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April 2013

 

 

News

 


Geriatric Syndromes and Incident Disability in Older Women

The Journal of the American Geriatrics Society recently published a study that examined the number of geriatric syndromes associated with incident disability among community-dwelling older women.The study cohort consisted of 29, 544 older women ages 65 and older who reported limited disability at baseline.Geriatric syndromes such as depression, dizziness, hearing or visual impairment, osteoporosis, urinary incontinence, and polypharmacy were measured and later reassessed after 3- years to determine the progression of each condition.The authors found that "Geriatric syndromes were significantly associated with onset of disability in older women" and that "a better understanding of how these conditions contribute to disablement is needed."

 

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Pain Severity among Older Adults with Chronic Low-Back Pain

A study published in American Journal of Physical Medicine and Rehabilitation sought to determine whether " mobility and functional pain were different among older men and women with chronic low-back pain and varying body mass index levels." The study consisted of 55 older adults ages 60-85 years old. Participants completed a series of functional examinations that measured walking endurance, ability to climb stairs, and pain rating with activity. The study found that " functional pain scores during walking and stair climb were highest in the severely obese group compared with the overweight group, but the functional test scores were not found to be significantly different by body mass index."  

 

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Self-management Intervention for Pain among Older Adults

A recent article published in Pain compared an outpatient pain self-management (PSM) program with an exercise-attention control (EAC) programfor community-dwelling older adults. A total of 141 older adults with chronic pain conditions participated. The authors found that members of the PSM group were "significantly improved on measures of pain distress, disability, and unhelpful pain beliefs," in comparison to members of the EAC group. The authors conclude that, "in the short term at least, cognitive-behavioural therapy-based PSM was more effective than exercises and usual care."

 

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Factors Associated with Chronic Joint Pain among Older Adults

In Geriatrics and Gerontology International a featured study analyzed the "prevalence and factors associated with self-reported rheumatic diseases and chronic joint symptoms among older adults." The study involved 2209 older adults who completed a survey that evaluated sociodemographic factors, activities of daily living, chronic conditions, medications and quality of life.The authors determined that "cataracts and cardiovascular disease were associated with rheumatism" and that,"the identification of these characteristics in the elderly will contribute to a better understanding of rheumatic diseases and should be used to plan effective preventive measures."

 

Full Story 

 

 

 Upcoming Events

The following list includes upcoming seminars, meetings, and conferences that  focus on aging, pain, or general research methods


April Work-in-Progress Seminar  

TRIPLL will host a WIP seminar on April 24, 2013. Please note that the WIP date has been postponed due to a scheduling conflict. To participate, contact Marcus Warmington at [email protected] if you have any questions or would like to participate in future WIPs.  

 
TRIPLL Webinar Series

Managing Refractory Pain in Patients with Musculoskeletal Disorders
Friday, April 19, 2013  1:00pm - 2:00pm EST 

Presenter: Stephen Paget, MD, Physician in Chief Emeritus, Prior HSS Chairman of the Division of Rheumatology, Director of the HSS Rheumatology Academy of Medical Educators and the Stephen A. Paget, Rheumatology Leadership Chair.

Overview: This webinar will focus on the diagnostic algorithms and treatment options employed in the setting of acute and chronic pain syndromes that arise in a broad range of patients with musculoskeletal and systemic autoimmune/inflammatory disorders. 

 

Movement & Meditation to Ease Chronic Pain
When living with pain, it is easy to find yourself avoiding daily activities, opting to stay still and avoiding unnecessary movement. Unfortunately, not moving your muscles and joints often leads to more pain. Let's get moving! Join us for this gentle class that will utilize the movements of yoga and stretching in addition to breathing awareness and meditation to help ease stiffness, aches and pains.
For more information: www.hss.edu/pped or (212) 606-1613.

The Faculty Development Collaborative Program in Geriatrics

is a training program designed to enhance the knowledge and skills of health professions faculty in inter-professional teaching, leadership, project development and program implementation in geriatrics. This course will prepare health professions faculty from multiple disciplines to utilize contemporary evidence-based educational strategies, inter-professional team approaches, and innovative evaluation processes in teaching collaborative patient- centered care.

   

 

Funding Opportunities

 

Pain-Related Funding

 

 

Pain in Aging (R01)

Program Announcement (PA) Number: PAR-10-282 

"This FOA encourages Research Project Grant (R01) applications from institutions/organizations that propose to study pain from an aging perspective, including studies of older populations, studies of age differences and age-related changes in pain processes and experiences, and studies of pain treatment and management in older adults. This FOA particularly encourages studies on 1) mechanisms and predictors of pain experience in aging, 2) development and evaluation of pain assessment tools for older adults or older model organisms, and 3) development and evaluation of pain management strategies in older adults, with particular attention to the challenges associated with treating pain in patients with multiple morbidities. Studies may address a variety of approaches and outcomes including biological (i.e., genetic, molecular, neurobiological), clinical, behavioral, psychological, and social factors.  Both animal models (especially aged animals) and human subjects are appropriate for this FOA."    

