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A website sponsored by American Society of Clinical Oncology (ASCO) highlighting the history of cancer research and advances over 40 years.

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for Patients  


The American Institute for Cancer Research

Linking Diabetes to Cancer: Changes for Prevention

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Foods that Fight Cancer

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Obesity and Colorectal Cancer

A press release from the American College of Gastroenterology & the Campaign to End Obesity

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Providing easy, online access to government information on food and human nutrition for consumers

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Cancer Health Center

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Continuing Education

Schwartz Rounds 

Second Thursday of the month 12:00 PM  

Lunch is provided

Smilow Cancer Hospital at Yale-New Haven in the Park Street Auditorium (CME)  

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Yale Bioethics Center End of Life Issues Study Group   

77 Prospect Street, Rm A002

See website for full schedule


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October 19

Caring for the Elderly at End-of-Life: An Interdisciplinary Approach

Connecticut Coalition to Improve End-of-Life Care

Supported by the Connecticut Cancer Partnership 

Cromwell, CT 

CNE & CE for social workers



November 8 - 11

Buddhist Contemplative Care Symposium 2012: Palliative, Hospice, and Contemplative Care  

Garrison, NY

CE for nurses, social workers, & physicians

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May 24 - 25 

Art & Science of Palliative Nursing: 10th Anniversary offering


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Persistent and Breakthrough Cancer Pain: An Expert Video Roundtable

(CME, CNE)  

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May  2012       Volume 6 No 3


Peds, Adult, or AYA


Most healthcare delivery is organized around "pediatric medicine" (usually up to age 18) and "adult medicine." At the extremes, neonatology and gerontology have becomes specialties, with geriatric oncology also becoming a recognized subspecialty. A new age-grouping of cancer patients and survivors is being recognized: Adolescent and Young Adult, or AYA. There is a growing understanding that this group is not only developmentally and socially different from children and older adults, but also medically different.


There is no 'official' definition of AYA. The lower age range is usually around 15. The upper age range may be 29, 39, or even older. Psychosocially, 29 makes sense because some cognitive skills and emotion-driven behavioral patterns mature in the mid-twenties. Developmentally, there are both similarities and dramatic differences between older adolescents and people in their thirties. Medically, and specifically related to cancer, the more prevalent cancer types, incidence, and survival rates for AYA differs from both younger children and older adults. A 2006 NCI monograph* on cancer epidemiology in this group reported that, despite improvements in other age groupings, survival rates in 15-29 year olds have not budged in decades, and the incidence of cancer has been increasing over the past quarter-century. While not common, cancer in the 15-29 age range is three times more frequent in incidence than in the first fifteen years of life.


Recent articles (see select list below) highlight the complex environment that AYA's must negotiate, from diagnosis through survivorship. They also point out the dearth of research and lack of clinical programs and services devoted to this age group. Lack of awareness of the distinctiveness of this group and its unique needs is a major barrier that is slowly beginning to dissolve. In addition to the NCI monograph and the sample of articles below, the National Comprehensive Cancer Network (NCCN) has recently released new clinical practice guidelines for this group. The guidelines will be published in the May 2012 issue of the Journal of the National Comprehensive Cancer Network.


*Bleyer A, O'Leary M, Barr R, Ries LAG (eds): Cancer Epidemiology in Older Adolescents and Young Adults 15 to 29 Years of Age, Including SEER Incidence and Survival: 1975-2000. National Cancer Institute, NIH Pub. No. 06-5767. Bethesda, MD 2006.

