Adiponectin, adiponectin receptors, adiponectin binding proteins: players in unlocking good & bad health?
Dear Doctor
Adiponectin is a cytokine produced primarily by adipose tissue (hence being termed an adipokine) and expressed at high levels (0.01% plasma protein Matsuzawa et al 2004) in normal, healthy, but lean, people.
Research since its discovery by Scherer et al (1995) has linked Adiponectin to a myriad of biological functions and influences ranging from possible roles in apoptosis and mediating proinflammatory cytokines like TNFalpha, to playing a central role in our energy metabolism, vascular health, insulin regulation and the mediation of metabolic disease. |