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Media Mentions
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11/14/13
Slate.comAnimation depicts Daley Lab finding that reactivating a dormant gene enhances mice's healing abilities. 11/6/13 Bioscience TechnologyProfile of heterochronic parabiosis work done by Amy Wagers, PhD.
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Recent HSCI Papers
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11/3/13 Nature NeuroscienceThe mouse C9ORF72 ortholog is enriched in neurons known to degenerate in ALS and FTD 10/11/13 ScienceWhat are mini-brains? |
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Human Muscle Stem Cell Therapy Gets Help from Zebrafish
Len Zon, MD, Amy Wagers, PhD, and Ronald Kahn, MD, collaborate to find chemicals that spur muscle development across species.
 Harvard Stem Cell Scientists have discovered that the same chemicals that stimulate muscle development in zebrafish can also be used to differentiate human stem cells into muscle cells in the laboratory, an historically challenging task that, now overcome, makes muscle cell therapy a more realistic clinical possibility. Continue reading.
Read the paper in Cell. |
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New Model for Kidney Repair, May Not Require Stem Cells
Ben Humphreys, MD, PhD, finds evidence of dedifferentiation.
 HSCI researchers have a new model for how the kidney repairs itself, a model that adds to a growing body of evidence that mature cells are far more plastic than had previously been imagined. Continue reading.
Read the paper in PNAS and a review of kidney injury and stem cells in Curr Opin Nephrol Hypertens. |
Focus on Rhabdomyosarcoma
Three scientists discuss how they study cancer in muscle stem cells.
In this feature, one senior investigator (Len Zon, MD), one junior investigator (Dave Langenau, PhD), and one postdoctoral researcher (Simone Hettmer, MD)--all members of the HSCI--share recent findings that could lead to safer treatments for young cancer patients. Learn more.
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Research Updates
- David Scadden, MD, finds bone drug that kills resistant leukemia stem cells by making home unlivable.
- George Daley, MD, PhD, finds that Lin28 promotes repair of hair, cartilage, bone, and soft tissues.
- Joseph Bonventre, MD, PhD, uses patient stem cells to gain insight into polycystic kidney disease; also links kidney injury molecule-1 to chronic kidney disease.
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