University of Colorado
Technology Transfer Office
Monthly Newsletter
August 2008 - Vol 5, Issue 2
What's Inside
Spotlight
Student Connection
CU Technology in the News
People
Upcoming Events
CU Resources
Innovation in the News
External Resources
Parting Quote
Links
 
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Spotlight On:

CU-Boulder Technology of the Month:

CU2032B - Synthesis of a Polymerizable SODm to Reduce ROS Damage in Transplanted Medical Devices


TTO's Learning Laboratory

TTO Welcomes Summer Interns

Sebastian Dachenhausen joined TTO in June 2008, and has focused on supporting the start-up of 3QMatrix, a Boulder based biomedical company which recently optioned technology from TTO. He has worked with the company on their SBIR grant application and helped to assemble their first business plan; he calls this hands-on experience "fascinating" and has enjoyed the opportunity to use the skills learned in the CU-Boulder MBA program, where he will complete his MBA in spring 2009.


Julie Penner also joined TTO in June, and has split her time between the Boulder and Anschutz offices. She has worked with CU licensee Endoshape to evaluate market opportunities and create financial models in preparation for fundraising. She has also worked on market analysis for CU's Riverware software. Julie is entering her third year in CU-Boulder's MBA/JD program.
TTO LogoCU logo
Today at the TTO
Hiberna Corp. Licenses Univ. of Colorado Drug Development Technology
Hiberna Corp., a Boulder-based company developing drugs based on natural models of extreme metabolic regulation, has executed an exclusive license agreement with TTO for technology using the python as a model to identify targets and/or potential therapeutics to treat cardiac hypertrophy.

3QMatrix to Commercialize Wound Healing Technology from Univ. of Colorado
TTO executed an exclusive option agreement with 3QMatrix, Inc. for degradable thiol-ene hydrogel technology developed in the laboratories of Christopher Bowman, Associate Dean for Research, and Kristi Anseth, Distinguished Professor and HHMI Investigator, both in the Department of Chemical & Biological Engineering at the University of Colorado at Boulder. 3QMatrix is focused on the development and commercialization of novel wound healing and drug delivery products based on the proprietary thiol-ene hydrogel product platform.

TTO Reports Performance Metrics for FY2007-08
In late July, TTO released its performance metrics for the fiscal year ending June 30, 2008. Please follow the link above to a short presentation summarizing our performance, and look for our full annual report in September 2008. (See also: a recent interview with TTO leadership on w3w3.com discussing these metrics.)

CU Reaches Record Level of Research Funding
CU researchers received nearly $661M in sponsored research funding in fiscal year 2008, an upward trend that shatters previous records and reaffirms the institution's position as the leading research university in the Rocky Mountain West and one of the top in the nation. UC Denver (including Anschutz Medical Campus) topped the list with a total of $371.5M, up from $363M last year. CU-Boulder saw the largest increase in sponsored research funding, receiving a record $280.1M, compared to $266M in FY2007. CU-Colorado Springs received $9.2M, up from $7.9M last year.

TTO Accepting Proposals for Proof of Concept Investment Fall Round
The application deadline for the fall TTO Proof of Concept investment (POCi) round is Friday, October 10, 2008.  The POCi program provides early-stage "seed" investments of $100,000 to enable the further development and validation of promising CU technologies that are, or will become, the platform for a CU start-up company.  Information about the POCi program, selection criteria, application requirements, and the application form are available online; for questions about the POCi program, contact Tom Smerdon, Director of Licensing and New Business Development, 303-735-0621.

TTO Announces Deadline for Colorado State Bioscience Research Grants
The deadline to apply for a Colorado Bioscience Research Grant will be Friday, October 17, 2008. This statewide program was signed into law in April 2008, and provides $26.5M over five years to grow Colorado's bioscience industry. University researchers are eligible for awards of $50,000 to $200,000 for commercial proof-of-concept work; eligible fields include therapeutics, diagnostics, medical devices, platform technologies, and biofuels. Applications and more information are available online - for questions, please contact Rick Silva, 303-724-0222 (UC-Denver) or Kate Tallman, 303-492-5732 (CU-Boulder and CU-Colorado Springs). Important: invention disclosures must be submitted to TTO by Monday, September 22 to qualify. TTO will hold information sessions at all three campuses in early September - see events section below for dates.

TTO Accepting Proposals for Renewable Energy Proof of Concept Grants
The CU TTO now has $400,000 for Proof of Concept grants (POCg) of up to $50,000 to support the further development and validation of promising CU-Boulder renewable energy technologies. Proposals are sought in all areas related to the development of renewable and sustainable energy sources as well as efficient utilization of energy. The fall application deadline is Friday, October 24, 2008. Information about the Renewable Energy POCg program, selection criteria, application requirements, and the application form are available online; for questions, contact Kate Tallman, 303-492-5732.

