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Spacedoc Newsletter
January 5, 2011 |
| PQQ and Statin Damage | |
 Those of you who have been following my research during the past two years will know that I consider mitochondrial DNA damage as the ultimate result for some of statin drug intake.
Through mevalonate blockade, statins directly inhibit CoQ10 synthesis making mitochondrial damage and mutation all but inevitable. Furthermore, the inhibitory effect of statins on dolichol synthesis makes repair of DNA damage all the more difficult because of dolichol's vital role in glycoprotein (glycohydrolase) synthesis.
Recently I have learned of another biochemical substance that also is implicated in this process of mitochondrial maintenance. The name of this biochemical is pyrroloquinoline quinone with the shorthand version being PQQ.
One promotion for PQQ begins with, "The more functional mitochondria you have in your cells, the greater your overall health and durability," which is the premise of my new e-book, The Dark Side of Statins, so my interest in this substance is obvious.
PQQ and Statin Damage
Duane Graveline MD MPH
Former USAF Flight Surgeon
Former NASA Astronaut
Retired Family Doctor
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| The Dark Side of Statins: e-Book by Dr Duane Graveline, M.D. | |
All three of my previous statin books are now available in e-Book versions plus my latest book The Dark Side of Statins which is available in e-Book only for now.
e-Books offer a lower cost way to get the same information as in the print versions, allow readers from all over the world instant access, and now you do not even need an electronic bookreader as these versions can be read on any device like smart phones, tablet computers, laptops and desktops.
The Dark Side of Statins
Try to imagine a drug possessing the ability to cause DNA mutations using the same mechanisms that have evolved for natural aging. When confronted with a patient experiencing weakness and unsteadiness, muscle aches and pains, memory loss and depression, the quite natural response from most doctors is, "You have to expect this kind of thing now; you are over 50".
Most doctors do not have a clue as to the truth. It is not natural aging that has depleted you so. This is premature aging - aging in months according to many statin victims - and this entire complex of symptoms from a drug so safe that many doctors feel it should be put in the drinking water.
The class of drugs is called statins, simple reductase inhibitors capable not only of lowering cholesterol but also CoQ10 and dolichols as well, leading directly to mitochondrial damage and mutation. No, this is not impossible. It is happening today to thousands of us.
The Dark Side of Statins, 25,000 words, published October, 2010
Duane Graveline MD MPH
Former USAF Flight Surgeon
Former NASA Astronaut
Retired Family Doctor
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| Books by Dr Duane Graveline, MD MPH | | Advertisement |
The Statin Damage Crisis
by Duane Graveline MD MPH
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Statin Drugs Side Effects and the Misguided War on Cholesterol
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Lipitor Thief of Memory
by Duane Graveline by Duane Graveline, M.D.
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From Laika With Love
by Duane Graveline MD MPH
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