 

To Register 

 

Pilot and Feasibility Clinical Research Grants in Arthritis and Musculoskeletal and Skin Diseases (R21)
Program Announcement (PA) Number: PAR-10-282
"This FOA, issued by National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) of the National Institutes of Health, encourages exploratory/developmental clinical research related to the prevention or treatment of arthritis and musculoskeletal and skin diseases, conditions, and/or injuries. The Pilot and Feasibility Clinical Research Grants Program is designed to allow initiation of exploratory, short-term clinical studies, so that new ideas may be investigated without stringent requirements for preliminary data. The short-term studies should focus on research questions that are likely to gather critical preliminary data in support of a future, planned clinical trial.  They can include testing new or prevention strategies, a new intervention, or unique combinations of therapies.  A high priority is the use of such studies to help stimulate the translation of promising research developments from the laboratory into clinical practice."

To Register 

 

Mayday Fund of New York
"The Mayday Fund is dedicated to alleviating the incidence, degree, and consequence of human physical pain.

The Mayday Fund's current grant-making targets are projects that result in clinical interventions to reduce the toll of physical pain, pediatric pain, pain in non-verbal populations, and pain in the context of emergency medicine. Mayday will also continue to be proactive in its commitment to promote networking between veterinary and human medicine, especially in an effort to inform measurements of pain in non-verbal populations. Finally, the trustees of the Mayday Fund wish to be nimble enough to respond as special opportunities present themselves. Grants are made only to public charities and educational institutions officially recognized as such by the IRS. The Mayday Fund concentrates its activities in the United States. On occasion, grants have been made to Canadian organizations when the project has an effect that reaches beyond Canada. Grants cannot be made to individuals."

 

Applications are continuous and no specified due date is applied.

 

 

Age-Related Funding

 

 

Translational Research at the Aging/Cancer Interface (TRACI) (R01)

Program Announcement (PA) Number: PA-12-136

This Funding Opportunity Announcement (FOA) encourages translational research proposals in the overlapping areas of human aging and cancer, linking basic and clinical research relevant to the care of older cancer patients through both bench-to-bedside and bedside-to-bench approaches. Ultimately, information from the research supported by this initiative should improve the health and well-being of elderly patients at risk for, or diagnosed with, cancer and decrease the functional impairment and morbidity associated with cancer in this population.    

 

T1 Translational Research:  Novel interventions for prevention and treatment of age-related conditions (R21)

Program Announcement (PA) Number: PAS-11-280

This funding opportunity announcement (FOA) encourages exploratory/developmental R21 research projects to accelerate the pace of development of novel therapeutics involving biologics, pharmacological and non-pharmacological approaches for preventing and treating key health issues affecting the elderly.   For the purposes of this FOA, T1 translational research on aging is defined as the application of basic and clinical biomedical findings towards the development of new strategies for prevention and treatment of age-related pathologies. For projects proposing basic research that is being conducted in animal models, the potential to treat a clinical age-related pathology must be clearly stated in the proposal.  Direct relevance of the data to a clinical aging condition must be established and clearly stated in the application.


Translational Research to Help Older Adults Maintain their Health and Independence in the Community (R01)

Program Announcement (PA) Number: PA-11-123

The National Institute on Aging (NIA) and the Administration on Aging (AoA) invite applications using the R01 award mechanism for translational research that moves evidence-based research findings towards the development of new interventions, programs, policies, practices, and tools that can be used by community-based organizations to help elderly individuals remain healthy and independent, and living in their own homes and communities.  The goal of this FOA is to support translational research involving collaborations between academic research centers and community-based organizations with expertise serving the elderly (such as city and state health departments, city/town leadership councils, and Area Agencies on Aging) that will enhance our understanding of practical tools, techniques, programs and policies that communities across the nation can use to more effectively respond to needs of their aging populations.

 

Mechanism Mediating Osteoarthritis in Aging
Program Announcement (PA) Number: PA-12-018
"This Funding Opportunity Announcement (FOA) issued by the National Institute on Aging (NIA) and the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) invites applications on research employing genetically defined and modified mouse models, other animal models such as dogs and monkeys or archived human joint tissues to explore the biological mechanisms underlying osteoarthritis.  Osteoarthritis is a significant problem in the elderly population, and a major contributor to mobility limitations that are endemic in this population and, therefore, is an important element in the research missions of NIA and NIAMS. Inflammatory processes are evident in advanced stages of osteoarthritis, and are likely to be major contributors to the chronic pain that is the most common symptom of the condition.  However, for the purpose of this announcement, osteoarthritis is distinguished from other joint diseases, such as rheumatoid arthritis, in which inflammation arising from autoimmunity is the primary cause of tissue damage. The root causes of joint degeneration in osteoarthritis remain unclear. Research efforts in the past have focused primarily on the more advanced stages of osteoarthritis, but relatively little is understood about the initial changes triggering disease etiology and early progression.  This FOA is intended to encourage and accelerate the characterization of new or underutilized models and the testing of hypotheses that will lead to an improved understanding of the mechanisms mediating osteoarthritic progression."