TTO Hires New Biochem Licensing Associate
Paul Tabor joined the TTO as a Licensing Associate in August 2008, and is responsible for evaluating CU invention disclosures, negotiating option and license agreements, and working with inventors and industry professionals to successfully commercialize new technologies impacting human health. Prior to joining the TTO, Paul worked with pharmaceutical and venture capital clients to evaluate the commercial potential of acquisition and in-licensing targets, and also spent several years as a research scientist on the Human Genome Project. Paul earned his MBA in Finance from the University of Texas at Austin, a Master of Clinical Gerontology from Baylor University, and a BA in Chemistry and Biology from Baylor University.
CU Technology and Licensee Companies in the News

Sierra Neuropharma Pockets $21.5M in Series A
CU licensee Sierra Neuropharmaceuticals, Inc. has gained $21.5M in its Series A round; the company plans to formulate drugs that can be delivered directly to the fluid around the brain in order to provide more effective treatment for severe CNS diseases.

ARCA Banks on Heart Drug
ARCA biopharma, biotech veterans with a track record of success, may be just months away from marketing the first drug to treat heart failure by genetically identifying patients for whom the drug would work.

New Technology Aids Babies with Feeding Problems
KC BioMediX soon will begin selling sophisticated medical devices based on research by Dr. Steve Barlow (University of Kansas) and CU-Boulder's Dr. Don Finan; the company's NTrainer System essentially is a computerized pacifier that can give doctors or nurses a more accurate assessment of a baby's feeding ability before beginning therapy.

CU MicroFlex Endoscope Receives $1M STTR Grant
A University of Colorado at Boulder professor and his team, in partnership with Quest Product Development, received a $1M Phase II STTR grant from the NIH to continue developing the new MicroFlex endoscope, which will help provide a minimally invasive way to reach inaccessible parts of the body.

Archemix Expands Collaboration with Ribomic for Aptamer Therapeutic Development
CU licensee Archemix Corp., a biotech company focused on discovering, developing and commercializing aptamer therapeutics, announced in early August that it granted Ribomic Inc., a worldwide, non-exclusive license to certain of its IP rights to develop aptamers against multiple targets.

Taligen Names New CEO, Establishes Headquarters
Taligen Therapeutics has initiated a corporate growth plan with the appointment of Abbie Celniker as CEO and the establishment of its headquarters in Cambridge, MA; the company intends to build its late-stage R&D operations in Cambridge while continuing its early discovery activities in Denver.

CU Cancer Center Researchers Identify Key Cell Cycle Regulator
Researchers at the University of Colorado Cancer Center led by Dr. Jessica Tyler have identified the key marker cells use to know when broken DNA has been repaired and it is safe for the cell to begin dividing again, a discovery that could lead to new targets for cancer therapy.

New JILA Technique Reveals Hidden Properties Of Ultracold Atomic Gases
Physicists at JILA, a joint institute of the National Institute of Standards and Technology (NIST) and CU-Boulder, have demonstrated a powerful new technique that reveals hidden properties of ultracold atomic gases; this discovery may eventually have applications in efficient transmission of electricity across power grids, as well as in atomic clock and quantum computer design.

People

Chasing the Cure
Colorado has risen to the upper tier of cancer-research states - at least in terms of federal research funding, but developing new products from those discoveries and getting them to the market is a process fraught with challenges. Denver Business Journal article featuring CU faculty Dr. Paul Bunn (CU Cancer Center) and Richard Duke (GlobeImmune, ApopLogic Pharmaceuticals).

Interview: Tech Transfer Challenges, Choices and Champions
In late July, TTO released its performance metrics for the fiscal year ending June 30, 2008. This interview with the TTO leadership team covers TTO's performance and challenges, as well as its plans for the next year. Part 1.

FBBp Seeking Director of Business Development
TTO partner Fitzsimons BioBusiness Partners (FBBp) supports the growth of promising early stage bioscience businesses at the Fitzsimons Life Science District, and is seeking a business development director to help identify promising young companies and connect them to the resources they need to be successful. Full job description online (PDF).

UC Denver Assistant Professor Receives 2008 Young Investigator Award
Judith Gault, PhD, psychosis researcher and assistant professor of Neurosurgery at the UC Denver School of Medicine, was recently named a recipient of the National Alliance for Research on Schizophrenia and Depression (NARSAD) Young Investigator Award, a $60,000 grant to advance research exploring biomarkers in blood samples, which may help advance the treatments for disorders such as schizophrenia.

