University of Colorado
Technology Transfer Office
Monthly Newsletter
May 2009 - Vol 5, Issue 11
TTO Logo & CU Logo
What's Inside
Spotlight
CU Technology in the News
People
Upcoming Events
Innovation in the News
External Resources
Parting Quote
Links
 
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Spotlight On:

CU-Boulder Technology of the Month:

8045B - Sustained-release drug delivery composition including amorphous polymer


UC Denver Technology of the Month:

CU1527H - Novel therapeutics for prostate cancer bone metastases


Recently at TTO

GlobeImmune and Celgene Corporation Announce Strategic Global Oncology Alliance
In May, CU licensee GlobeImmune, Inc. and Celgene Corporation announced a worldwide strategic collaboration focused on the discovery, development and commercialization of multiple product candidates based on powerful, targeted molecular immunotherapy for the treatment of cancer. Under the terms of the agreement, GlobeImmune will receive a $40 million upfront payment from Celgene, which includes an equity investment in GlobeImmune.

InDevR Licenses CU FluChip Technology to Combat Deadly Swine Flu Virus
InDevR Inc., a small biotech company in Boulder, announced in late April that they have licensed the FluChip technology from the University of Colorado. The FluChip was invented by a joint team of scientists at the University of Colorado and the Centers for Disease Control and Prevention, in an NIH-sponsored effort led by Professor Kathy Rowlen. Rowlen, now the CEO of InDevR, said that InDevR has arranged to test genetic material from the recent swine H1N1 virus on the MChip as well as other versions of the FluChip which are under development.

BlueSun, Inc. Commercializing CU Trauma Recovery Program
Colorado Springs-based BlueSun, Inc. has finalized an agreement with the University of Colorado to license the Journey to Disaster Recovery™ and Journey to Trauma Recovery™ programs developed by Dr. Charles Benight and his collaborators at the Trauma, Health, and Hazards Center and the Computer Science Department at the University of Colorado at Colorado Springs. The Journey to Recovery™ websites are ideal for disaster recovery situations where traumatized individuals have little access to recovery assistance due to environmental logistics - for example, when there are few mental health providers available - and in situations where public movement is restricted like a pandemic influenza outbreak, or when people fear being labeled because they are accessing mental health services.

CU Graduate Programs Remain Among the Nation's Best
Twenty-eight academic programs across the university's campuses in Boulder, Colorado Springs and Denver, including the Anschutz Medical Campus in Aurora, remain nationally ranked in the 2010 U.S. News & World Report graduate school rankings released in late April. The magazine ranked three graduate programs at the UC Denver School of Medicine among the top 10 in the nation, including family medicine at third, primary care at fourth, and pediatrics at eighth. CU-Boulder's atomic, molecular and optical physics program is top-ranked nationally, quantum physics program is fourth, and plasma physics is ranked 10th nationally. CU-Boulder's Deming Center for Entrepreneurship at the Leeds School of Business was also ranked in the top 20 business school programs.

Job Corner

TTO Seeks Chemistry/Chemical Engineering Licensing Associate

TTO is seeking a Chemistry or Chemical Engineering Licensing Associate for its Boulder office. The Licensinge Associate identifies, solicits, and evaluates invention disclosures for patent and market potential; markets technologies to commercial partners; and tracks and develops a portfolio of associated intellectual property. Please review full requirements and apply online at www.jobsatcu.com (posting #807021).

CU Technology and Licensee Companies in the News

Across America Financial Services Completes Acquisition of APRO Bio Pharmaceutical Corporation
In April, Across America Financial Services, Inc. completed the acquisition of APRO Bio Pharmaceutical Corporation, a developmental stage biopharmaceutical company. As the licensee of a number of issued and pending patents from the University of Colorado, Apro has been advancing several broad-spectrum therapeutics targeting bacterial and viral diseases, biohazards, and transplant rejection. The combined company will be known as "Omni Bio Pharmaceutical, Inc."

