February, 2014


The Importance of Being Industrious: 
Partnering for real world impact


We've all heard the phrase, "bench to bedside," and I think we can all agree it's a reality we would like to make happen as often as possible. We are also aware that this process can typically be long and arduous. At MCIRCC, we are interested in understanding the mechanics needed to accelerate the process of bringing new innovations from the bench to bedside and continuously sharing and building that knowledge among science teams across U-M. We want to continuously be in knowledge-gaining mode.

Kevin Ward, MD, UM-Emergency Medicine


Creating strong and dynamic industry partnerships is key to achieving this goal. Partnerships with industry not only help get innovation we develop internally out to the market; they also help industry partners innovate their current or future product lines. It's as much about 'how can we help you innovate your next generation of products focused on critical care or injury?'


There is a potential opportunity to do co-product development on a basis that accelerates new discovery but is done by simultaneously taking those discoveries and putting them in a product pipeline that gets them out to market. The potential to shave years off of product development and implementation in the clinic would be an amazing thing.


We have the power to help give industry the edge that it needs to develop products on a regular schedule, which ultimately benefits patients...and this is always our main focus. 


IMPACT: Grand, Indeed.

The MCIRCC Critical Care Grand Challenge: Sepsis


The MCIRCC Critical Care Grand Challenge is indeed grand in its scope and aspiration. Nearly 50 members comprised of scientific innovators from across the U-M campus attended the first annual event on January 24 and 25, which zeroed in on sepsis and the complexities around treating it across the critical care spectrum.


U-M Pediatric Intensivist Timothy Cornell discusses the challenges in treating septic patients and his wish list to improve outcomes.

Day 1 of the program examined the complex science, value and challenges in solving sepsis; potential models for new therapeutics, diagnostics, devices or digital health solutions to support the septic patient and health care provider were also presented.


Day 2 introduced our members to internal U-M resources and entrepreneurial fundamentals to support the development of solutions suitable for future commercialization. By helping our members define and understand their potential customers, we can focus their research beyond the idea stage for real-world impact. Developing both a scientific and business roadmap are key to this process and MCIRCC is key in helping teams with this step.

The two-day program closed on a high note, with the release of the Grand Challenge Funding Opportunity to support high-impact proposals up to $100,000 per project for milestone driven research to take place over the next 18 months. Taking a unique "team science" approach, each Proposal must have a joint PI from the U-M Medical School and College of Engineering. 


Deadline for funding consideration: February 21, 2014


For complete information on the Grand Challenge RFP, or to submit your Team's Stage 1 Proposal, please visit the Competition Space website. We also prepared a FAQ for your reference.


The MCIRCC Team is happy to help along the way; e-mail Janene Centurione at jrcentu@umich.edu.


If you missed the Grand Challenge event, want to review what you learned, or spread the knowledge to others:


Click here to download the presentation sessions (password: MCIRCC).


Read our 8-page Sepsis Brief: a comprehensive summary of the challenges, complexity, and far-reaching implications of the disease as discussed at the Grand Challenge event.

CONNECT: Innovation Mob - Health IT

Interested in Health IT?  Have a great Health IT idea but need help getting started?


Then you will want to attend the Health IT Innovation Mob, a one-day hands-on accelerator designed to:

  • Connect like minded people interested in making an impact on the health and well-being of others.
  • Teach and apply cutting edge concepts and tools to implement your idea.
  • Provide expert mentoring from people who have launched successful Health IT ventures.
  • Examine Health IT issues such as FDA regulations, HIPPA, IRB, Interoperability and much more.

February 22, 2014

8:00 am - 4:00 pm
School of Public Heath, Room 3755


Click here for more information and to RSVP


The Innovation Mob is a partnership between the U-M Center for Entrepreneurship, College of Engineering, School of Public Health, School of Information, Medical School and Office of Technology Transfer.


Innovation Underground
FREE Networking Event

March 6, 2014
5:00 pm - 7:00 pm

Mash Bar (under Blue Tractor)
211 East Washington Street

Join your MCIRCC colleagues, leading scientists, entrepreneurs, and industry partners, for a night of networking and mingling. Second in a series of free informal get-togethers, we'll raise a glass, chat, share ideas, and lay the groundwork for meaningful collaborations that may lead to new and novel ways to change the face of critical care.

Click here to register for this free event and bring along your research team.