Rat spinal cord showing upregulation of p75 Neurotrophin receptor 
after peripheral nerve injury.

The figure shows motor neurons within the lumbar spinal cord of the 
rat, stained with the anti-rat p75NTR antibody, MC192 and 
HRP-conjugated secondary antibody. Upregulation of p75NTR is seen in 
motor neurons ipsilateral to a sciatic nerve injured (by crush) 7 
days earlier, whereas un-injured motor neurons on the contralateral 
side contain no p75 receptor. Note also the prominent staining of 
sensory nerve terminals within the dorsal horn, as many primary 
afferents normally contain the p75NTR receptor.