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Kidney Beginnings: The Electronic Newsletter
In This Issue
Medal of Excellence Tickets Now Available
Investigational Drug May Reverse CKD
Attend a Kidney Beginnings: Live Program Near You!
Post Heart Attack, Patients with Lower Kidney Function Not Taking Prescribed Meds
Update on the AAKP Annual Convention
Mammograms May Help Assess Heart Risk in Kidney Patients
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Medal of Excellence Tickets Now Available!
Moe 2011

Tickets for the 2011 AAKP Medal of Excellence Award Dinner are now available for purchase. During this event, AAKP will honor Raymond M. Hakim, PhD, MD, and Allen Nissenson, MD, FACP for their extraordinary devotion and skills in the renal field.

 

The Medal of Excellence Award Dinner takes place March 18, 2011, at the Marriott Wardman Park Hotel in Washington, DC. The Dinner is being held in conjunction with the Renal Physicians Association Annual Meeting. 
 
To purchase tickets for the Medal of Excellence, please contact AAKP at (800) 749-2257 or click here to purchase tickets online.

February 2011
masthead
Investigational Drug May Reverse CKD
Recent trial data suggests an investigational agent called bardoxolone methyl may improve renal function in type 2 diabetics with moderate to severe chronic kidney disease (CKD). Researchers enrolled 227 such patients in a 52-week trial. All patients were receiving standard care prior to randomization. At 24 weeks, 60 percent of patients who received the drug had a decrease in the classification of the severity of their CKD compared with only 17 percent of patients who received a placebo. These findings showed that treatment was effective in patients with advanced disease and those more likely to progress.

 

The increases in eGFR in the treatment group were accompanied by decreases in blood urea nitrogen, serum phosphorus, and uric acid. The encouraging results suggest bardoxolone methyl has the potential to change the treatment landscape of CKD. The drug may make it possible to delay the onset of end-stage renal disease. Researchers expect a phase 3 study to begin in the first half of 2011.

Attend a Kidney Beginnings: Live Program Near You!
KB LiveKidney Beginnings: Live is heading to Little Rock, AR; Chicago, IL; and Dallas/Fort Worth, TXKidney Beginnings: Live is a FREE educational program designed to educate individuals about the basics of kidney disease and proper kidney care. Attendees receive complimentary educational materials, learn about kidney disease in a welcoming atmosphere and have the opportunity to have questions answered by local health care professionals.

Please visit the AAKP websiteto register for a program and for more upcoming locations and dates.  
 
The supported activity is sponsored by an educational donation provided by Amgen, Inc. and Abbott Laboratories.
Post Heart Attack, Patients with Lower Kidney Function Not Taking Prescribed Meds 
meds

Among older adults with a recent heart attack, those with lower levels of kidney function are less likely to take their medications as prescribed, according to a study in the Clinical Journal of the American Society of Nephrology (CJASN). Several types of medications have proven benefits for preventing recurrent heart attacks. The researchers studied 2,103 patients aged 65 or older with a recent heart attack. Pharmacy insurance claims records were used to determine the percentage of days that patients actually had their prescribed medications. Over three years' follow-up, the patients had their prescribed drugs for only 50 to 60 percent of the time. For ACEIs/ARBs and beta-blockers, medication adherence was significantly lower for patients who had lower levels of kidney function at the beginning of the study.

Update on the AAKP Annual Convention! 
Little Rock

AAKP is planning a combined public policy event and enhanced Annual Meeting for August 2011. AAKP has planned its initial public policy forum to be held at the William J. Clinton Presidential Center in Little Rock, Arkansas. We will invite national policy, medical and academic experts to discuss and debate preventive medicine and health considerations among minority communities who are disproportionately impacted by  chronic kidney disease (CKD). 

 

Immediately following the public policy forum at the Clinton Presidential Center, we will begin the 2011 AAKP Annual Meeting. Building on the successes of the 2010 Convention, we will involve specific tracks/sessions to meet the needs of a wide range of current and future patients, their families and caregivers and various professional groups. Hotel agreements are currently being finalized and we will soon provide further information about the venue and accommodations for this program. We hope you plan on joining us at the 2011 Annual Meeting and helping AAKP move forward in its patient education and public policy efforts.

Mammograms May Help Assess Heart Risk in Kidney Patients
Routine mammograms performed for breast cancer screening could serve another purpose as well: detecting calcifications in the blood vessels of patients with advanced kidney disease, according to a study in the Clinical Journal of the American Society of Nephrology (CJASN). Mammograms show calcium deposits in the breast arteries in nearly two-thirds of women with end-stage renal disease (ESRD). Arterial calcium deposits may contribute to the high rate of death from heart disease in patients with CKD and ESRD. In addition to calcifications of the inner layer of the blood vessels, calcifications can also occur in the middle layer. These middle layer calcium deposits may contribute to cardiovascular disease risk by making the arteries stiffer, but they can be difficult to detect.

 

When the researchers reviewed routine mammograms performed in women with ESRD, they found breast arterial calcifications in 63 percent of patients. In contrast, in a group of women without kidney disease, they were found in just 17 percent of cases. Thirty-six percent of the women with kidney disease already had breast arterial calcifications on mammograms performed several years earlier before their kidney disease advanced to ESRD. Since most women with CKD are at an age where yearly mammograms are recommended, mammograms may be a useful tool for studying the development and progression of medical calcifications.