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January 2009: Official e-Newsletter of the Medical Society

Keeping you InforMed about the latest health care news!

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In This Issue
New Gene Identified
Inheritance & Breast Cancer
Innovations in Women's Health Symposium
New Executive Director
Conquering Childhood Cancer
Degarelix Receives FDA Approval
Dr. Riveland photo


From the President





Brian R. Riveland, M.D.


Happy New Year to all.  It is my honor to be your Maricopa County Medical Society president for 2009.  I wish to express my thanks and appreciation for the leadership of Dr. Ed Donahue over this last year and look forward to his continued input on the Board. 

I grew up in Nebraska, completed residency at the University of Cincinnati and I have been in private practice in Internal Medicine since 1987 in Glendale.  I am fortunate to practice with 14 internists and several other providers at Thunderbird Internal Medicine who I consider my friends as well as partners and colleagues.   I have enjoyed participating in various committees, leadership positions and physician organizations throughout the last 21 years with a keen interest in information systems and clinical and service quality. 

At the time of this writing the country and the world are facing unprecedented economic times.  The country continues to be embroiled in conflicts overseas, countless people are experiencing foreclosures, layoffs, and hardships unimaginable a few short years ago.  There is talk of slipping into a full blown depression.   We all are seeing patients who in addition to their medical concerns are having now to deal with lack of income, making choices to not take their medicines or have recommended testing. They are simply trying to survive.  I am continually reminded that my concerns are petty and few compared with many of those I care for.

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Scientists Identify New Gene

A team of scientists has discovered a new syndrome associated with severe congenital neutropenia (SCN), a rare disorder in which children lack sufficient infection-fighting white cells, and identified the genetic cause of the syndrome: mutations in the gene Glucose-6-phosphatase, catalytic subunit 3 (G6PC3). The findings, which are published in the Jan. 1, 2009 issue of The New England Journal of Medicine, were made by an international team of scientists, composed of 14 researchers from the Medical School of Hannover in Germany and 12 from other research institutions, including the National Center for Biotechnology Information at the National Library of Medicine, National Institutes of Health.

"Our discovery will help facilitate genetic diagnosis in this newly defined group of severe congenital neutropenia patients," said Christoph Klein, M.D., Ph.D., Hannover Medical School, the principal investigator of the study. "Knowledge about the underlying genetic defect is an important first step in developing a targeted therapy."

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Inheritance Plays Important Role in
Breast Cancer
New research in mice and five independent collections of human breast tumors has enabled National Cancer Institute (NCI) scientists to confirm that genes for factors contributing to susceptibility for breast cancer metastasis can be inherited. The new findings support earlier results from the same laboratory and appear in the Jan. 1, 2009, issue of Cancer Research.

The study results also show that gene activities in tumor cells and immune cells that infiltrate, or invade, tumors can contribute to the development of expression profiles, called gene signatures that are predictive of cancer progression. The analysis of normal mouse tissue as well as tumors transplanted into mice suggests that predictive, or prognostic, gene signatures that point to a tumor's potential for spreading throughout the body can be the result of both inherited and non-inherited factors, with inherited factors being more consistently predictive. The research team that reported these findings is from the Center for Cancer Research at NCI, which is part of the National Institutes of Health.

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32nd Annual Innovations in
Women's Health Symposium
February 19-21, 2009
Buttes Marriott, Tempe, AZ
Co-sponsored by Phoenix Ob/Gyn Society
& ACOG AZ Section


- 15 Category I Credits             - Live Tele-Surgeries
- Relevant Topics                    - Audience Response System
- Gorgeous Location               - Dynamic Presenters
- Discount for MCMS Members

Click here to view brochure and registration form.
Mark your calendar and register today!

For more information, please call 602-864-1233, Ext. 5
AZ Osteopathic Board Names New Exec Director
The Arizona Board of Osteopathic Examiners in Medicine and Surgery has selected Elaine LeTarte to head the agency that licenses and regulates osteopathic physicians (DOs) in the state.  She succeeds Jack Confer who is now the Executive Director of the Kansas Board of Healing Arts.

The role of Executive Director is a familiar one for Ms. LeTarte.  She brings more than ten years' experience in professional licensing to the position, but this is also the second time she has been Executive Director of the DO Board.   Ms. LeTarte views the strength of the staff and the structure of the Board as positives that have remained unchanged.  But after almost four years, she recognizes some things are not the same.  During her first tenure as Executive Director, she worked with a Board nucleus that had been together for ten years.  Today's Board is for her, a "second generation" of sorts.  "They represent a different dynamic," she says.  "That's good because they bring new ideas and new perspectives."  Their input is important because of the increasing shift toward specialties among osteopaths.   
 
Ms. LeTarte sees the growing number of licensees helping to deliver quality healthcare to a rapidly increasing population in Arizona.  At the present time, about 1,600 of the slightly more than 2,000 licensed DOs practice in this state.  And now, there are two osteopathic medical schools training future practitioners: Midwestern University in Glendale and A.T. Still University in Mesa.  "The presence of two medical schools will make people more comfortable and familiar with the osteopathic profession," she says.
 
Looking to the future, Ms. LeTarte believes the Osteopathic Board will become more involved on a national level, particularly in areas that are crossing professions and state lines.
Conquering Childhood Cancer

EVENT:                  DONALD K. BUFFMIRE LECTURE
                                     Conquering Childhood Cancer:
                                     A Paradigm for Translational Research

SPEAKER:                William F. Crist, MD, VP for health affairs, U of A

DATE/TIME:     Wednesday 1/14/09, 4 p.m. reception
                                     5:30 p.m. lecture

LOCATION:             The U of A College of Medicine,
                                     Phoenix, in partnership with ASU
                                     Virginia G. Piper Auditorium
                                     550 E. Van Buren, Phoenix

COST:                         Lecture is free and open to the public.

RSVP/CONTACT:     Gail Skeens, (602) 827-2039

The University of Arizona College of Medicine-Phoenix in partnership with Arizona State University and the Flinn Foundation will host Dr. Crist, who will talk about his experience in a presentation titled, "Conquering Childhood Cancer: A Paradigm for Translational Research," on Wednesday, Jan. 14, 2009 at 5:30 p.m., in the Virginia G. Piper Auditorium, 550 E. Van Buren. The lecture is free and open to the public.  Parking in the College of Medicine lot, with entrance on 7th Street, also is free.

Dr. Crist is among the scientists credited with dramatically improving our understanding of childhood leukemias and their treatments. He spent much of his career from the 1970s through the 1990s in the field of pediatric hematology and oncology first at the University of Alabama, Birmingham, the University of Tennessee College of Medicine at Memphis, and St. Jude Children's Hospital in Memphis before becoming chairman of pediatric and adolescent medicine at Mayo Medical Center in Rochester, Minn. Dr. Crist had been serving as dean of the School of Medicine at the University of Missouri before being named UA VP for health affairs last summer.
FDA Approval
The U.S. Food and Drug Administration recently approved the injectable drug Degarelix, the first new drug in several years for prostate cancer.

Degarelix is intended to treat patients with advanced prostate cancer. It belongs to a class of agents called gonadotropin releasing hormone (GnRH) receptor inhibitors. These agents slow the growth and progression of prostate cancer by suppressing testosterone, which plays an important role in the continued growth of prostate cancer.

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