 To Register

Notice of Intent to Publish a Funding Opportunity Announcement (FOA) on Multidisciplinary Studies in HIV/AIDS and Aging (R03)
Notice Number: NOT-AG-12-004
"The National Institute on Aging (NIA) announces a trans-NIH Funding Opportunity Announcement (FOA) on Multidisciplinary Studies in HIV/AIDS and Aging. This FOA will encourage applications proposing to study HIV infection, HIV-associated conditions, HIV treatment, or biobehavioral or social factors associated with HIV/AIDS in the context of aging and/or in older adults. The research areas encouraged in this FOA are based, in part, on the recommendations of the Working Group on HIV and Aging convened by the NIH Office of AIDS Research. These areas include, but are not limited, to the following:
*    Cellular and molecular mechanisms of HIV in aging
*    Biomarkers or clinical indices of HIV-associated pathology
*    HIV-Associated Non-AIDS (HANA) conditions / Co-morbidities
*    HIV-Associated Neurocognitive Disorders (HAND)
*    Intervention studies (prevention or treatment)
*    Frailty/Vulnerability
*    Social, behavioral, and mental health studies
The FOA is expected to be published in Spring 2012 with non-standard receipt dates beginning in Summer 2012. Multiple other NIH Institutes and Centers are expected to participate."

Please direct all inquiries to
:
Basil Eldadah, MD, PhD
Division of Geriatrics and Clinical Gerontology
National Institute on Aging
7201 Wisconsin Ave, Suite 3C307
Bethesda, MD 20892
Phone: 301-496-6761
Email:[email protected]

Network and Infrastructure Support for Development of Interdisciplinary Aging Research (R24)

Program Announcement (PA) Number: PA-12-064
"The purpose of this FOA is to provide network and infrastructure support to foster development of novel interdisciplinary research approaches on important topics in aging research. This FOA will use the NIH Resource-Related Research Project (R24) mechanism to facilitate research networks that will advance specific scientific goals through activities such as meetings, conferences, small scale pilots, short term training opportunities, and visiting scholar programs, and dissemination activities to encourage growth and development in these interdisciplinary areas."

 To Register

National Science Foundation funding grant "General & Age-Related Disabilities Engineering (GARDE)"
"The General & Age Related Disabilities Engineering (GARDE) program supports research that will lead to the development of new technologies, devices, or software for persons with disabilities.  Research may be supported that is directed to the characterization, restoration, and/or substitution of human functional ability or cognition, or to the interaction of persons with disabilities and their environment.  Areas of particular recent interest are disability-related research in neuroscience/neuroengineering and rehabilitation robotics.  Emphasis is placed on significant advancement of fundamental engineering and scientific knowledge and not on incremental improvements.  Proposals should advance discovery or innovation beyond the frontiers of current knowledge in disability-related research.  Applicants are encouraged to contact the Program Director Ted Conway at [email protected], or call (703) 292-7091, prior to submitting a proposal."


 To Register 

 

The New Investigator Awards in Alzheimer's Disease
"Funded by The Rosalinde and Arthur Gilbert Foundation and The Diane and Guilford Glazer Foundation, the major goal of this partnership program is to support important research in areas in which more scientific investigation is needed to improve the prevention, diagnosis, and treatment of Alzheimer's disease. The program will also serve to encourage junior investigators in the United States and Israel to pursue research and academic careers in the neurosciences, and Alzheimer's disease in particular. Projects in basic and translational research related to Alzheimer's disease (AD) that are clinically relevant, will be considered. Projects that focus on healthy brain aging are also considered. For one of the awards, priority may be given to an investigator with a research interest related to healthy brain aging. Areas of research could for example include learning and memory, nutrition, exercise, cardiovascular risk factors, as they relate to the brain and the aging process. The applicant must be an independent investigator with assigned independent space as assigned by the departmental chair or equivalent official, and must be within the first ten years of receiving a doctoral degree by July 1, 2011. Exceptions to the ten year rule may be requested for unusual circumstances by emailing an NIH-style bio-sketch to AFAR at [email protected] .The proposed research must be conducted at any type of not-for-profit setting in the United States or Israel."

  

To Register 

 

 

 


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The Translational Research Institute on Pain in Later Life (TRIPLL) is an NIA funded Edward R. Roybal center with a focus on persistent pain due to both cancer and non-cancer related causes. TRIPLL is a collaboration between investigators at Weill Cornell Medical College, Cornell-Ithaca, Columbia University's Mailman School of Public Health, Hospital for Special Surgery, Memorial Sloan Kettering Cancer Center, Visiting Nurse Service of New York and Council of Senior Centers & Service of NYC, Inc.

 

For more information on TRIPLL please contact Marcus Warmington at [email protected]