GlobeImmune Drug has Positive Hep-C Trial
Phase 2 clinical trial data show that patients treated with GI-5005, GlobeImmune's targeted molecular immunogen (Tarmogen®) for the treatment of hepatitis C virus infection, had 94 percent early virologic response rate in treatment-naļve patients. The study compared GI-5005 plus standard of care (SOC)-pegylated interferon and ribavirin-versus SOC alone in patients with chronic genotype 1 hepatitis C infection.(See also: GlobeImmune Starts Cancer Drug Trial.)

Deerfield Buyout of Nitromed Finalized; Archemix to Receive Termination Payment
Healthcare investment company Deerfield Management has closed its acquisition of the Lexington-based based drug maker NitroMed Inc. The acquisition superseded two prior deals NitroMed had ongoing, including a merger agreement with CU licensee Archemix Corp.. To terminate this prior deal, NitroMed agreed to pay $1.5M to Archemix.

RealD Introduces World's First Mobile, Single-Projector 3D Solution
RealD, the world's leading 3D technology company, is introducing the RealD LP™ (Linear Polarizing Z Screen) to bring the power of 3D to the small screen. RealD LP brings the vibrancy of high-quality 3D to smaller venues such as conference rooms, R&D centers, museum exhibits, mobile education centers, virtual rides and other entertainment attractions.

CU Researchers Shrink Nano Circuitry
A research team headed by CU-Boulder Assistant Professor Robert McLeod (electrical, computer and energy engineering) has developed a method of shrinking the size of circuitry used in nanotechnology devices such as computer chips and solar cells. The method offers potential new approaches in the search for ways to shrink transistor circuitry, a process that drives the global electronic market that is pursuing smaller, more powerful microchips. (See also: Novel CU-Boulder Technique Shrinks Size of Nanotechnology Circuitry.)

CU-Boulder Researchers Develop New 3-D Platform for Growing Cells
"There's a lot of interest in developing better cell culture platforms," said April Kloxin, a postdoctoral research associate with the Howard Hughes Medical Institute and the department of chemical and biological engineering at CU-Boulder. "There has been a lot of 2-D work, but research has shown that it's important that it happen in 3-D, in a situation that mimics the way it happens in the body." To solve that problem Kloxin and chemical and biological engineering Distinguished Professor Kristi Anseth have developed a new cell culture platform that allows for more realistic experiments. The team's paper on the new substance was published this month in the journal Science (read full article, or click here and here for summaries CU 3D hydrogel technology available for licensing).

People

CU President Names Phil DiStefano Boulder Chancellor
In early May, CU President Bruce D. Benson named Phil DiStefano the 11th chancellor of the CU-Boulder campus. DiStefano has served CU for 35 years as an education professor, associate dean, dean, vice chancellor, provost, and as interim chancellor during pivotal periods in the university's history. (See also: Stein Sture Named Interim Provost at CU.)

Podcast: Dr. John Carroll & Dr. James Chen, UC Denver Inventors of the Year
Drs. Carroll and Chen have collaborated for nearly two decades to develop various computer-assisted utilities to facilitate diagnostic and therapeutic procedures in cardiac catheterization laboratories. W3W3 internet radio talked with these collaborators on a number of topics including funding and its challenges during these economic times.

Podcast: Dr. Heide Ford & Dr. Rui Zhao, UC Denver New Inventors of the Year
"That sort of cancer therapy is badly needed - many of the therapies available today actually target the normal cells too. That's why people get terrible side effects. So we're hoping to develop drugs that will eliminate or at least reduce the side effects significantly while inhibiting the cancer." Heide Ford and Rui Zhao, UC Denver New Inventors of the Year for 2008, discussed their current research collaboration, and offered advice for professors and researchers.

CU-Boulder's Deborah Jin Keeps It Cool with Quantum Mechanics
The 2004 Scientific American 50 researcher of the year continues to tweak matter at the edge of known physics to reveal strange and potentially useful properties.

UC Denver Professor Shares Largest U.S. Award for Medicine
University of Colorado Denver School of Medicine professor Charles A. Dinarello, MD, is one of the awardees of the $500,000 Albany Medical Center Prize in Medicine and Biomedical Research, recognizing Dinarello for isolating, purifying and leading the cloning effort of the body's own molecule that causes fever and inflammation associated with some forms of cancer, rheumatoid arthritis and other chronic inflammatory diseases.