UCCS Announces New Appointments
The University of Colorado at Colorado Springs has announced the appointments of Dr. Michael Larson, currently the El Pomar Chair in Engineering, as the new Associate Vice Chancellor of Research and Innovation, and Dr. Jenenne Nelson, Professor of Nursing, as the new Dean of the Graduate School. These appointments fill the positions left open by Dr. Jeremy Haefner, who moved to Rochester Institute of Technology in July.

Do you know of a recent award, new position or transition of interest to the CU tech community? Please send information to TTOnews@cu.edu.

Upcoming Events

TTO New Faculty Breakfast

August 20, ATLAS Building, CU-Boulder

Join TTO for this free breakfast to welcome new faculty, and introduce them to the basics of technology transfer at CU. Open to faculty from all CU campuses - learn about the resources TTO provides to support research and commercialization initiatives. RSVP to Lindsay Polak, 303-735-5518.

 

CU-Boulder Symposium: Meeting the Global Energy and Climate Change Challenge

August 22-23, University of Colorado, Boulder

This UCB symposium will feature top national climate scientists, energy experts and environmental journalists discussing the science of climate change and the road toward a viable national energy strategy. The symposium, which is free and open to the public, includes sessions on global change prediction, carbon-free energy strategies, the social dimensions of climate change and ecological impacts of climate change.

 

Boulder/Denver New Technology Meetup Group
September 2, CU Wolf Law Building, Boulder
This ongoing event provides a forum for technologists and entrepreneurs to showcase the new (especially web-based) technology developing in Boulder/Denver tech community. Five companies have five minutes each to demonstrate their new technology, followed by five minutes for Q&A from the audience.

 

TTO Informational Roundtables: Colorado Bioscience Research Grant Program

September 3 & 4, CU-Boulder

September 8 & 11, Anschutz Medical Campus

TTO is hosting information sessions at all campuses on the Colorado Bioscience Research Grant Program, which became law in April 2008 and provides grants of up to $200,000 grants to researchers for commercial proof-of-concept work. Follow link above to session details. RSVP to Lindsay Polak, 303-735-5518.

 

Rockies Venture Club: Early Stage Investing in an Uncertain Economy

September 9, Marriott City Center, Denver
How - if at all - is investing in early stage companies impacted by the turbulence in the capital markets, the shaky economy and the upcoming election? The Rockies Venture Club has gathered some of the best minds in Colorado's early stage investment space to share their thoughts at the September meeting.

 

Optoelectronics for the Green Revolution: "Green" Photonics Forum and Exhibition

September 9-10, Sheraton Denver West, Lakewood

This conference, hosted by the Optoelectronics Industry Development Association (OIDA), will explore the key technologies and showcase companies that will enable optoelectronics to play a major role in the green revolution.

 

CBSA BioBoulder
September 10, Rembrandt Yard, Boulder
Join the Colorado BioScience Association, Hogan & Hartson and VCFO to toast the end of summer, and the final BioBoulder event of 2008!

 

Colorado Green Tech Meetup

September 11, Leeds School of Business, Boulder

An ongoing event to support eco-entrepreneurs and others people involved and/or interested in green tech: energy generation, transportation, construction, and efficiency technologies. Businesses and researchers present new technologies, and attendees may announce business news, job openings, fundings, etc.

 

First Annual Rocky Mountain POSSE: Photonics and Optics Summit and Special Event

September 11, Sheraton Denver West, Lakewood

POSSE is a regional event, bringing in 100 or more business leaders from throughout the Rocky Mountain region to network, learn from each other, help keep the photonics industry growing, and celebrate its resiliency.

 

CBSA 2008 BioScience Bogie Golf Tournament
September 15, Omni Interlocken Golf Club, Broomfield

Join your bioscience colleagues and friends for a great day of golf while you show your support for the industry and for the CBSA internship program. Info and registration online.

 

Entrepreneurs Unplugged

September 17, CU Engineering Center, Boulder

Ongoing networking event hosted by CU's Silicon Flatirons Center, providing faculty, students and community members with technical backgrounds the opportunity to learn about entrepreneurship through the experiences of a successful local entrepreneur.

 

TTO Workshop: SBIR and STTR Grants

September 19, ATLAS Building, CU-Boulder

Join TTO and SBIR/STTR guru Russ Farmer of PBC, Inc. to learn more about these federal grants available to help commercialize your work. Details online, or RSVP to Lindsay Polak, 303-735-5518.

 

TiE-Rockies Mentorfest

September 24, PPA Event Center, Denver

Mentorfests are group mentoring and networking events at which successful entrepreneurs and business leaders share their knowledge and experience with next generation entrepreneurs and professionals.

 

CTEK Angels LIVE!

September 25, Davis Auditorium, University of Denver

This event allows the general public to obtain an insider's perspective into what angel investors look for in a deal, what gets them excited about an opportunity, what they shoot down quickly, and how the angel process is organized.

