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Unknown Slide Review
Literature Update
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Consultation Service


  September 2009

Greetings!

Thank you for taking the time to review our newsletter and update yourself in the latest from dermatopathology.

Had a great summer and hope all of you did as well.

Thank you.
Paul K. Shitabata, M.D.
The Dermatopathology Institute
Unknown Slide Reviews
Melanoma, Desmoplastic Unknown Slide Review Part 31

Test your diagnostic acumen with this review of interesting cases from this past week's signout.

What is this pleomorphic tumor composed of both spindled and epithelioid cells that is S100 positive but Melan-A and HMB-45 negative?
 
Unknown Slide Reviews

Dermatopathology Slide Atlas










Diagnostic Pearls from the Dermatopathology Literature
Desmoplastic Melanoma

Subclassification of Desmoplastic Melanoma: pure and mixed variants have significantly different capacities for lymph node metastases. J Cutan Pathol 2009;36:425-432.

This is an excellent article that provides compelling evidence to histologically separate pure and mixed desmoplastic melanomas since pure variants nearly never metastasize to regional lymph nodes while melanomas with a mixed pure desmoplastic and conventional melanoma histopathology have a significantly higher percentage of lymph node metastases.
If you would like one of our dermatopathologists to give a talk to your office or facility, please contact us directly.


Thank you!
 

Paul K. Shitabata, M.D.
President and Medical Director
Dermatopathology Institute
Director of Dermatopathology, Harbor-UCLA Dermatology