CU Law Professor Phil Weiser, Founder of Silicon Flatirons, Appointed to Justice Department
In late April it was announced that CU Law School Professor Phillip Weiser, Executive Director of the Silicon Flatirons Center for Law, Technology and Entrepreneurship and Associate Dean for Research, has accepted an appointment as Deputy Assistant Attorney General for international, policy, and appellate matters at Justice Department's Antitrust Division.

Do you know of a recent award, new position or transition of interest to the CU tech community? Please send information to TTOnews@cu.edu.
Upcoming Events

Graduate Nanotechnology Symposium

May 26, University of Denver

This free symposium hosted by the DU Center for Nanoscale Science and Engineering will feature 25 speakers covering a variety of topics - info and registration online.

 

Application Deadline: Rocky Mountain Clean Tech Open

May 30

The Rocky Mountain Clean Tech Open (RMCTO) is both a business plan competition for early stage clean tech startups, and a thriving community of clean tech entrepreneurship. The competition enables entrepreneurs to turn clean technology ideas into thriving businesses. Winners receive "Startup-in-a-Box" packages of cash and services up to $100,000 and donated by high-profile sponsors.

 

Boulder/Denver New Technology Meetup Group
June 2, CU- Boulder
This ongoing event provides a forum for technologists and entrepreneurs to showcase the new (especially web-based) technology developing in Boulder/Denver tech community. Five companies have five minutes each to demonstrate their new technology, followed by five minutes for Q&A from the audience.

 

Workshop: Using Devices in Clinical Trials

June 8-9, Anschtuz Medical Campus, Aurora

The Food and Drug Administration will be at the UC Denver Anschutz Medical Campus to discuss rules, regulations, and responsibilities when using devices in clinical trials. Presented by the Colorado Colorado Clinical and Translational Sciences Institute (CCTSI).

 

CSIA 2009 Apex Awards

June 9, Infinity Park, Glendale

Join hundreds of Colorado's biggest and brightest at the 9th Annual Apex Awards, recognizing the achievements of amazing technology companies and professionals here in Colorado.

 

Bard Center 8th Annual Business Plan Competition

June 10, Grand Hyatt, Denver

The Bard Center Business Plan Competition-the premier academic business plan competition in Colorado-seeks to promote the development of high-caliber business plans, recognize the most outstanding plans with cash and in-kind awards from area businesses, and encourage the creation of new businesses.

 

Colorado Green Tech Meetup

June 11, CU-Boulder

An ongoing event to support eco-entrepreneurs and others people involved and/or interested in green tech: energy generation, transportation, construction, and efficiency technologies. Businesses and researchers present new technologies, and attendees may announce business news, job openings, fundings, etc.

 

Nano Renewable Energy Summit

June 22-23, University of Denver

The Nano Renewable Energy Summit is a gathering of world-renowned experts at the intersection of solar energy and nanotechnology, with a specific focus on the business, commercialization, and economic development potential of emerging technologies in the renewable energy and sustainability sectors.

 

RETool: Renewable Energy Technologies Workshop

July 9-11, CU-Boulder

This two-day training workshop led by CU-Boulder faculty will tell you what you need to know about renewables - where are the opportunities, what are the current key challenges, and how to break into the renewables industry.


To have your event featured here, please send an email to TTOnews@cu.edu.
Innovation in the News

Obama Announces Major Investments in Research and Education
In a late-April speech to members of the National Academy of Sciences, President Barack Obama announced new initiatives and investments in scientific research, innovation, and education. Calling science "more essential for our prosperity, our security, our health, and our environment than it has ever been," Obama said he is going to make major investments - 3% of the gross domestic product - in research and innovation (see quote below). For more information, view the webcast or the White House fact sheet.

