Issue: #4November 2011



- Words to Live By 
- The New Anion Relay Chemistry
- High-tech in the First State     
- 3 Easy Ways to Search Our Online Catalog
- Visit Adesis at Informex 2012-Now Scheduling Meetings
- End of Year Spending Incentives 
- New Compounds for November -  Always In Stock!


In This Issue
Blogs, Seminars, and Round-tables
3 Easy Ways to Search Our Online Catalog
Informex 2012
End of Year Spending
Compounds of the Month
November Promotion


catalog e-news



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Adesis Whitepaper

oct poster

Efficient Methods for Regioselective 

Functionalization of 

6-Substituted Furo[3,2-b] pyridines for Indole Isosteres.  



Quick Links







Blogs, Seminars, and Round-tables 



Blogs: An oldie but a goodie.  Here is a Blog post from Derek Lowe's In The Pipeline Blog from March 18th 2010.  A colleague forwarded the original post to us some time ago, but just last week one of our chemists discovered it for first time.  When first posted, the commentary sparked a lot of interest and we've decided to revisit it this November because it speaks to one of the fundamental principals of our Adesis catalog.  Thou shalt not list a compound that is not truly IN STOCK.  We hope you'll enjoy Derek's post and if you do not already read Derek's Blog, here's a great chance to discover an inspired voice for our industry.  


Seminars: Adesis SAB member, Amos B. Smith III (Rhodes-Thompson Professor of Chemistry at U Penn), presented a fascinating seminar to the Adesis team on October 14.  Entitled, "Evolution of Anion Relay Chemistry (ARC): Discovery and Applications", the seminar highlighted this effective multi-component synthesis tool, which was developed in the Smith Laboratory.  Used to decrease the number of steps for complex syntheses, ARC facilitates the building of molecular complexity in a single synthetic step.  Smith's seminar illustrated numerous examples of using ARC to prepare diverse molecules such as natural products and 'natural product-like' compounds.  For a recent reference, see: Angew. Chem. Int. Ed. 2011, 50,  8904-8907 and references cited therein.  


Round-tables: Andrew Cottone, VP of Chemistry and co-founder of Adesis participated in a hi-tech research roundtable event lead by Delaware Senator, Chris Coons.  Read all about how Delaware is supporting innovation and creating opportunities for cutting edge research in the First State.  Blog.  






3 Easy Ways to Search Our Online Catalog 



Informex 2012



Informex New Orleans - February 14-17, 2012 (#946)

End Of Year Catalog and Custom Synthesis Incentives   

Some companies find they have unused research funds available as they approach the end of the year.  In case you do have some "End-of-Year" spending money, give us a call to see what purchasing incentives can be found in placing large catalog or custom synthesis orders.

Catalog Inquiries: Jack Church - 302-323-6305
Custom Synthesis Inquiries: Ronald Yarger - 302-261-3383  

 catalog e-news


Compounds of the Month

Hot New Heterocycles 


Many of our substituted 1,7-azaindoles are popular with research chemists.  More recently we have introduced imidazo-pyridines, azaindazoles and deazapurines that allow one to explore the effects of increased heteroatoms in the ring core.  Alternatively, the effect of oxygen instead of nitrogen can be explored with our substituted furopyridines. 


To see all of our new heterocycles Click here 




About Adesis

Adesis, Inc. is a contract research organization (CRO) supporting the pharmaceutical and biopharmaceutical industry, biomaterials and catalysts industry. 


The life science industry has embraced the philosophy of outsourcing reference standards (competitor's drugs), targets, scaffolds, building blocks and advanced intermediates. Outsourcing allows medicinal chemists to focus on design and assembly of new targets for pharmacological evaluation and streamlines the early stage drug discovery process. Similarly, other chemistry-based research organizations (catalysts, biomaterials and fragrances) have accepted similar modus of operendi in order to maximize cost controls, while having timely project successes.


The core foundation of Adesis, Inc. is attributed to our experienced chemists with the expertise to conduct complex multi-step synthetic sequences (typical range of 2 - 20 steps).



15% Off Any 

1 Gram Order

November Promotion: 15% Off of  1 gram Catalog Order

Buy 1 gram of any catalog compound in November, mention this coupon at time of purchase, and save 15%...It's that easy.


Please call Jack Church to place your order: 302-323-6305 or email

Offer Expires: November 30th, 2011 
Only one offer per person.  

We hope you have enjoyed reading our Adesis newsletter.  We welcome your comments.


With Best Wishes,


Paul Beard


If you are interested in how your company can do business with Adesis or to learn more about our capabilities, please contact one of the members of our business development team.


Ronald G. Yarger, PhD

Director, Business Development 

Ph. 302-261-3383; Mobile 302-358-8837 



Paul Beard, MBA BS 

Business Development Associate 

Ph. 302-323-6314; Mobile 302-383-5918