Is your antibody fully characterized?
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Many top journals are now refusing to publish submitted manuscripts if the antibodies used in the research have not been fully characterized. Take a look at some recent editorials and related articles:
"Because work using these antibodies is inherently not repeatable, such papers are not acceptable for publication" Clifford Saper, Editor-in-Chief J Comp Neurol 2005 493:477-478 "An open letter to our readers on the use of antibodies" Abstract
"Sometimes for 'proprietary' reasons, details on the antigen are withheld. This is not good science and we should boycott those antibodies" John Couchman J Histochem Cytochem 2009 57:7-8 "Commercial antibodies: The Good, Bad and Really Ugly" Abstract
"The
minimal set of information that should be provided in scientific
publications to allow proper evaluation and replication of
immunohistochemical experiments includes the precise and complete
description of the primary antibody (host species, nature of the
antigen and its preparation), provenance and characterization of its
specificity (explicit description or citation of the relevant
manufacturer information and references to published data)." Fritschy JM Eur J Neurosci 2008 Dec;28(12):2365-70 "Is my antibody-staining specific? How to deal with pitfalls of immunohistochemistry" Abstract
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Knowing the immunogen is critical
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A guide to the perplexed on the specificity of antibodies
Clifford Saper, J Histochem Cytochem 2009 57:1-5 Abstract
Lack of specificity of commercially available antisera: better specifications needed
Pradidarcheep W et al J Histochem Cytochem 2008 Dec;56(12):1099-111 Abstract
Specificity controls for immunocytochemistry
Holmseth S et al Anat Embryol (Berl) 2006 Aug;211(4):257-66 Abstract
New article category in anatomy and embryology: methodological standards
Bjaalie JG and Zilles K Anat Embryol (Berl) 2006 Aug;211(4):255 Abstract
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Can you publish in NATURE?
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With Biosensis antibodies you can submit your manuscripts with confidence.
Biosensis antibodies have been published in NATURE and SCIENCE.
Cooney et al Nature Medicine 2010 Jan;16(1):90-7
Abstract - Antibody used R-158-100
Rabizadeh et al Science 1993 261 Abstract - Antibody used M-006-100
Le Sauteur et al Nature Biotechnol 1996 Sep;14(9):1120-2 Abstract - Antibody used M-957-100
Wiese et al Nature Protocols 2010 5(1):31-8 Abstract - Antibody used M-009-100
Birren et al Science 1992 257:395-7 Abstract - Antibody used M-006-100
Because we care about your research:
- Biosensis will NOT compromise on quality
- Biosensis will NOT sell uncharacterized antibodies
- All Biosensis antibodies have sufficient details to allow them to be published in ANY journal
- Biosensis discloses antigen details (even though our competitors use this information)
- Biosensis product sheets ONLY contain REAL data obtained using the antibody
- Biosensis has a team of experienced researchers ready to help with your inquiries
- Biosensis is committed to seeing our antibodies used in your top quality research
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The Biosensis UNCONDITIONAL Guarantee
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Should
your manuscript ever be rejected by ANY journal because of insufficient
information about a Biosensis antibody, we will gladly refund TWICE the
purchase price of that antibody!
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By researchers for researchers!
Our staff have over 60 years experience in manufacturing and using
antibodies and over 340 peer reviewed research
publications.
If you have any questions, one of our experienced researchers is always there to help at biospeak@biosensis.com.
Until next time, good luck with your research.
Sincerely,
Tina
P.S. Have you missed previous issues of BioSpeak? Click Here
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