Governor's Renewable Energy Program Makes Strides
Governor Ritter's Renewable Energy Technology Program is starting to produce results, creating clean-tech companies here in Colorado that are already making a global impact on alternative energy development and controlling climate change. TheEnergy Program at the Boulder Innovation Center (BIC) has assisted dozens of promising start-up companies over the last year, including CU-based ION Engineering.

Boulder's Kyle Lefkoff on Tech, Biotech VC Investments
Venture capital funding is down nearly 50 percent nationwide during the first quarter of 2009, according to a report released last week. Colorado recorded its lowest level of activity since the fourth quarter of 2004. Kyle Lefkoff has been in the venture capital industry for nearly 25 years and was a founder of Boulder Ventures. Lefkoff's firm specializes in equity investments to technology and life sciences. The Daily Camera talked briefly with Lefkoff about the state of the market and what is piquing his firm's interest.

Brad Feld, Foundry Group Co-founder, on Venture Capital and Entrepreneurship
Brad Feld has been an entrepreneur and an investor in early-stage companies for more than 20 years. Feld, who publishes a popular blog called "Feld Thoughts" at www.feld.com, also is extremely active in the local and national technology and innovation scenes. Feld, who co-founded the Boulder-based Foundry Group investment firm, also was one of the co-founders of TechStars, a mentor-based summer program for 10 startups.

Accelerating Innovation: Enhancing the Economic Impact of Scientific Discovery
A vibrant, healthy economy requires innovation as well as the commercialization of innovation in the form of products, services, processes and business models that create value in the economic marketplace-what is generally considered entrepreneurship. This Science Progress article examines the dynamic innovation and entrepreneurship ecosystem that includes enablers and accelerators, as well as barriers and retardants.

Roundup: University, Community, State, National and International Initiatives

UK Budget includes Strategic Tech Investment Initiative
To help the United Kingdom out of the recession, Alistair Darling, chancellor for the exchequer for the United Kingdom, outlined several significant tech investment priorities in his budget address to the House of Commons last month, including a £750 Million ($1B USD) Strategic Investment Fund that will provide financial support, focusing on emerging technologies and regionally important sectors in advanced manufacturing, digital and biotechnology, among others.

U of Miami to Break Ground on Life Sciences Park
The University of Miami has its own stimulus plan for South Florida: a life science park set to break ground in July with the expectation of creating 4,531 permanent jobs and a $253 million annual economic output. The UM Life Science Park would house both established and spin-off companies looking to partner with university researchers.

External Resources

Final Stimulus Bill Provides $21.5 Billion for Federal R&D
The American Association for the Advancement of Science (AAAS) provides a breakdown of the final version of the 2009 economic stimulus appropriations bill, containing $21.5B in federal research and development (R&D) funding.

Are Short Drug Patents Hurting Patients?
Developing drugs takes longer than ever, but patent laws don't recognize that.

Top Ph.D. Programs, Shrinking
In March, a few institutions -- such as Emory and Columbia Universities -- announced plans to shrink the enrollment of new Ph.D. students this fall. Now it appears that a number of other universities, generally private institutions that have some of the most well regarded Ph.D. programs around, are also getting smaller.

Parting Quote

"At such a difficult moment, there are those who say we cannot afford to invest in science, that support for research is somehow a luxury at moments defined by necessities.  I fundamentally disagree.  Science is more essential for our prosperity, our security, our health, our environment, and our quality of life than it has ever been before. [...] I'm here today to set this goal:  We will devote more than 3 percent of our GDP to research and development.  We will not just meet, but we will exceed the level achieved at the height of the space race, through policies that invest in basic and applied research, create new incentives for private innovation, promote breakthroughs in energy and medicine, and improve education in math and science."

President Barack Obama, Remarks at the National Academy of Sciences Annual Meeting, April 27, 2009

University of Colorado's Office of Technology Transfer Mission Statement

The mission of the CU Technology Transfer Office is to aggressively pursue, protect, package,
and license to business the intellectual property generated from the research enterprise,
and to serve faculty, staff, and students seeking to create such intellectual property.

(303) 735-3711
ttocontact@cu.edu

http://www.cu.edu/techtransfer