  • Bellizzi KM, et al. Positive and negative psychosocial impact of being diagnosed with cancer as an adolescent or young adult. Cancer. 2012 Mar 13.
  • Keegan TH, et al. Unmet adolescent and young adultcancer survivors information and service needs: a population-based cancer registry study. J Cancer Surviv. 2012 Mar 29.
  • Kent EE, et al. "You're too young for this": Adolescent and Young Adults' Perspectives on Cancer Survivorship. J Psychosoc Oncol. 2012 Mar;30(2):260-79.
  • Soliman H, Agresta SV. Current issues in adolescent and young adult cancer survivorship. Cancer Control. 2008 Jan;15(1):55-62.
  • Zebrack B, Isaacson S. Psychosocial care of adolescent and young adult patients with cancer and survivors. J Clin Oncol. 2012 Apr 10;30(11):1221-6.
  • See also

In the News

National Healthcare Decisions Day exists to inspire, educate & empower the public & providers about the importance of advance care planning. National Healthcare Decisions Day is an initiative to encourage patients to express their wishes regarding healthcare and for providers and facilities to respect those wishes, whatever they may be.

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  • American Geriatric Society 2012 Beers Criteria is 
  • now available online. Guidelines for safe mediation use in older adults. See full article below in Other Articles of interest.

  • Journal Watch


  • The most recent issue of Current Cardiology Reviews [Vol 7 # 4, November 2011] is devoted to cancer treatment-related cardiotoxicity and features articles by several Yale-affiliated clinicians and researchers.  Unfortunately, Cushing Library does not subscribe, but individual articles are available through interlibrary loan.
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    The journal Cancer has published a supplement [15Apr 2012;118 (S8)] of 16 articles on rehabilitation and breast cancer.



    Alfano CM, et al. Cancer Survivorship and Cancer Rehabilitation: Revitalizing the Link. J Clin Oncol. 2012 Feb 21. 



    Mann, E. et al. Cognitive behavioural treatment for women who have menopausal symptoms after breast cancer treatment (MENOS 1): a randomised controlled trialLancet Oncol. 2012 Mar;13(3):309-18. 

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    Rausch SM, et al. Health behaviors among cancer survivors receiving screening mammography. Am J Clin Oncol. 2012 Feb;35(1):22-31. 

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    Palliative and Supportive Care

    Argyriou AA, et al. Chemotherapy-induced peripheral neurotoxicity (CIPN): An update. Crit Rev Oncol Hematol  



    Bennett MI, et al. Prevalence and aetiology of neuropathic pain in cancer patients: a systematic review. Pain. 2012 Feb;153(2):359-65.  

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    Carlson LE, et al. Screening for Distress and Unmet Needs in Patients With Cancer: Review and Recommendations. J Clin Oncol. 2012 Mar 12.  

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    Johnson RL, et al. Cancer-Related Fatigue. Evidence-based recommendations for management. Am J Nurs. 2012 Apr;112(4):57-60.  

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    McLaughlin SA. Lymphedema: Separating Fact from Fiction. Oncology. 2012;26(3):242-249.   


      • Commentary on McLaughlin article: Soran A, et al. Lymphedema Prevention and Early Detection: A Worthy Goal. Oncology. 2012;26(3):249, 254, 256,
      • Commentary on McLaughlin article: Hardin R, Jacobs LK. Lymphedema: Still a Problem Without an Answer. Oncology. 2012;26(3):256-257.
    Reeves DJ, et al. Successful desensitization to docetaxel after severe hypersensitivity reactions in two patients. Am J Health Syst Pharm. 2012 Mar 15;69(6):499-503.



    Other Articles of Interest

    The American Geriatrics Society 2012 Beers Criteria Update Expert Panel. American Geriatrics Society Updated Beers Criteria for Potentially Inappropriate Medication Use in Older Adults. J Am Geriatr Soc. 2012 Feb 29.  Read More >> 

    Emanuel R, et al. The Cinderella of Medical Disciplines. J Clin Oncol. 2012 Mar 5.  

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    Thun MJ, et al. The role of aspirin in cancer prevention. Nat Rev Clin Oncol. 2012 Apr 3. doi: 10.1038/nrclinonc.2011.199.   

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    Wegwarth O et al. Do physicians understand cancer screening statistics? A national survey of primary care physicians in the United States. Ann Intern Med 2012 Mar 6; 156:340.