A Recipe for Alzheimer's Disease

by Duane Graveline MD, MPH 

The so-called glial cells of the brain, long suspected of providing certain housekeeping functions, have been shown to produce their own supply of cholesterol for the specific purpose of providing nerve cells with a vital synaptic component.

Since the brain cannot tap the cholesterol supply in the blood because the lipoproteins that mediate the transport of cholesterol are too large to pass the blood-brain barrier, the brain must depend upon its own cholesterol synthesis, which the glial cells provide. 

The highly lipophilic statin drugs such as Lipitor®, Mevacor® and Zocor® far more easily cross the blood-brain barrier and interfere with glial cell synthesis of cholesterol than their hydrophilic counterparts such as Pravachol®.  

Cholesterol & Triglyceride Converter

Cholesterol and Triglyceride values in the United States are expressed in mg / dL and in Canada, the UK and Australia in mmol / L. 
To use the Cholesterol and Triglyceride Converter, enter a value and click on the Convert button to see the Cholesterol or Triglyceride  level expressed in the other standard. 

Blood Glucose Converter

Blood Glucose values in the United States are expressed in mg / dL  and in Canada, the UK and Australia in mmol / L. 
To use the Blood Glucose Converter, enter a value and click on the Convert button to see the blood glucose level expressed in the other standard.  

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The Statin Damage Crisis