Dear Friends,
What a remarkable year you helped create! 2013 has seen so many encouraging developments - in laboratories and clinics - that will accelerate the development of better treatments and a cure for ACC.
And it is all thanks to your ongoing support!
Here is a small sampling of some key milestones:
- Encouraging clinical trials - The results of 4 clinical trials for ACC patients were announced in June. These studies had more patients, more rapid accrual and more promising results than we have seen in past clinical trials.
- Pivotal DNA sequencing studies - Two studies from researchers at the Sanger Institute, MD Anderson and Memorial Sloan-Kettering were published in the spring. We learned that ACC tumors have "quiet genomes" with few alterations, hopefully meaning that the tumors will be simpler to target.
- Creating a roadmap - ACCRF published its initial Research Agenda in 2006 to help guide researchers to the most fruitful projects. Thankfully, many of the initial objectives have been accomplished, necessitating a refreshed document. ACCRF's Scientific Advisory Board and network of researchers all contributed in 2013 to drafting The Landscape of ACC Research as a new roadmap.
- Ground-breaking scientific meeting - ACCRF convened the first-ever conference that brought together ACC researchers and experts on MYB, the gene that appears to be a cause of most ACC tumors. ACCRF already has funded collaborations that grew out of the meeting to learn how MYB works and to discover more promising drugs.
The generosity of donors like you has made this possible!
Looking forward, 2014 should be filled with excitement as well. Brilliant researchers with cutting-edge technologies are hard at work searching for the Achilles' heel of ACC. In the coming year, we may reasonably expect to learn of new molecular targets, new medicines and new clinical trials that can improve the outlook for ACC patients.
Of course, amidst all the promise, the year also has been very painful for many in the ACC community. Family members and friends continue to undergo difficult treatments and too many patients have been taken from us by this horrible disease
As a reminder, Our Circle of Sustenance donors have committed to covering all administrative expenses, ensuring that 100% of your donation will fund ACC research projects.
We have a great plan of action and a great community to carry it out. We look forward to walking side by side with you on our journey of hope!
Warm wishes for the holiday season,
The ACCRF Board of Directors
Jeff Kaufman, Executive Director Marnie Kaufman
Tom DiLenge Douglas Meyer
Kara Gelb Ralph Mollis
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