Spacedoc Newsletter
March 24, 2010  
Blood Pressure: How Low is Too Low?
 
Dr Graveline
For thirty years I had been completely satisfied with a 140/90 standard as the upper limit of normal blood pressure established long before I was in training in the 1951-1955 era.

Throughout my 30 years of medical practice this target served me well. With experience I confidently made small adjustments to better serve my patients.

For those over 60 years of age, I felt justified in raising the acceptable systolic standard to 150 as a general rule and giving increasing importance to the diastolic before making my decision to start blood pressure medication.

The diastolic would generally have to be 95 for me to start writing prescriptions.  After all, we are talking expensive, side effect prone drugs for the rest of the patient's life - a not inconsiderable consideration.
 
Duane Graveline MD MPH
Former USAF Flight Surgeon
Former NASA Astronaut
Retired Family Doctor  
 
High Dose Statins and Muscle Injury

On March 19, 2010, the FDA issued a Safety Announcement that begins:
 
"Based on review of data from a large clinical trial and data from other sources, the U.S. Food and Drug Administration (FDA) is informing the public about an increased risk of muscle injury in patients taking the highest approved dose of the cholesterol-lowering medication, Zocor (simvastatin) 80 mg, compared to patients taking lower doses of simvastatin and possibly other drugs in the "statin" class." 
 
The full Safety Announcement is on the FDA website at:
fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm204882.htm
 
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For years I have been writing on the side effects of statins, particularly at the "cholesterol busting" high doses. Muscle pain and permanent muscle damage has always been a concern.
 
These are some of the articles on the spacedoc.net site that readers may find relevant and of interest.

Muscle Pain and Statins
 

 
Duane Graveline MD MPH

Former USAF Flight Surgeon
Former NASA Astronaut
Retired Family Doctor  
 
Links in this Newsletter
Books by Dr Duane Graveline, MD MPH
Advertisement 
The Statin Damage Crisis
by Duane Graveline MD MPH
Paperback
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Statin Drugs Side Effects and the Misguided War on Cholesterol 
by Duane Graveline MD MPH
Paperback
 
 
 
 
 
Lipitor Thief of Memory 
by Duane Graveline by Duane Graveline, M.D.
Paperback

From Laika With Love
by Duane Graveline MD MPH
Paperback
Buy Now
 
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