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Greetings!
Stem cells proliferate, migrate, and differentiate to form
organisms during embryogenesis. Since their identification
and characterization, stem cell therapy has promised to dramatically change the treatment of numerous human diseases including cancer, neurodegenerative diseases, musculo-skeletal diseases, cardiac disease and rheumatoid arthritis.
This issue of BioSpeak highlights the most recent progress in the area of Stem Cell research.
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Neural progenitor cells.
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1. SOX6 controls dorsal progenitor identity and interneuron diversity during neocortical development. Azim E, Jabaudon D, Fame RM, Macklis JD. Nat Neurosci. 2009 Aug 5.[Epub ahead of print] Abstract
2. Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein. Desplats P, Lee HJ, Bae EJ, Patrick C, Rockenstein E, Crews L, Spencer B, Masliah E, Lee SJ. Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):13010-5. Epub 2009 Jul 27.
Abstract
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The importance of mTor signalling in stem cell exhaustion and mammalian aging.
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mTOR mediates Wnt-induced epidermal stem cell exhaustion and aging.
Castilho RM, Squarize CH, Chodosh LA, Williams BO, Gutkind JS. Cell Stem Cell. 2009 Sep 4;5(3):279-89.
Abstract
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Rapamycin fed late in life extends lifespan in genetically heterogeneous mice.
Harrison DE, Strong R, Sharp ZD, Nelson JF, Astle CM, Flurkey K, Nadon NL, Wilkinson JE, Frenkel K, Carter CS, Pahor M, Javors MA, Fernandez E, Miller RA. Nature. 2009 Jul 16;460(7253):392-5. Epub 2009 Jul 8.
Abstract
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Stem cells and cancer.
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5.
A luminal epithelial stem cell that is a cell of origin for prostate cancer.
Wang X, Julio MK, Economides KD, Walker D, Yu H, Halili MV, Hu YP, Price SM, Abate-Shen C, Shen MM. Nature. 2009 Sep 9. [Epub ahead of print]
Abstract
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So if you have a Stem Cells reagent related question, email one of our experienced researchers at biospeak@biosensis.com.
Help for researchers from researchers! Our staff have over 60 years experience in manufacturing and using
antibodies and have published over 340 peer reviewed research
publications.
"Good luck with your research"
Sincerely,
Tina!
P.S. Have you missed previous issues of BioSpeak? Click Here
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