Blood test to predict Alzheimer's disease
Scientists are getting closer to developing a blood test for Alzheimer's disease according to new research published this week.

British scientists monitored 220 patients with mild cognitive impairments and identified 10 proteins that were present in the blood of 87 per cent of the study participants who went on to develop Alzheimer's within a year.
A blood test could be developed to detect the proteins in the blood, potentially allowing screening for the brain-wasting disease and earlier treatment with drugs for those testing positive.
"Many of our drug trials fail because by the time patients are given the drugs, the brain has already been too severely affected," said Oxford University neuroscience professor Simon Lovestone, who led the study at King's College London.
"A simple blood test could help us identify patients at a much earlier stage to take part in new trials and hopefully develop treatments which could prevent the progression of the disease.
"The next step will be to validate our findings in further sample sets."
Around 35 million people worldwide suffer from Alzheimer's, 50,000 in New Zealand. The fatal disease had an estimated global social cost in 2010 of US$604 billion. The research was published in the journal Alzheimer's & Dementia.
Alzheimer's New Zealand welcomed the study findings:
"Receiving a diagnosis allows people affected by dementia to access services and support from local Alzheimers organisations and gives them the opportunity to plan for their future. Diagnostic tools such as this would be very helpful in detecting dementia in its early stages, and may add to the ability to do further research into prevention of dementia," a statement read.
"However it is early days for this study and further trials are required with a diverse range of people before its effectiveness can be determined."
Our colleagues at the UK SMC gathered reaction from experts:
Dr James Pickett, Head of Research, Alzheimer's Society, said:
"Finding a way to detect dementia before symptoms develop would revolutionise research into the condition. Most of the blood proteins identified here are not new to the dementia community, but this study has brought them together into a protein set that seems to predict disease severity. Although it needs to be validated in a larger group of people, their modelling work shows a set of 10 proteins can predict which people with mild cognitive impairments will progress to developing dementia.
Read the commentary in full here.
Read Diedrie Mussen's report on the research findings in the Dominion Post
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