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Dear Doctor, 
Welcome to the latest edition of BioSpeak. This month we are focusing on our range of Multi-Neurotrophin Rapid™ Screening ELISA Kits - for the detection of multiple Neurotrophins in your samples at one Go! To find out more click here


Multi-Neurotrophin standard curve

Our Multi-Neurotrophin Rapid™ Screening ELISA Kits are excellent for a quick screen of precious samples. Our kits offer detection of NGF, BDNF, NT3 and NT4/5 in less than 4hrs without the loss of sensitivity of our full-size kits.



We offer 3 Multi-Neurotrophin Rapid™ ELISA Kits for Human (BEK-2227), Mouse (BEK-2231) and Rat (BEK-2232) samples.



Biosensis is offering a discount of 20% for your first purchase of a Multi-Neurotrophin Rapid™ Screening ELISA Kit.  

 
Mention code BIOSENSISNOV16 when you email or call in your order. Offer valid until November 30th, 2016. For direct purchases only.

To enquire please email sales@biosensis.com   
 

Multi-Neurotrophin Rapid Screening ELISAs
Latest Publication
Are You Missing Important Data?
Biosensis' Fast and Sensitive Rapid ELISA Kits
Left Figure

Standard curves of our Human

Multi-Neurotrophin Rapid™ Screening ELISA Kit (Catalog No# BEK-2227).


Latest Publication 
Biosensis' Human Multi-Neurotrophin Rapid™ Screening ELISA Kit (BEK-2227) was successfully used in a most recent (2016) publication by Susan Louise Lindsay and co-workers:
  • Lindsay SL, et al, (2016). "Comparative miRNA-Based Fingerprinting Reveals Biological Differences in Human Olfactory Mucosa- and Bone-Marrow-Derived Mesenchymal Stromal Cells." Stem Cell Reports, 10;6(5):729-42. PMID: 27117785 PMCID: PMC4940454.
In this work Lindsay and her colleagues reported results obtained with our BEK-2227 ELISA that demonstrated detectable and reproducible differences in secreted neurotrophin expression between nestin-positive human mesenchymal stromal cells derived from the olfactory mucosa (OM-MSCs) and bone-marrow-derived MSCs (BM-MSCs) using conditioned media as a substrate. Within one sample the authors reported detectable differences in NT4/5, NGF and BDNF simultaneously following our prepared protocols. This work demonstrates the effectiveness, efficiency and cost savings gained by using Biosensis' Multi-Neurotrophin Rapid™ ELISA's for such research and we look forward to more similar publications very soon.


Application: ELISA. Species: Human, MSC-conditioned medium/cell supernatant. 



Are You Missing Important Data? 

If you are quantifying BDNF or NGF, then you may be missing important data!  

Biosensis' Multi-Neurotrophin Rapid™ Screening kits allows quantification of multiple neurotrophins with the precision, accuracy and ease you have enjoyed when using our full-size Rapid™ ELISA kits. 

 

Neurotrophins do not act independently. Many publications have described the coordinated actions of 2 or more neurotrophins, which is best described in development, however this is increasingly being recognized in adults. Below are a number of selected references that further address this issue:



Huang and Krimm, 2014. "BDNF and NT4 play interchangeable roles in gustatory development."



Hoyng et al, 2014. "A comparative morphological, electrophysiological and functional analysis of axon regeneration through peripheral nerve autografts genetically modified to overexpress BDNF, CNTF, GDNF, NGF, NT3 or VEGF."



Esmaeili et al, 2014. "Messenger RNA Expression Patterns of Neurotrophins during Transdifferentiation of Stem Cells from Human-Exfoliated Deciduous Teeth into Neural-like Cells."



Bothwell, 2014. "NGF, BDNF, NT3 and NT4."



Biosensis' Multi-Neurotrophin Rapid™ Screening ELISA kits are re-formulated versions of our full-size kits. These kits allow the quantitative testing of 16 samples for multiple neurotrophins simultaneously. The kits are particularly useful for screening cell cultures, tissue extracts and serum samples prior to completing a large-scale study to ensure that you are not missing important data.



Biosensis' Fast and Sensitive Rapid™ ELISA Kits
Biosensis' Fast and Sensitive Rapid™ ELISA kits allows you to get your results by lunch time!



We also offer a full-size Rapid™ ELISA Kit for each Neurotrophin below:
  • NGF Rapid™ ELISA Kit: Human (BEK-2212), Mouse (BEK-2213) and Rat (BEK-2214)
  • Mature BDNF Rapid™ ELISA Kit: Human, Mouse, Rat (BEK-2211)
  • Neurotrophin 3 (NT3) Rapid™ ELISA Kit: Human, Rat and Mouse (BEK-2221)
  • Neurotrophin 4/5 (NT4/5) Rapid™ ELISA Kit: Human, Mouse, Rat and Monkey (BEK-2218)


Biosensis is committed to providing the highest-quality products to the research community.

If you would like to know more about our Multi-Neurotrophin Rapid™ Screening ELISA Kits you can contact one of our experienced researchers at biospeak@biosensis.com.



Plus stop by our booth #636 at this year's SFN to say hello.



Until next time, good luck with your research.



Sincerely,

The Biosensis Team



Contact Information

Biosensis Pty Ltd

Address: 40-46 West Thebarton Road

Thebarton SA 5031 Australia

Email: info@biosensis.com

Phone: +61 8 8352 7711 - In the United States, call us in California toll free on 1800 605-5127

Web: www.biosensis.com





Biosensis Pty Ltd | 39 Winwood Street | Thebarton | South Australia | 5031 | Australia