Spacedoc Newsletter
June 30, 2009  
 
Blood Pressure, Personality, and Heart Attack Risk 
If you just happen to be a Type A personality, the effect of talking during the taking of blood pressure can be extreme. 
 
Now that we have learned more about this, we find that everybody's blood pressure tends to spike with speaking.
 
Also, speech intensity and volume as affected by emotion or high ambient noise levels can greatly augment this tendency. Other contributory factors are content of the talk and social quality of the audience.  
 
Long have we wondered why some people have strokes and heart attacks despite having a diagnosis of normal blood pressure and this type A personality tendency with a lifetime of blood pressure surges could be one reason. 

Duane Graveline MD MPH
Former USAF Flight Surgeon, Former NASA Astronaut, Retired Family Doctor 
 
Dr. Kilmer McCully, M.D. - Infections and Vulnerable Plaques
 
Dr. Kilmer McCully M.D. has written a series of articles for spacedoc.net. 
The first was on Cholesterol, the second was on Homocysteine and the third and final installment is on Infections and Vulnerable Plaques. 

Vulnerable plaques are a phase in the natural development of atherosclerotic disease when the plaque material is composed primarily of platelets that have aggregated but still lack the stabilizing effect of fibrin connective tissue threads, which take more time to accumulate, so the clotted matter can easily be  dislodged.

The term "vulnerable" applies particularly to this unstable phase of development when many different factors can combine to cause fragments of various size to break free of the parent mass and abruptly enter the (arterial) circulation traveling only so far until further progress is impeded by its size, at which point it is stopped, plug-like, to suddenly deprive a segment of cardiac muscle tissue of vital nutrients (infarction).

If this is sustained for more than a short while, muscle damage becomes irreparable causing weakening of the heart as a pump or immediate death by the irritative effect of the injury, often by inducing arrhythmias, ventricular tachycardias (fast heart) or fibrillation (completely irregular heart) incompatible with life.

Infections and Vulnerable Plaques - Pt.1
Kilmer S. McCully, M.D.
Chief, Pathology and Laboratory Medicine Service
West Roxbury Veterans Affairs Medical Center
 
  
Books by Dr Duane Graveline MD MPH
Advertisement
"The Statin Damage Crisis" by Dr Duane Graveline M.D.

BooksDr Graveline's third book on statins called "The Statin Damage Crisis" is now available.
 
Originally planned as a new edition to "Statin Drugs Side Effects," it has been released as a stand alone title so that the highly relevant material in "SDSE" will still be available.

Dr Graveline wrote the following introduction to this latest title:
 
Early on my NASA doctors told me my amnesia response to statins was nothing but a coincidence but I persevered to write my first book, "Lipitor, Thief of Memory" and now find that over 1,000 cases of amnesia and memory loss have been reported to the FDA, just from Lipitor alone.
 
Then I learned of statin damage to nerves and muscles and profound behavioral and personality changes, demanding I write a second book, "Statin Drugs Side Effects." Even this broadly encompassing book was insufficient to describe what I have learned more recently of the truly dark side of statins - their ability to alter the very fabric of our makeup.
 
I had long wondered why muscle and nerve damage seemed permanent and even progressive like my own ALS-like condition. Now I have found that the ultimate effect of statins on CoQ10 and dolichols is to damage the DNA of the mitochondrial life - force within our cells - mitochondrial mutation masquerading as premature old age. 
 
Duane Graveline MD MPH
Former USAF Flight Surgeon, Former NASA Astronaut, Retired Family Doctor 
 
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