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Kidney Beginnings: The Electronic Newsletter
In This Issue
Take Charge of Your Healthcare with My Health
Low Income Associated with High Phosphate Levels in CKD
Attend a Kidney Beginnings: Live Program Near You!
Aspirin Reduces Cardiac Events, Mortality in Kidney Patients
New Warnings Required on Use of Gadaolinium-Based Contrast Agents
Lack of Access to Healthy Food May Contribute to Health Disparities in Kidney Disease
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Take Charge of Your Healthcare with
 My Health™
MyHealth
AAKP My Health™ features new tools to help you take charge of your health!
 
 Now you can print an emergency contact card and receive doctor appointment reminders!
 
 The site also allows you to:
 
· Track your lab results
· Log your medications
· List your healthcare team members
· Prepare information for doctor visits
· Test your kidney knowledge
 
Log on now to www.aakp.org to register. It's FREE and EASY!
 
AAKP My Health™ is supported by Amgen, Inc., Astellas Pharma US, and Genzyme.
 
October 2010 
masthead
Low Income Associated with High Phosphate Levels in CKD
According to research published in the Journal of the American Society of Nephrology, lower socioeconomic status is associated with hyperphosphatemia. This may mean low income patients eat more relatively inexpensive processed and fast foods containing increased levels of phosphate. The research found that this is true for both black and white patients with chronic kidney disease (CKD). Researchers conducted a cross-sectional analysis of race, socioeconomic status, and serum phosphate level in 2,879 participants in the Chronic Renal Insufficiency Cohort Study.

The researchers found that unemployed participants and those with the lowest incomes were significantly more likely to have higher serum phosphate levels than those who were employed or had the highest incomes. Racial differences in serum phosphate levels were observed, but after adjustment for income, this relationship was modified; blacks had 0.11 to 0.13 mg/dL higher serum phosphate than whites in the highest income groups, but there were no racial differences in the lowest income group. Also, compared with the highest-income whites, both whites and blacks with the lowest incomes were more than twice as likely to have hyperphosphatemia.
Attend a Kidney Beginnings: Live Program Near You!
KB LiveKidney Beginnings: Live is heading to Phoenix, AZ, on October 9th. Kidney Beginnings: Live is a FREE educational program designed to educate individuals about the basics of kidney disease and proper kidney care. Attendees receive complimentary educational materials, learn about kidney disease in a welcoming atmosphere and have the opportunity to have questions answered by local health care professionals.
 
Please continue to check the AAKP website for more upcoming locations and dates.
 
The supported activity is sponsored by an educational donation provided by Amgen, Inc. and Abbott Laboratories.
Aspirin Reduces Cardiac Events, Mortality in Kidney Patients
aspirinAntiplatelet therapy in chronic kidney disease (CKD) patients with high blood pressure significantly reduces cardiovascular events and mortality, according to research published in the Journal of the American College of Cardiology. Researchers analyzed data from the Hypertension Optimal Treatment (HOT) study for subjects with diastolic hypertension who had been randomized to aspirin or placebo. The study focused on patients for whom baseline serum creatinine values were available.
 
The researchers found that major cardiovascular events were reduced by 9 percent for those with baseline eGFR of 60 ml/min/1.73 mē or greater, by 15 percent for those with eGFR of 45 to 59 ml/min/1.73 mē, and by 66 percent for those with eGFR below 45 ml/min/1.73 mē. For the same eGFR levels, mortality was reduced by 0, 11, and 49 percent, respectively.
New Warnings Required on Use of Gadolinium-Based Contrast Agents
MRIThe U.S. Food and Drug Administration is requiring that gadolinium-based contrast agents (GBCAs) carry new warnings on their labels about the risk of a rare and potentially fatal condition known as nephrogenic systemic fibrosis (NSF), if the drug is administered to certain patients with kidney disease. Three of the GBCAs - Magnevist, Omniscan, and Optimark - will be described as inappropriate for use among patients with acute kidney injury or chronic severe kidney disease. All GBCA labels will emphasize the need to screen patients to detect these types of kidney dysfunction before administration.
 
NSF is a condition involving the formation of excess fibrous connective tissue in the skin, joints, eyes, and internal organs. Symptoms of NSF can include scaling, hardening and tightening of the skin, red or dark patches on the skin, and stiffness. NSF may lead to death, especially if it involves body organs. Data suggest that NSF may follow the administration of any GBCA and the FDA continues to assess the safety of each GBCA to better estimate its NSF risks.
Lack of Access to Healthy Food May Contribute to Health Disparities in Kidney Disease
fast foodProcessed and fast foods enriched with phosphorus additives may play a role in health disparities in chronic kidney disease, according to a new study. Previously, genetics was considered the leading reason blacks are four times more likely to progress to end stage renal disease than whites and have much higher rates of cardiovascular disease and mortality in early chronic kidney disease (CKD).

Phosphorus, a mineral found naturally in foods such as milk, cheese, beans and peanut butter, is vital for the formation of bones and teeth, as well as energy production and the formation of cell membranes. Since the kidneys excrete excess phosphate, patients with CKD may develop increased blood levels of phosphate, or hyperphosphatemia. Manufacturers add phosphates to foods to give them a longer shelf life and make them more appealing. The amount of phosphorus additives in food is not always listed, so people unknowingly ingest more phosphorus than they probably should. The study appears in the Journal of the American Society of Nephrology (JASN).