protein (LBP) in the Adult Population:  The Role of Obesity

Scientists at BioDtech, Inc. have measured previously undetectable levels of endotoxin which could cause activation of the immune system.  BioDtech products are designed to more accurately detect endotoxin and remove it from proteins and DNA.