 

TTO New Faculty Breakfast

September 26, Anschutz Medical Campus, Aurora

Join TTO for this free breakfast to welcome new faculty, and introduce them to the basic of technology transfer at CU. Open to faculty from all CU campuses - learn about the resources TTO provides to support research and commercialization initiatives. RSVP to Lindsay Polak, 303-735-5518.

 

Homeland Defense Emerging Technology Day

October 27, Broadmoor Hotel, Colorado Springs

This conference, sponsored by the Colorado Homeland Defense Alliance (CHDA), will feature presentations of technical papers and a presentation on "Bridging the Gap Between HS/HD Needs and Your Emerging Technology". Presentations from various government agencies will identify technology capabilities they have identified as high priority for Homeland Security/ Defense, and some ways to pursue business opportunities with them to mature these emerging technologies. For more information, contact Roger Neeland.

 

Call for Presentations: 21st NREL Industry Growth Forum

October 28-30, Denver

NREL and its partners are now accepting applications from clean energy companies who would like to present to an audience of the country's leading clean energy investors at the upcoming 21st NREL Industry Growth Forum. Application info online.

 

To have your event featured here, please send an email to TTOnews@cu.edu.

CU Resources

Silicon Flatirons Center for Law, Technology and Entrepreneurship
One of the basic goals of the Silicon Flatirons Center at CU-Boulder is to facilitate networking, the development of "human capital" and the promotion of entrepreneurship in the Colorado technology community, and to inspire student interest in technology law and entrepreneurship. Through the Center's myriad programs, including support for the Entrepreneurial Law Clinic, a campus-wide business plan competition, the New Technology Meetup, the Entrepreneurs Unplugged series, and the Crash Course for Entrepreneurs series, the Center establishes venues to address the development of skills necessary for building or counseling successful entrepreneurial ventures, and creates networking opportunities to bridge the University and local communities.

Through Silicon Flatirons, students from the Law School, the Interdisciplinary Telecommunications Program, Computer Science, Journalism, the Business School, ATLAS, and other departments have been matched up with outside professional mentors. The Center continues to work on developing internship opportunities for students interested in these areas.
Innovation in the News

Putting Drug Development In Patients' Hands
A WSJ article about the recent phenomenon of patient-supported research - a trend largely driven by people wealthy enough to help fund drug-discovery projects and who are affected by rare or overlooked diseases.

VC-Owned Firms Could Receive SBIR/STTR Awards Under New Deal
Small companies owned by venture capital firms would again be eligible for research and development funding from federal agencies under a compromise deal reached in the Senate for the Small Business Innovation Research reauthorization bill, which the full Senate is expected to approve in September.

Microsoft Must Face University Patent Infringement Suit
Microsoft Corp., the world's biggest software maker, must face a lawsuit accusing the company of infringing three patents for a process developed at the University of Rochester to improve images on computer screens, an appeals court ruled in August, reversing a previous finding that the patents, now owned by Research Corporation Technologies Inc., couldn't be enforced.

Roundup: University, Community, State, National and International Initiatives

Chinese Consortium Formed for Early Stage Biotech Investment
A combination of public and private Chinese entities have banded together to form a loosely organized investment consortium that will focus on early stage biotech enterprises.

GSK and Harvard Team to Develop Stem Cell Therapies
U.K.-based pharmaceutical giant GlaxoSmithKline plc will pony up at least $25M over five years to the Harvard Stem Cell Institute for research collaboration in the field of stem cell science to develop new medicines.

External Resources

LES Survey Benchmarks Biopharma Licensing Deals
The Licensing Executives Society recently released its first LES BioPharmaceutical Royalty Rates and Deal Terms Survey." The survey analyzes more than 150 recent U.S. and Canadian deals involving universities, pharma companies and biotechs.

Turning Clean-Tech Engineers Into Entrepreneurs
If you're an investor with money to burn, environmental technology has become the biggest game in town; the problem is, there are few rogue entrepreneurs with the chops to handle the complexities of environmental technology, much less to invent it.

The Economics of Biotech Licensing
Understanding why licensing works in biotech, and why deals are structured as they are, will help the entrepreneur negotiate.

Parting Quote
 
"Out there is an entrepreneur who is forging a bullet with your company's name on it. You've got one option now -- to shoot first. You've got to out-innovate the innovators."
 
-Gary Hamel, management consultant and author.
 
 

University of Colorado's Office of Technology Transfer Mission Statement

The mission of the CU Technology Transfer Office is to aggressively pursue, protect, package,
and license to business the intellectual property generated from the research enterprise,
and to serve faculty, staff, and students seeking to create such intellectual property.

(303) 735-3711
ttocontact@cu.edu

http://www.cu.edu/techtransfer