Upcoming HSCI Events
Harvard University
Friday, Oct. 9
11:00 AM - 12:00 PM 

The Skin Disease Program will formally kick-off with a day-longsymposium designed to highlight skin stem cell research as it relates to regenerative medicine, skin cancer biology, cutaneous aging, and disease prevention. 
Harvard Medical School
Thursday, Nov. 12
8:00 AM - 5:00 PM
Funding Opportunities
to support newly independent faculty, provide the opportunity to demonstrate creativity, and assist in the transition to other sources of research funding. Research projects must be relevant to child health. 
Application deadline: 
October 2, 2015

invites researchers to submit nominations for three awards: the McEwen Award for Innovation, the ISSCR Dr. Susan Lim Award for Outstanding Young Investigator, and the ISSCR Tobias Award Lecture
Nomination deadline: 
October 15, 2015
Job Opportunities
Postdoctoral and professional positions are available in the following HSCI and HSCI-affiliated labs:
  Karp Lab at Brigham and Women's Hospital
Merkle Lab at University of Cambridge, UK  
Rubin Lab at Harvard University 
Rubin Lab at Harvard University
Shah Lab at Massachusetts General Hospital and Harvard Medical School 
Turka Lab at Massachusetts General Hospital
Karmacharya Lab at Massachusetts General Hospital
People News
  Robert Fuhlbrigge, MD, PhD, from Brigham and Women's Hospital, joins HSCI as Affiliated Faculty.  

Jonathan Hoggatt, PhD, from Massachusetts General Hospital, joins HSCI's Principal Faculty. 

Matthew Ramsey, PhD, from Brigham and Women's Hospital, joins HSCI as Affiliated Faculty. 

Vijay Sankaran, MD, PhD, from Boston Children's Hopsital, joins HSCI's Principal Faculty. 

Tobias Schatton, PharmD, PhD, from Brigham and Women's Hospital, joins HSCI as Affiliated Faculty. 

Jeff Karp, PhD, from Brigham and Women's Hospital, is named one of Boston Business Journal's 40 Under 40

If you would like to share your achievements, awards, or research with the HSCI community, please email hannah_robbins@harvard.edu
Making SMA Motor Neurons 
Lee Rubin, PhD, uses a new method to study motor neurons derived from SMA patients. 
A team of researchers, led by HSCI Executive Committee member Lee Rubin, generated neurons derived from SMA patients in order to determine why the disease causes motor neurons to die selectively. Using a method of intracellular cell labeling developed by Doug Melton's lab, the team was able to separate motor neurons from the other generated neurons and compare the motor neurons of SMA patients to those from healthy individuals. Read the  full story here.  
Research and Reviews
  • Cohen Lab: Two-photo florescence lifetime imagining measures absolute membrane voltage (Biophysical Journal paper)  
  • Meissner Lab: Transcript profiling can be used to track the healing progression of traumatic lower-limb musculoskeletal injuries. (Nature Scientific Reports paper)
  • Rajagopal Lab: A call to use disease- and patient-specific iPSCs to establish human model systems for cystic fibrosis. (Pediatric Pulmonology article) 
  • Shah, Daley, Orkin, and Zon labs: Hematopoietic stem cells emerge, migrate, engraft, and differentiate in the absence of cdh5 expression. Cdh5 is a marker of hemogenic endothelium in the aorta-gonad-mesonephros. (Blood paper)
  • Weissleder Lab: BODIPY TMR-X labeled exendin-4-like neopeptide is an ideal reagent for flow sorting and analysis of live mouse B-cells. (Nature Scientific Reports paper)
  • Woolf Lab: Motor recovery plateaus even after the reformation of the once denervated neuromuscular junction, challenging the hypothesis that lack of motor recovery after an injury is due to regenerative failure. (European Journal of Neuroscience paper)
HSCI Internship Program Honors the Memory of a Former Intern

Nada Anzak "was young, full of ambition, and had a wonderful sense of adventure," recalls Willy Lensch, PhD, co-director of The Harvard Stem Cell Institute Internship Program (HIP)."She was a serious scientist, an exceptional friend and colleague in the lab, and a very accomplished student." During her summer at HSCI, in 2012, Anzak, then a medical student at King's College London, even won an award from the Royal College of Ophthalmologists for her work in the HSCI program.
Tragically, Anzak died in 2013 at the age of 22 of diffuse large B-cell lymphoma - an aggressive form of blood cancer. This summer, HSCI honored her memory with the awarding of the Nada Anzak Memorial Award to HIP intern May Barakat, a Harvard undergraduate, at the conclusion of the 2015 internship program symposium. 

Read more about Nada Anzak, May Barakat, and the summer internship program here