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Dear Doctor,

This newsletter highlights some of our well characterized antibodies against proteins involved in neurotransmitter synthesis important for normal brain function as well as in Alzheimer's disease (AD), Parkinson's disease (PD) and other neurodegenerative disorders that are characterized by effects on cholinergic, dopaminergic and other neurons in the brain.

R-118-100Rabbit antibody to Tyrosine Hydroxylase (TH)

Immunohistochemical staining of catecholaminergic neurons in the rat brain stem using rabbit antibody to tyrosine hydroxylase (R-118-100).
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See also our monoclonal antibody to Tyrosine Hydroxylase (M-1154-100).
anti-DBH biosensis AbDopamine Beta Hydroxylase (DBH)

Immunohistochemical staining of DBH (R-108-100) in guinea pig brain stem. This antiserum has been extensively characterized in many laboratories. It reacts with a single band on Western Blot of bovine adrenal homogenates and stains only cells known to contain DBH such as sympathetic neurons, adrenal medullary cells and central adrenergic neurons.
Biospeak: Alzheimer's titleRabbit antibody to Orexin A

An exceptional antibody for immunohistochemistry. Immunohistochemical staining of orexin A in rat zona incerta neurons using rabbit antibody to Orexin A (R-104-100) at a dilution of 1 in 1000.
M-1155-100 Mouse monoclonal antibody to Tryptophan Hydroxylase [Try-63]: IgG

Western blot using mouse antibody to Tryptophan Hydroxylase (M-1155-100) on rat brain tissue lysate at 1 μg/ml. Secondary HRP conjugated goat anti-mouse IgG antibody at 1:3000.

Rabbit ChATRabbit antibody to Choline Acetyltransferase (ChAT)

Immunofluorescent staining of rat basal forebrain cholinergic neurons using rabbit ant-ChAT primary (R-043-100) and Cy3 secondary antibodies. This antibody has been used for the detection of cholinergic neurons across the nervous system. It stains both cell bodies and nerve terminals.
In This Issue
Tyrosine Hydroxylase
Dopamine Beta Hydroxylase
Orexin A
Tryptophan Hydroxylase
ChAT
Antibody Quick Links

Apoptosis

Autophagy

Cancer

Growth Factors

Stem Cells

Neurotrophic Factors

Diabetes & Obesity
BioSpeak

Each month, our BioSpeak newsletters highlight recent progress in important research areas such as:
  1. Avoiding manuscript rejection
  2. Semaphorins
  3. Autophagy
  4. Stem Cells
  5. Alzheimer's Disease
  6. Neurotrophins
  7. Motor Neuron Disease
Question of the month

Question: Do your tyrosine hydroxylase antibodies (R-118-100 and M-1154-100) work for IHC?

Answer: Both antibodies have been tested on paraffin embedded AND frozen sections  and work beautifully. Both are superb antibodies for detection of tyrosine hydroxylase containing neurons exhibiting an intense labeling with a negligible background in brain and peripheral tissues. They can both be used across species.
Closing Headline
Web site guarantee logoShould your manuscript ever be rejected by ANY journal because of insufficient information about a Biosensis antibody, we will gladly refund TWICE the purchase price of that antibody!

By researchers for researchers!

Our staff have over 60 years experience in the manufacture and use of antibodies, having published over 340 peer reviewed research publications. So, if you have a query on any of our antibodies, please contact us at biospeak@biosensis.com.
 
Sincerely,
Tina
Contact Information
Email: tina@avibiomail.com
Phone: + 61-43-166-5519
Web: www.biosensis.com